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Showing papers in "Theriogenology in 2018"


Journal ArticleDOI
TL;DR: This review will focus on the mechanisms of heat stress-induced sperm defects and provide more detailed insights into sperm-borne epigenetic regulations.

78 citations


Journal ArticleDOI
TL;DR: The use of fertility programs that include the concepts described in this review have resulted in more P/AI than inseminating cows after an induced estrus at first insemination, and extending these concepts to strategies for resynchronization of ovulation and the implementation of an aggressive reproductive management program results in reproductive performance that is unprecedented for high-producing Holstein dairy cows.

70 citations


Journal ArticleDOI
TL;DR: Investigation of the effect of heat stress on granulosa cells function and the associated defense mechanism found that reactive oxygen species level was higher in cells under 41 °C at 24 h compared to control, and NRF2 mediated oxidative stress and endoplasmic reticulum stress response by bovine granULosa cells were higher.

70 citations


Journal ArticleDOI
TL;DR: Several facets of sublethal freezing damage are explored, touching on cryocapacitation, the generation of reactive oxygen species and alterations to sperm proteins, lipids and sugars, and the cryoprotective potential of whole seminal plasma and individual proteins.

55 citations


Journal ArticleDOI
TL;DR: It is demonstrated that certain SP antioxidants are positively involved in boar sperm cryotolerance, minimizing the oxidative stress imposed by cryogenic handling.

53 citations


Journal ArticleDOI
TL;DR: It is found that 10-7 M melatonin increased testosterone production in co-cultured Leydig and Sertoli cells isolated from sheep, and this work suggests that melatonin may function through modulating melatonin receptor 1-regulated insulin-like growth factor-1 expression, as well as melatonin receptors 1-induced suppression of estrogen synthesis to increase androgen production in Co-culturing Leydigs and SERToli cells.

45 citations


Journal ArticleDOI
TL;DR: Early gestation circulating PAG concentration may have application in diagnosing pregnancy at day 24 of gestation and more work is needed to determine the potential of early gestation PAGs in predicting embryo loss in dairy cattle undergoing embryo transfer.

45 citations


Journal ArticleDOI
TL;DR: It is shown that de novo synthesis of sphingolipids is necessary in implantation and plays a key role in decidualization of mouse.

41 citations


Journal ArticleDOI
TL;DR: This work confirms the importance of some bacteria identified by culture-based studies in the pathogenesis of metritis such as Fusobacterium necrophorum and Prevotella melaninogenica; however, it challenges the important of others such as Escherichia coli and Trueperella pyogenes at the time of meetritis diagnosis.

39 citations


Journal ArticleDOI
TL;DR: The results confirm the hypothesis, indicating that prolonged parturition and impaired placenta expulsion increased the risk of postpartum metritis and delay uterine involution.

39 citations


Journal ArticleDOI
TL;DR: Evaluating the in vitro effect of some NETs components on mare endometrial fibrogenesis and determining its relationship with histopathology or estrous cycle proposes that NETs involvement in chronic endometritis in mares may act as putative endometrian fibrogenic mediators.

Journal ArticleDOI
TL;DR: The results suggest that the combination of resveratrol and melatonin supported a synergistic increase in oocyte nuclear maturation and total cell numbers of PA blastocysts and improved the development of SCNT embryos.

Journal ArticleDOI
TL;DR: The present study indicated that the early luteal phase uterus secretes exosomes, which might play important roles in the development of SCNT embryos.

Journal ArticleDOI
TL;DR: Some potential molecules in spermatozoa of bulls, which may act as a panel of biomarkers for fertility, are identified through proteomics approach.

Journal ArticleDOI
TL;DR: It is concluded that spermatozoa from bulls aged 10 months have a different epigenetic profile, which could compromise their value.

Journal ArticleDOI
Leying Zhang1, Jie Xue1, Qingkai Wang1, Wan Lv1, Hao Mi1, Yong Liu1, Ling Yang1 
TL;DR: It is reported for the first time that early pregnancy exerts its effects on the thymus through IFNT and P4 in sheep through the expression of ISG15, P4 receptor (PGR) and PIBF mRNA and the expression.

Journal ArticleDOI
TL;DR: The findings demonstrate that the combination of R and EGCG could positively affect frozen-thawed boar sperm fertility in vitro; the effect is evident also in R groups, thus demonstrating that this antioxidant is predominant, and no synergic effect is present.

Journal ArticleDOI
TL;DR: It is suggested that Se plays an important role in the proliferation of and steroidogenesis in LGC by activating the PI3K/Akt and AMPK pathways, thereby increasing the expression of its downstream cell-cycle- and steroid-synthesis-related genes, as well as regulating cellular oxidative stress.

Journal ArticleDOI
TL;DR: The beneficial effect of betaine is revealed on HS-induced complications of spermatogenesis, as well as its potency to improve epididymal spermatozoa in intact mice.

Journal ArticleDOI
TL;DR: Equine-derived endometrial MSC share biological attributes with adipose MSC of this species, but displayed a different surface marker phenotype and an impaired migration ability.

Journal ArticleDOI
TL;DR: The ANOVA test showed that the addition of glutathione significant affected the sperms motility, fertility and hatching rate of seurukan fish Osteochilus vittatus eggs (P < 0.05), and the conclusion was drawn that the optimum concentration of glutATHione is 40 mg L-1 of diluent.

Journal ArticleDOI
TL;DR: The sperm fatty acid composition of Shetland pony stallions undergoes seasonal changes, and PUFA content increases from the non-breeding to the breeding season, which might in part explain seasonal differences in the resistance of equine spermatozoa to cryopreservation and cooled-storage.

Journal ArticleDOI
TL;DR: Results from the angiogenesis bioassay suggest that kisspeptin may have a role in the physiological development of new ovarian vessels and additional studies are needed to confirm the functional significance of the kissedpeptin/KISS1R system within the swine ovary.

Journal ArticleDOI
TL;DR: The results suggest that protamine deficiency in bovine spermatozoa may not have a strong biological impact to explain the difference of in vitro fertility between the bulls used in this study.

Journal ArticleDOI
TL;DR: It is demonstrated that, additional feeding of organic Zn and Cu to growing male goats advanced onset of puberty and improved quantitative and qualitative semen characteristics are demonstrated.

Journal ArticleDOI
TL;DR: The results showed that supplementation of the rooster sperm extender with 1% soybean lecithin and 20% egg yolk plasma resulted in higher quality of frozen-thawed sperm.

Journal ArticleDOI
TL;DR: Chemical induced reduction of nucleic acid m6A methylation during pig oocyte meiosis could impair meiotic maturation and subsequent development potency, possibly through down-regulating pluripotency marker Lin28 mRNA abundance and disturbing MPF-regulated chromosome/spindle organization.

Journal ArticleDOI
TL;DR: It is demonstrated that vitrified/warmed oocytes need an extra time to restore damage due to cryopreservation procedures and to increase their developmental potential.

Journal ArticleDOI
TL;DR: The study reveals that the Interferon tau stimulated gene expression in neutrophils can act as peripheral biomarkers for detecting the embryonic mortality in dairy cows.

Journal ArticleDOI
TL;DR: These specific recombinant gonadotropins have demonstrated their capacity to induce spermatogenesis and spermiation in vivo in a teleost fish, the European eel.