Showing papers in "Frontiers in Neuroendocrinology in 2006"

TL;DR: The distribution of BDNF and trkB expressing cells in the forebrain, and the roles of estrogen and the BDNF-trkB neurotrophin system in Parkinson's disease, Alzheimer's disease and multiple sclerosis are described.

TL;DR: A tri-molecular cascade, estrogen-BDNF-NPY, may be important in understanding the hormonal regulation of hippocampal function and may provide greater insight into neurological disorders and psychiatric illness, including Alzheimer's disease, depression and epilepsy.

TL;DR: Using a novel immature-rodent model, the deleterious consequences of chronic early-life 'psychological' stress on hippocampus-dependent cognitive tasks are described and the cellular mechanisms involved are reviewed.

TL;DR: By targeting, for example, vocal motor circuits without inappropriate steroid exposure to other steroid-dependent circuits, such as those involved in either copulatory or spawning behaviors, the neuroendocrine system can achieve temporal and spatial specificity in its modulation of neural circuits that lead to the performance of any one behavior.

TL;DR: The data on functions of the estrogen receptor beta (ERbeta) in both behavior and neuroendocrinology are reviewed to suggest a unique function for ERbeta in sexual differentiation; its activation in male neonates may promote defeminization of sexual behavior.

TL;DR: The state of the art concerning Y(1)R function and gene expression is reviewed, including the personal contribution to many of the subjects mentioned above.

TL;DR: Comparing and contrast studies examining aggression in birds, mammals, and humans is compared and mechanisms that could explain species differences in how estrogen modulates aggression are considered.

TL;DR: This work reviews the processes involved in forming a functional nuclear group and some of the factors known to be involved particularly focusing on the positioning of identified neurons within the VMH.

TL;DR: The role of reproductive steroids in affect regulation and in premenstrual dysphoric disorder (PMD), parses PMD into component processes that suggest potential mediating neurocircuitry, and highlights the importance of and potential contributors to the differential sensitivity that permits reproductive steroids to destabilize mood in some but not all women.

TL;DR: Observations reveal diverse inhibitory actions of cortisol on gonadotropin secretion and that this glucocorticoid is not only sufficient, but necessary for suppression of reproductive neuroendocrine activity in response to certain types of stress.

TL;DR: ERs appear to be part of the signaling mechanism of IGF-I, and IGF-i receptor part ofThe mechanism of estradiol signaling in the nervous system.

TL;DR: The neuroendocrine mechanisms for stress hyporesponsiveness are likely to include reduced synthesis and secretion of corticotropin releasing hormone (CRH) and arginine vasopressin (AVP) from the hypothalamus as a result of enhanced glucocorticoid negative feedback and/or reduced noradrenergic stimulatory input from the brain stem.

TL;DR: A review of the role of progesterone and its receptor in male-typical reproductive behaviors in adulthood and the role in neural development, in both sexual differentiation of the brain as well as in the development of "non-reproductive" functions is discussed.

TL;DR: It appears that estrogen is assuming control over or at least influences a multitude of developmental and protective cellular mechanisms rather than taking over the part of a singular protagonist.

TL;DR: DR rats show elevated basal and orexin A-induced SPA associated with increased OX1R and OX2R gene expression, suggesting that differences in orexIn A signaling through OX 1R andOX 2R may mediate DIO and DR phenotypes.

TL;DR: MAPK is involved in the facilitation of lordosis and proceptive behaviors, perhaps by phosphorylation of hypothalamic PRs, and interference with MAPK signaling inhibits behavioral responses to cGMP and a delta-opioid agonist.

TL;DR: Findings from new genetic models indicate a critical role for GR signaling in the CNS in normal regulation of the HPA axis and behavioral/emotional stability.

TL;DR: These studies provide a neurobiological foundation for the profound neuroplasticity of stress-related genes evoked by early-life experience on the expression of genes regulating hormonal and behavioral responses to stress.

TL;DR: Exposure to methanol-induced oxidative stress disturbs the HPA-axis function altering the level of corticosterone, which lead to varied non-specific and specific immune response in experimental rats.

TL;DR: Ultrasound-guided, transvaginal, ovarian, interstitial laser treatment appears effective in improving hormonal profiles and inducing ovulation and successful pregnancy in women with clomifene-resistant PCOS.