Showing papers in "Placenta in 1990"

TL;DR: These findings seem to be related to the untimely initiation of blood flow in the intervillous space which in turn is associated with arrest of pregnancy and eventual expulsion.

TL;DR: Using a panel of antibodies (monoclonal as well as polyclonal) to nerves, nerve tissue was not identified within the umbilical cord.

TL;DR: The evidence that a high titer of IL-6 is produced spontaneously by syncytiotrophoblasts indicates that IL- 6 may play immunological roles in fetomaternal interactions by means ofIL-6-driven multiple immunoregulatory activities.

TL;DR: It is concluded that birthweights are reduced at high altitude despite the attempts to increase the total placental diffusive conductance for oxygen.

TL;DR: The hypothesis that one function of the yolk sac in the rat is the synthesis and secretion of a select group of plasma proteins to maintain homeostasis in the fetal compartment in the period before the fetal liver has matured sufficiently to carry out this function is supported.

TL;DR: The synthesis of the r PLP-A and rPLP-B mRNAs in cells which have access only to the maternal circulation suggest that they have a role in the mother.

TL;DR: Results of several lines of inquiry indicate that, as with macrophages in other tissues, these cells are multi-functional, and further experimentation is likely to be technically demanding because of indications that intricate hormone-prostaglandin-cytokine networks regulate uterine macrophage activities.

TL;DR: The presence of fibronectin in infiltrating extravillous trophoblast, endovascular trophOBlast and in the distal columns may enhance trophoplast adhesion to maternal tissues and facilitate trophablast migration.

TL;DR: An in vitro suspension co-culture system to examine the interaction of 1st, 2nd and 3rd trimester purified cytotrophoblasts with human endometrium should prove useful for examining those factors which induce endometrial permissiveness, promote paracrine effects on the endometria, and facilitate human trophoblast invasion.

TL;DR: Gold acetyl LDL was internalized by the syncytiotrophoblast following the classical receptor mediated endocytosis process and a non-specific internalization process, suggesting the existence in the placenta of a 'scavenger pathway' concomittant of the classical LDL internalization.

TL;DR: The present findings suggest that cigarette smoke induced ERDE activity is a distinct one compared with the other xenobiotic-metabolizing P450s, and suggests that it is most closely related to the extent of maternal cigarette smoking.

TL;DR: The failure of antiserum to affect incorporation of [3H]leucine into the embryo probably indicates that leucine can enter the embryo without the mediation of yolk-sac pinocytosis, and the primacy of protein, as a source of amino acids for the organogenesis-stage embryo.

TL;DR: A preliminary investigation of the permeability properties of the preparation showed that the trophoblast cell layer was rate-limiting to transtrophoblast transfer, but that possible effects of the supporting membrane should be considered.

TL;DR: The continuous increase in the expression of PLAP throughout pregnancy suggests that PLAP may play a role in feto-maternal metabolism and placental differentiation.

TL;DR: Evidence is provided that vesicles derived mainly from the maternal facing plasma membrane of syncytiotrophoblast layer II of the rat placenta possess a Na+/H+ exchanger.

TL;DR: The quantitative studies uphold the hypothesis that at implantation in the goat, placental trin nucleate cells and their subsequent multinucleate syncytial plaque derivatives are fetomaternal hybrid tissue formed by fusion of a binucleate cell(s) with a single uterine epithelial cell.

TL;DR: In a quantitative analysis ofGMG cells in the maternal blood spaces of placentae no significant differences in the numbers of GMG cells present in these spaces or involved in an interaction with layer 1 labyrinthine trophoblast were detected between inbred and outbred pregnancies, suggesting that histocompatibility antigens are not significant factors in determining the frequency of interactions.

TL;DR: Human trophoblast cells with immunocytochemical characteristics of the extravillous population have been isolated from 1st trimester placentae and the possibility that aberrant production of IFN-gamma may upset the fetal-maternal equilibrium in vivo is discussed.

TL;DR: 59Fe release from trophoblast cells exceeded the release of lactate dehydrogenase and also exceeded therelease of 59Fe from 3T3 fibroblasts, suggesting a cell-specific process.

TL;DR: This case presents histological proof that choriocarcinoma may arise from an otherwise normal placenta, and Interpretation of this lesion was influenced by the presence of normal villi.

TL;DR: The availability of highly purified extravillous cytotrophoblast, for the first time, permits precise investigation of trophoblast function.

TL;DR: It was found that endothelium of fetal stem vessels in villitis areas was usually MHC class II (HLA-DR, DP and DQ) reactive, which can promote intravascular coagulation, ischemic necrosis, vasculitis and other histological changes characteristic of villitis.

TL;DR: There is now sufficient data available on the biological functions of this cytokine in other cellular systems to provide a conceptual framework upon which the influence of IFN on the human placenta may be based.

TL;DR: The EGF receptors on the syncytiotrophoblast were thought to be involved in the production and secretion of human chorionic gonadotropin and placental lactogen, probably under the control of maternal EGF.

TL;DR: Results show that placental glycogen is amenable to mobilization by hormonal stimuli effecting phosphorylase activation, and this effect was concentration dependent and of similar magnitude in non-diabetic and diabetic rat placentas.

TL;DR: The placentae in congenital syphilis were significantly heavier than expected for infant weight, and the routine use of placental weight-birth weight graphs is advocated, especially in infants who are underweight for gestational age and in areas where syphilis is prevalent.

TL;DR: The mammalian blastocyst provides a unique model for the study of the development of vectorial transport systems in epithelia and, in the future, of patterns of genes that regulate this development.

TL;DR: Eleven placentae and one fibroblast cell culture from pregnancies complicated by various inherited metabolic disorders, together with five chorionic villus biopsies from pregnancies at risk, were examined for ultrastructural evidence of accumulation of metabolites.

TL;DR: Results indicate that changes in Ca2+ modify hCG and hPL release from term placental explants in a manner concordant with the 'stimulus-secretion coupling' concept.

TL;DR: The carbonic anhydrase isoenzymes, low activity CAI and high activity CAII, were localized in normal term human placenta by immunocytochemical techniques and were present in the syncytial trophoblasts.