Book ChapterDOI
81 – Structure and Development of Alveolar Epithelial Cells
Henry J. Rozycki,Karen D. Hendricks-Muñoz +1 more
- pp 809-813
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The article was published on 2017-01-01. It has received 1 citations till now. The article focuses on the topics: A549 cell.read more
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Journal ArticleDOI
Transcriptional regulation of cell shape during organ morphogenesis
TL;DR: This review highlights the essential role of transcriptional regulation of cell shape during morphogenesis of the heart, lungs, gastrointestinal tract, and kidneys and emphasizes the evolutionary conservation of these processes across different model organisms.
References
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Journal ArticleDOI
Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer
Carla F. Kim,Erica L. Jackson,Amber Woolfenden,Sharon Lawrence,Imran Babar,Sinae Vogel,Denise Crowley,Roderick T. Bronson,Tyler Jacks +8 more
TL;DR: Although bronchiolar cells and alveolar cells are proposed to be the precursor cells of adenocarcinoma, this work points to bronchioalveolar stem cells as the putative cells of origin for this subtype of lung cancer.
Journal ArticleDOI
Alveolar macrophages: plasticity in a tissue-specific context
Tracy Hussell,Thomas J. Bell +1 more
TL;DR: The unique tissue location and function of alveolarmacrophages distinguish them from other macrophage populations and suggest that it is important to classify macrophages according to the site that they occupy.
Journal ArticleDOI
Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development
TL;DR: Many gaps remain in knowledge, the filling of which is essential for understanding respiratory disorders, congenital defects in human neonates, and how the disruption of morphogenetic programs early in lung development can lead to deficiencies that persist throughout life.
Journal ArticleDOI
Alveolar progenitor and stem cells in lung development, renewal and cancer
TL;DR: There is a switch after birth, when AT2 cells function as stem cells that contribute to alveolar renewal, repair and cancer, and it is proposed that local signals regulate AT2 stem-cell activity.
Journal ArticleDOI
The Role of Scgb1a1+ Clara Cells in the Long-Term Maintenance and Repair of Lung Airway, but Not Alveolar, Epithelium
Emma L. Rawlins,Tadashi Okubo,Yan Xue,David M. Brass,Richard L. Auten,Hiroshi Hasegawa,Fan Wang,Brigid L.M. Hogan +7 more
TL;DR: The results support a model in which the trachea, bronchioles, and alveoli are maintained by distinct populations of epithelial progenitor cells.