Showing papers in "International Journal of Cardiology in 2012"

TL;DR: The data indicate that the cardiovascular effects of levosimendan are exerted via more than an isolated drug-receptor interaction, and involve favorable energetic and neurohormonal changes that are unique in comparison to other types of inodilators.

TL;DR: While prostacyclin and its analog, iloprost, prevent CIN by inducing medullary vasodilatation, atrial natriuretic peptide (ANP) may do so by inhibiting renin secretion.

TL;DR: Active carrier-mediated intestinal transport is reduced in decompensated CHF indicating epithelial dysfunction possibly as a consequence of intestinal ischemia and higher LPS concentrations in edematous CHF relate to inflammation.

TL;DR: Among patients with T2DM and cardiovascular co-morbidity, overweight and obese patients had a lower mortality compared to patients with normal weight and there may be an "obesity paradox" in patients with type 2 diabetes and cardiovascular risk.

TL;DR: EAT volume positively relates to coronary atherosclerotic burden, as assessed by CAC; this correlation was shown to be independent of AVF.

TL;DR: The findings suggest that disease activity plays an important role for the cardiovascular manifestations of TA, and patients with higher activity have more cardiovascular morbidity compared to the TA patients with low disease activity.

TL;DR: MD1-patients have a high level of cardiac morbidity and mortality, strongly emphasizing the need of pre-symptomatic screening for arrhythmia and heart failure, as effective and well-documented preventive means are available.

TL;DR: Left and right ventricular function both by CMR and speckle-tracking is interrelated in adults with repaired ToF, suggesting subclinical LV myocardial damage.

TL;DR: Although many studies have shown that weight loss in elderly patients is associated with a poor prognosis, recent data demonstrate that intentional weight reduction in obese elderly people ameliorates the cardiovascular risk profile, reduces chronic inflammation and is correlated with an improved quality of life.

TL;DR: In adult patients with congenital heart disease, mortality shows substantial regional and subtle seasonal variation and is almost equally distributed throughout the seasons.

TL;DR: This prospective, randomized trial suggests that PC did not have the expected cardioprotective effect and on the contrary it might harm STEMI patients treated by PPCI plus abciximab.

TL;DR: The presence of gHTN, EF ≥ 35% at diagnosis, breastfeeding, and postpartum diagnosis were all significantly associated with recovery of systolic function, suggesting internet recruitment may be a valuable tool for studying PPCM.

TL;DR: Addition of sildenafil in adult patients with CHD-related PAH and Eisenmenger syndrome after oral bosentan therapy failure is safe and well tolerated at 6-month follow-up, resulting in a significant improvement in clinical status, effort SpO(2), exercise tolerance and haemodynamics.

TL;DR: Patients with successful CTO recanalization had a trend towards better cardiac survival and significant lower risk of MACE and improvement of AQL compared to patients with failed procedures.

TL;DR: It is suggested that short-term L-citrulline supplementation may functionally improve arterial stiffness, independent of blood pressure, in humans.

TL;DR: In patients referred for TAVI, CMR measurements of aortic root dimensions show a good correlation with DSCT measurements and thus CMR may be an alternative 3D-imaging modality.

TL;DR: In symptomatic patients, the severity of symptoms, the magnitude of CK elevation and the risk/benefit ratio of statin continuation should be considered before statin treatment is discontinued, and the use of non-statin lipid lowering drugs requires evidence based recommendations.

TL;DR: This review article summarizes recent work on the cardiovascular actions of Adiponectin and indicates that ApN has direct myocardio-protective effects.

TL;DR: Ramipril is a well tolerated therapy, improves biventricular function in Patients with rTOF and may have a particular role in patients with restrictive RV physiology.

TL;DR: Exercise training for patients with HFPEF confers benefit in terms of enhancements in exercise capacity and health-related quality of life and appears to be safe.

TL;DR: This study suggests that HSYA can provide protection to H9c2 cardiomyocytes against A/R-induced apoptosis, and this protective effect largely depends on the upregulation of HO-1 expression through the PI3K/Akt/Nrf2 signaling pathway.

TL;DR: Telemedicine management may not be appropriate for all HF patients and future research needs to investigate which HF population may benefit from this intervention.

TL;DR: A high EAT volume was associated with the presence of vulnerable plaque components, independent of obesity measurements (BMI and VAT) and CAC scores.

TL;DR: It is demonstrated that TZDs had obvious protective effects on the development of AF in diabetic patients, and drugs acting as ligands to the PPAR-γ may be potential up-stream therapies for AF prevention.

TL;DR: Takotsubo cardiomyopathy goes along with a singular cardiac biomarker profile, which might be useful to identify patients with TC among patients presenting with acute coronary syndromes (ACS).

TL;DR: There is a higher frequency of persistent LBBB with the CoreValve system than with the Edwards SAPIEN prosthesis, and Implantation depth is a critical factor for the development of new L BBB.

TL;DR: Comorbidities and coexisting cardiac diseases are very common in AS and may strongly influence the decision-making process in patients with symptomatic aortic stenosis.

TL;DR: The purpose of the present review is to bring to the attention of medical and research communities those biomarkers for which a relevant amount of evidence has been accumulated regarding their potential application in all clinical steps of the cardiovascular continuum.

TL;DR: The 60 eligible RCTs indicate that DSP is apparently more effective than ISDN in treating angina pectoris, however, further R CTs of larger scale, multi-centre/country, longer follow-up periods, and higher quality are still required to verify the efficacy of DSP over all anti-anginal therapies.

TL;DR: This study demonstrated that leg BP was associated with AoRD in individuals with or without cardiovascular risk factors, and showed that changes in body posture played a role in this relationship, suggesting that legBP evaluation might be an alternative approach in order to predict AoRD.