Showing papers in "Natural Product Research in 2004"

TL;DR: In this paper, a new pentacyclic triterpenoid guajanoic acid was isolated from the leaves of Psidium guajava and characterized as 3beta-p-E-coumaroyloxy-2alpha-methoxyurs-12-en-28-oic acid.

TL;DR: A brief review of natural colourant sources, their classification, chemical constituents responsible for producing different colours, its activities and effect of different mordants on the hue is discussed.

TL;DR: The absolute from Zataria multiflora was explored for enzyme inhibition, insect repellent, and insecticidal activities and showed that thymol is the major constituent while carvacrol is themajor constituent in the absolute of dried plant.

TL;DR: The essential oil was found to be active against the bacteria Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Shigella sonnei, and Staphylococcus aureus and the yeast Candida albicans.

TL;DR: Quantitative determination of furanochromones in A. visnaga (L.) ripe fruits from Hatay region (Turkey) was carried out by ultraviolet spectrophotometry and gas chromatography, and photochemical properties and chemical composition of essential oil were determined.

TL;DR: A survey of the literature dealing with artemisinin related antimalarial issues that have appeared from 1980s to the beginning of 2003 is reported.

TL;DR: While screening for inhibitors of phosphatases among natural products, it was repeatedly found that some polyprenyl-hydroquinones and polymethine-furans (furanoterpenoids) (furospongins, furospinosulins) were potent CDC25 phosphatase inhibitors.

TL;DR: A new 7-geranyloxycoumarin has been isolated from the leaves of methanolic extract of Aegle marmelos belonging to the family Rutaceae and several known compounds have also been obtained for the first time from the same source.

TL;DR: Analysis of the dichloromethane extract of the aerial parts of Croton cuneatus led to the isolation of the new glutarimide alkaloids: juloc rotol, isojulocrotol, and jULocrotone along with the known compounds julOCrotonine, lichexanthone, and selin-11-en-4α-ol.

TL;DR: Five oxidative and reductive metabolites of androsta-1,4-diene-3,17-dione yielded microbially transformed products that were assayed against the clinically important enzymes, tyrosinase and prolyl endopeptidase.

TL;DR: The relatively high hypericin content of the H. triquetrifolium in this study encourages the introduction, cultivation, and biological evaluation of hypericum specie in Jordan.

TL;DR: Chemical investigation of n-butanol extract from the methanol extract of leaves of Grewia damine furnished lupeol, sitosterol β-D-glucoside, flavone C-glycosides vitexin, isoviteXin and 3-O-α-l-rhamnopyranosyl(1 → 2)-β-D

TL;DR: Bioassay-directed fractionation of the ethyl acetate extracts of the stem bark of Aegle marmelos Correa (Rutaceae) afforded a new compound, named skimmiarepin C, along with skimmuarepin A, which is a senecioate ester analogue of the latter.

TL;DR: Nine flavonoids have been isolated from the leaves and flowers of C. microphylla C. Koch.

TL;DR: A new tyrosol derivative, the oleic ester of tyrosols, was isolated from fruits of Olea europaea, Cassanese cultivar, and Salidroside, the known glucosyl derivative of thyrosol, wasisolated.

TL;DR: Some of the prenylindoles had antifungal and antimalarial activities and structural determination by spectroscopic analysis was obtained.

TL;DR: A new abietane diterpene, the 19-O-β-d-glucopyranoside of 16-hydroxylambertic acid was isolated from the leaves of Quillaja brasiliensis together with a known prosapogenin, quercetin, and rutin.

TL;DR: Two stilbene derivatives showed strong antifungal activity against Cladosporium cladosporioides and high radical scavenging activity towards the DPPH radical in TLC bio-autography method.

TL;DR: Further examination revealed the new natural product but known synthetic compound, esmodil, which was confirmed by spectroscopic analysis and total synthesis.

TL;DR: The air-dried flowers of Ixora coccinea L. afforded two new cycloartenol esters (1a and 1b), lupeol fatty ester, lupol, ursolic acid, oleanolic acid and sitosterol, which were elucidated by extensive NMR spectroscopy and MS.

TL;DR: The most profound inhibitory effect of podophyllotoxin was observed when it was applied in the beginning of cell growth and was able to inhibit the growth of the cancer cells by 50%.

TL;DR: Sixteen serratane-type triterpenoids including three new compounds, 14β,15β- epoxyserratan-3β,21β,29-triol, and serrat-14-en-3α, 21β,24, 29-tetraol, were isolated from the whole plant of Huperzia serrata (Thunb) Trev.

TL;DR: The studies of structure-FPTase inhibitory activity indicated that the number, position and substitution of hydroxyl groups of the A and B rings of flavonoid, and unsaturation of the C2–C3 bond are important factors affecting inhibition on FPTase by flavonoids.

TL;DR: The isolation and identification of mucigerin as well as bioassay data are reported, finding the crude extracts were also found to be moderately toxic against the larvae of Aedes aegypti.

TL;DR: A new sesquiterpene, and a halogenated C15 acetogenin, a stereoisomer of neoisoprelaurefucin were isolated from Laurencia obtusa, and four known compounds laurencienyne, rogiolenyne B, obtusenol, and (3E)-dactomelyne were also isolated from this alga.

TL;DR: A new tetracyclic triterpene 9,19-cyclolanost-22(22′), 24-diene-3β-ol, named as nerifoliene along with euphol were isolated from the fresh latex of Euphorbia nerifolia and their structures were elucidated on the basis of spectral data.

TL;DR: Two isocoumarins have been isolated from the ethyl acetate extract of the root of Pituranthos scoparius: 3-n-propyl-5-methoxy-6-hydroxy-isocou marin and 3- n-propYL-5,7-dimethoxy -6-Hydroxy- isOCoumarin.

TL;DR: Bioassay-guided fractionation of two Philippine sponges of the genus Petrosia has resulted in the isolation of the novel natural product cribrostatin 7 and the known compounds renierone and O-demethylrenierone.

TL;DR: Flow-cytometric analysis revealed that chondropsin A 1 and 73-deoxychondroPSin A 2 blocked the entry of HL 60 and KB cells into G2/M phase, leading to cell death by apoptosis.

TL;DR: Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp.