M
Mette K. Andersen
Researcher at Copenhagen University Hospital
Publications - 165
Citations - 6963
Mette K. Andersen is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Population & Leukemia. The author has an hindex of 41, co-authored 148 publications receiving 6152 citations. Previous affiliations of Mette K. Andersen include University of Helsinki & Centre national de la recherche scientifique.
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Journal ArticleDOI
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk
Fergus J. Couch,Xianshu Wang,Lesley McGuffog,Andy C. H. Lee,Curtis Olswold,Karoline Kuchenbaecker,Penny Soucy,Zachary S. Fredericksen,Daniel Barrowdale,Joe Dennis,Mia M. Gaudet,Ed Dicks,Matthew L. Kosel,Sue Healey,Olga M. Sinilnikova,Adam M. Lee,Francois Bacot,Daniel Vincent,Frans B. L. Hogervorst,Susan Peock,Dominique Stoppa-Lyonnet,Anna Jakubowska,Paolo Radice,Rita K. Schmutzler,Susan M. Domchek,Marion Piedmonte,Christian F. Singer,Eitan Friedman,Mads Thomassen,Thomas Hansen,Susan L. Neuhausen,Csilla Szabo,Ignacio Blanco,Mark H. Greene,Beth Y. Karlan,Judy Garber,Catherine M. Phelan,Jeffrey N. Weitzel,Marco Montagna,Edith Olah,Irene L. Andrulis,Andrew K. Godwin,Drakoulis Yannoukakos,David E. Goldgar,Trinidad Caldés,Heli Nevanlinna,Ana Osorio,Mary Beth Terry,Mary B. Daly,Elizabeth J. van Rensburg,Ute Hamann,Susan J. Ramus,Amanda E. Toland,Maria A. Caligo,Olufunmilayo I. Olopade,Nadine Tung,Kathleen Claes,Mary S. Beattie,Melissa C. Southey,Evgeny N. Imyanitov,Marc Tischkowitz,Ramunas Janavicius,Esther M. John,Ava Kwong,Orland Diez,Judith Balmaña,Rosa B. Barkardottir,Banu Arun,Gad Rennert,Soo Hwang Teo,Patricia A. Ganz,Ian G. Campbell,Annemarie H. van der Hout,Carolien H.M. van Deurzen,Caroline Seynaeve,Encarna B. Gomez Garcia,Flora E. van Leeuwen,Hanne Meijers-Heijboer,Johannes J. P. Gille,Margreet G. E. M. Ausems,Marinus J. Blok,Marjolijn J. L. Ligtenberg,Matti A. Rookus,Peter Devilee,Senno Verhoef,Theo A. M. van Os,Juul T. Wijnen,Debra Frost,Steve Ellis,Elena Fineberg,Radka Platte,D. Gareth Evans,Louise Izatt,Rosalind A. Eeles,Julian Adlard,Diana Eccles,Jackie Cook,Carole Brewer,Fiona Douglas,Shirley Hodgson,Patrick J. Morrison,Lucy Side,Alan Donaldson,C. E. Houghton,Mark T. Rogers,Huw Dorkins,Jacqueline Eason,Helen Gregory,Emma McCann,Alex Murray,Alain Calender,Agnès Hardouin,Pascaline Berthet,Capucine Delnatte,Catherine Noguès,Christine Lasset,Claude Houdayer,Dominique Leroux,Etienne Rouleau,Fabienne Prieur,Francesca Damiola,Hagay Sobol,Isabelle Coupier,Laurence Venat-Bouvet,Laurent Castera,Marion Gauthier-Villars,Mélanie Léoné,Pascal Pujol,Sylvie Mazoyer,Yves-Jean Bignon,Elżbieta Złowocka-Perłowska,Jacek Gronwald,Jan Lubinski,Katarzyna Durda,Katarzyna Jaworska,Tomasz Huzarski,Amanda B. Spurdle,Alessandra Viel,Bernard Peissel,Bernardo Bonanni,Giulia Melloni,Laura Ottini,Laura Papi,Liliana Varesco,Maria Grazia Tibiletti,Paolo Peterlongo,Sara Volorio,Siranoush Manoukian,Valeria Pensotti,Norbert Arnold,Christoph Engel,Helmut Deissler,Dorothea Gadzicki,Andrea Gehrig,Karin Kast,Kerstin Rhiem,Alfons Meindl,Dieter Niederacher,Nina Ditsch,Hansjoerg Plendl,Sabine Preisler-Adams,Stefanie Engert,Christian Sutter,Raymonda Varon-Mateeva,Barbara Wappenschmidt,Bernhard H. F. Weber,Brita Arver,Marie Stenmark-Askmalm,Niklas Loman,Richard Rosenquist,Zakaria Einbeigi,Katherine L. Nathanson,Timothy R. Rebbeck,Stephanie V. Blank,David E. Cohn,Gustavo C. Rodriguez,Laurie Small,Michael Friedlander,Victoria L. Bae-Jump,Anneliese Fink-Retter,Christine Rappaport,Daphne Gschwantler-Kaulich,Georg Pfeiler,Muy-Kheng Tea,Noralane M. Lindor,Bella Kaufman,Shani Shimon Paluch,Yael Laitman,Anne-Bine Skytte,Anne-Marie Gerdes,Inge Søkilde Pedersen,Sanne Traasdahl Moeller,Torben A Kruse,Uffe Birk Jensen,Joseph Vijai,Kara Sarrel,Mark E. Robson,Noah D. Kauff,Anna Marie Mulligan,Gord Glendon,Hilmi Ozcelik,Bent Ejlertsen,Finn Cilius Nielsen,Lars Jønson,Mette K. Andersen,Yuan Chun Ding,Linda Steele,Lenka Foretova,Alex Teulé,Conxi Lázaro,Joan Brunet,Miquel Angel Pujana,Phuong L. Mai,Jennifer T. Loud,Christine Walsh,Jenny Lester,Sandra Orsulic,Steven A. Narod,Josef Herzog,Sharon Sand,Silvia Tognazzo,Simona Agata,Tibor Vaszko,JoEllen Weaver,Alexandra V. Stavropoulou,Saundra S. Buys,Atocha Romero,Miguel de la Hoya,Kristiina Aittomäki,Taru A. Muranen,Mercedes Durán,Wendy K. Chung,Adriana Lasa,Cecilia M. Dorfling,Alexander Miron,Javier Benitez,Leigha Senter,Dezheng Huo,Salina B. Chan,Anna P. Sokolenko,Jocelyne Chiquette,Laima Tihomirova,Tara M. Friebel,Bjarni A. Agnarsson,Karen H. Lu,Flavio Lejbkowicz,Paul A. James,Per Hall,Alison M. Dunning,Daniel C. Tessier,Julie M. Cunningham,Susan L. Slager,Chen Wang,Steven N. Hart,Kristen N. Stevens,Jacques Simard,Tomi Pastinen,Vernon S. Pankratz,Kenneth Offit,Douglas F. Easton,Georgia Chenevix-Trench,Antonis C. Antoniou +261 more
TL;DR: It is estimated that the breast cancer lifetime risks for the5% of BRCA1 carriers at lowest risk are 28%–50% compared to 81%–100% for the 5% at highest risk, and the ovarian cancer lifetime risk is 63% or higher, based on the known cancer risk-modifying loci.
Journal ArticleDOI
Mutations With Loss of Heterozygosity of p53 Are Common in Therapy-Related Myelodysplasia and Acute Myeloid Leukemia After Exposure to Alkylating Agents and Significantly Associated With Deletion or Loss of 5q, a Complex Karyotype, and a Poor Prognosis
TL;DR: Mutations with loss of function of p53 are significantly associated with deletion or loss of 5q in t-MDS and t-AML after previous treatment with alkylating agents and are associated with genetic instability.
Journal ArticleDOI
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in malignant disease
TL;DR: The clinical description of the syndrome has changed little since the original observation, and the cardinal findings of SIADH are as follows: hyponatremia with corresponding hypo‐osmolality of the serum and extracellular fluid, continued renal excretion of sodium, absence of clinical evidence of fluid volume depletion.
Journal ArticleDOI
TP53 mutations identify younger mantle cell lymphoma patients who do not benefit from intensive chemoimmunotherapy
Christian Winther Eskelund,Christina Dahl,Jakob Werner Hansen,Maj Westman,Arne Kolstad,Lone Bredo Pedersen,Carmen P. Montano-Almendras,Simon Husby,Catja Freiburghaus,Sara Ek,Anja Pedersen,Carsten Utoft Niemann,Riikka Räty,Peter de Nully Brown,Christian H. Geisler,Mette K. Andersen,Per Guldberg,Mats Jerkeman,Kirsten Grønbæk +18 more
TL;DR: TP53 mutations identify a phenotypically distinct and highly aggressive form of MCL with poor or no response to regimens including cytarabine, rituximab, and autologous stem-cell transplant (ASCT).
Journal ArticleDOI
Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia.
TL;DR: Therapy-related acute myeloid leukemia (t-AML) in most cases develops after chemotherapy of other malignancies and shows characteristic chromosome aberrations.