Journal ArticleDOI
2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult
Todd J. Anderson,Jean Grégoire,Glen J. Pearson,Arden R. Barry,Patrick Couture,Martin Dawes,Gordon A. Francis,Jacques Genest,Steven A. Grover,Milan Gupta,Milan Gupta,Robert A. Hegele,David C.W. Lau,Lawrence A. Leiter,Eva Lonn,G.B. John Mancini,Ruth McPherson,Daniel Ngui,Paul Poirier,John L. Sievenpiper,James A. Stone,George Thanassoulis,Richard Ward +22 more
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TLDR
Risk assessment and lipid determination should be considered in individuals older than 40 years of age or in those at increased risk regardless of age, and recommendation for the use of nonstatin medications is provided.About:
This article is published in Canadian Journal of Cardiology.The article was published on 2016-11-01. It has received 805 citations till now. The article focuses on the topics: Framingham Risk Score & Risk assessment.read more
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2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
Donna K. Arnett,Roger S. Blumenthal,Michelle A. Albert,Andrew B. Buroker,Zachary D. Goldberger,Ellen J. Hahn,Cheryl Dennison Himmelfarb,Amit Khera,Donald M. Lloyd-Jones,J. William McEvoy,Erin D. Michos,Michael D. Miedema,Daniel Muñoz,Sidney C. Smith,Salim S. Virani,Kim A. Williams,Joseph Yeboah,Boback Ziaeian +17 more
TL;DR: Patrick T. O’Gara, MD, MACC, FAHA, Chair Joshua A. Beckman,MD, MS, FAha, Chair-Elect Glenn N. Levine, MD., Immediate Past Chair Sana M. Al-Khatib, MD.
Journal ArticleDOI
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
Donna K. Arnett,Roger S. Blumenthal,Michelle A. Albert,Erin D. Michos,Andrew B. Buroker,Michael D. Miedema,Zachary D. Goldberger,Daniel Muñoz,Ellen J. Hahn,Sidney C. Smith,Cheryl Dennison Himmelfarb,Salim S. Virani,Amit Khera,Kim A. Williams,Donald M. Lloyd-Jones,Joseph Yeboah,J. William McEvoy,Boback Ziaeian,Aha Task Force Members,Patrick T. O'Gara,Joshua A. Beckman,Glenn N. Levine,Sana M. Al-Khatib,Mark A. Hlatky,Kim K. Birtcher,John S. Ikonomidis,Joaquin E. Cigarroa,Jose A. Joglar,Anita Deswal,Laura Mauri,Lee A. Fleisher,Mariann R. Piano,Federico Gentile,Barbara Riegel,Duminda N. Wijeysundera +34 more
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A Test in Context: Lipoprotein(a): Diagnosis, Prognosis, Controversies, and Emerging Therapies
TL;DR: This review summarizes the current landscape of Lp(a), discusses controversies, and reviews emerging therapies to reduce plasma Lp (a) levels to decrease risk of CVD and CAVS.
Journal ArticleDOI
Chronic Kidney Disease Diagnosis and Management: A Review
TL;DR: Optimal management of CKD includes cardiovascular risk reduction, treatment of albuminuria, avoidance of potential nephrotoxins, and adjustments to drug dosing (eg, many antibiotics and oral hypoglycemic agents).
Journal ArticleDOI
Effects of stress on the development and progression of cardiovascular disease
Mika Kivimäki,Andrew Steptoe +1 more
TL;DR: In real-life settings, mechanistic studies have corroborated earlier laboratory-based observations on stress-related pathophysiological changes that underlie triggering, such as lowered arrhythmic threshold and increased sympathetic activation with related increases in blood pressure, as well as pro-inflammatory and procoagulant responses.
References
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Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Salim Yusuf,Steven Hawken,Stephanie Ôunpuu,Tony Dans,Alvaro Avezum,Fernando Lanas,Matthew J. McQueen,Andrzej Budaj,Prem Pais,John Varigos,Liu Lisheng +10 more
TL;DR: Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
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Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
Anders G. Olsson,Jjv McMurray,Gudmundur Thorgeirsson,C Spaulding,J Slattery,Kalevi Pyörälä,Ole Faergeman,RA Wright,Kåre Berg,Lars Wilhelmsen,Terje R. Pedersen,Tatu A. Miettinen,Harvey D. White,John Kjekshus,Michael Gnant +14 more
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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group
J. Shepherd,Stuart M. Cobbe,Ian Ford,C. G. Isles,AR Lorimer,Peter W. Macfarlane,J. H. Mckillop,Christopher J. Packard +7 more
TL;DR: Treatment with pravastatin significantly reduced the incidence of myocardial infarction and death from cardiovascular causes without adversely affecting the risk of death from noncardiovascular causes in men with moderate hypercholesterolemia and no history of my Cardiac Infarction.
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Health benefits of physical activity: the evidence
TL;DR: It is revealed that the current Health Canada physical activity guidelines are sufficient to elicit health benefits, especially in previously sedentary people, and that a further increase in physical activity and fitness will lead to additional improvements in health status.
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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals: a randomised placebo-controlled trial. Commentary
TL;DR: Adding simvastatin to existing treatments safely produces substantial additional benefits for a wide range of high-risk patients, irrespective of their initial cholesterol concentrations.
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