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1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry
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This article is published in Chemical Reviews.The article was published on 2014-04-09. It has received 366 citations till now.read more
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Coumarin heterocyclic derivatives: chemical synthesis and biological activity
Fernanda G. Medina,Joaquín G. Marrero,Mariana Macías-Alonso,Magdalena C. Gonzalez,Iván Córdova-Guerrero,Ariana G. Teissier Garcia,Soraya Osegueda-Robles +6 more
TL;DR: This review highlights the broad range of science that has arisen from the synthesis of coumarin-linked and fused heterocycle derivatives and their synthesis and biological activity.
Journal ArticleDOI
A review of surfactants as corrosion inhibitors and associated modeling
TL;DR: A review of surfactants as corrosion inhibitors is designed to provide systemic evaluation of various physical and chemical properties, surfactant behaviors in corrosive environments, and their influence in corrosion inhibition.
Patent
Electrolyte for lithium secondary battery and lithium secondary battery comprising same
Jin-Sung Kim,Meen-Seon Paik,Jung-Joon Park,Young-Gyu Kim,Jongseob Kim,Hak-Soo Kim,Sang-jun Lee,Jae-Hou Nah,Sang-Moon Hwang,Chan-Jung Kim +9 more
TL;DR: In this article, an electrolyte for a high-voltage lithium secondary battery and a highvoltage Li-ion battery containing the same electrolyte is provided, which may not be oxidized and decomposed at the time of being kept at high voltage and high temperature to prevent swelling of a battery through suppression of gas generation.
Journal ArticleDOI
2-Amino-1,3,4-thiadiazole as a potential scaffold for promising antimicrobial agents.
TL;DR: The aim of this review was to highlight the main antimicrobial properties exhibited by derivatives possessing 2-amino-1,3,4-thiadiazole moiety, which can be considered as lead compounds for drug synthesis, and several of them have demonstrated higher antimicrobial activity in comparison to standard drugs.
Journal ArticleDOI
Coordination chemistry of thiazoles, isothiazoles and thiadiazoles
TL;DR: In this article, a review of the existing information in this field and some perspectives in the synthesis and applications of 1, 3-thiazole, isothiazole and thiadiazole metal complexes is presented.
References
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Free radicals and antioxidants in normal physiological functions and human disease
TL;DR: Attention is focussed on the ROS/RNS-linked pathogenesis of cancer, cardiovascular disease, atherosclerosis, hypertension, ischemia/reperfusion injury, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and ageing.
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Bioisosterism: A Rational Approach in Drug Design.
George Patani,Edmond J. LaVoie +1 more
TL;DR: This topic has been reviewed in previous years and the objective of this review is to provide an overview of bioisosteres that incorporates sufficient detail to enable the reader to understand the concepts being delineated.
Journal ArticleDOI
Synopsis of some recent tactical application of bioisosteres in drug design.
TL;DR: In this Perspective, some contemporary themes exploring the role of isosteres in drug design are sampled, with an emphasis placed on tactical applications designed to solve the kinds of problems that impinge on compound optimization and the long-term success of drug candidates.
Journal ArticleDOI
Antidepressant Drug Effects and Depression Severity: A Patient-Level Meta-analysis
Jay C. Fournier,Robert J. DeRubeis,Steven D. Hollon,Sona Dimidjian,Jay D. Amsterdam,Richard C. Shelton,Jan Fawcett +6 more
TL;DR: The magnitude of benefit of antidepressant medication compared with placebo increases with severity of depression symptoms and may be minimal or nonexistent, on average, in patients with mild or moderate symptoms.
Journal ArticleDOI
Metastasis: a question of life or death
Patrick Mehlen,Alain Puisieux +1 more
TL;DR: It is stressed that the inhibition of cell death, apart from its extensively described function in primary tumour development, is a crucial characteristic of metastatic cancer cells.