A 2011 Survey of Clinical Practice Patterns in the Management of Graves' Disease
TLDR
Current practices in the management of GD diverge in some areas from recently published guidelines; these differences should be assessed serially to determine the impact of the guidelines on future clinical practice.Abstract:
Context: More than two decades have passed since members from the American Thyroid Association (ATA), European Thyroid Association, and Japan Thyroid Association were surveyed on management practices for patients with hyperthyroidism due to Graves' disease (GD). Objective: We sought to document current practices in the management of GD and compare these results both to those documented in earlier surveys and to practice recommendations made in the 2011 ATA/American Association of Clinical Endocrinologists (AACE) hyperthyroidism practice guidelines. Lastly, we sought to examine differences in GD management among international members of U.S.-based endocrine societies. Methods: Members of The Endocrine Society (TES), ATA, and AACE were invited to participate in a web-based survey dealing with testing, treatment preference, and modulating factors in patients with GD. Results: A total of 730 respondents participated in the survey, 696 of whom completed all sections. Respondents included 641 TES members, 330 A...read more
Citations
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Journal ArticleDOI
2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis
Douglas S. Ross,Henry B. Burch,David S. Cooper,M. Carol Greenlee,Peter Laurberg,Ana Luiza Maia,Scott A. Rivkees,Mary H. Samuels,Julie Ann Sosa,Marius N. Stan,Martin A. Walter +10 more
TL;DR: One hundred twenty-four evidence-based recommendations were developed to aid in the care of patients with thyrotoxicosis and to share what the task force believes is current, rational, and optimal medical practice.
Journal ArticleDOI
2018 European Thyroid Association Guideline for the Management of Graves' Hyperthyroidism
TL;DR: If a patient relapses after completing a course of ATD, definitive treatment is recommended; however, continued long-term low-dose MMI can be considered, and steroid prophylaxis is warranted in Graves’ patients with mild/active orbitopathy receiving RAI.
Journal ArticleDOI
The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults
Kepal N. Patel,Linwah Yip,Carrie C. Lubitz,Elizabeth G. Grubbs,Barbra S. Miller,Wen T. Shen,Peter Angelos,Herbert Chen,Gerard M. Doherty,Thomas J. Fahey,Electron Kebebew,Virginia A. LiVolsi,Nancy D. Perrier,Jennifer A. Sipos,Julie Ann Sosa,David L. Steward,Ralph P. Tufano,Christopher R. McHenry,Sally E. Carty +18 more
TL;DR: These clinical guidelines analyze the indications for thyroidectomy as well as its definitions, technique, morbidity, and outcomes and were created to assist clinicians in the optimal surgical management of thyroid disease.
Journal ArticleDOI
Management of Graves Disease: A Review
TL;DR: Management of Graves disease includes treatment with antithyroid drugs, RAI, or thyroidectomy, and Physicians should be familiar with the advantages and disadvantages of each therapy to best counsel their patients.
Journal ArticleDOI
Hyperthyroidism in pregnancy
David S. Cooper,Peter Laurberg +1 more
TL;DR: Physiological and pathophysiological changes in thyroid hormone economy in pregnancy, the diagnosis and management of hyperthyroidism during pregnancy, severe life-threatening thyrotoxicosis inregnancy, neonatal thy rotoxicosis, and post-partum hyperthy thyroiditis are discussed.
References
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Journal ArticleDOI
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum
Erik K. Alexander,Elizabeth N. Pearce,Gregory A. Brent,Rosalind S. Brown,Herbert Chen,Chrysoula Dosiou,William A. Grobman,Peter Laurberg,John Lazarus,Susan J. Mandel,Robin P. Peeters,Scott Sullivan +11 more
TL;DR: The revised guidelines for the management of thyroid disease in pregnancy include recommendations regarding the interpretation of thyroid function tests in pregnancy, iodine nutrition, thyroid autoantibodies and pregnancy complications, thyroid considerations in infertile women, hypothyroidism in pregnancy and thyrotoxicosis in pregnancy.
Journal ArticleDOI
The spectrum of thyroid disease in a community: the whickham survey
W.M.G. Tunbridge,D. C. Evered,Reginald Hall,D. Appleton,M Brewis,F. Clark,J G Evans,E. T. Young,T. Bird,P. A. Smith +9 more
TL;DR: TSH levels above 6 mu/1 were shown to reflect a significant lowering of circulating thyroxine levels and showed a strong association with thyroid antibodies in both sexes, independent of age.
Journal ArticleDOI
Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists
Rebecca S. Bahn,Henry B. Burch,David S. Cooper,Jeffrey R. Garber,M. Carol Greenlee,Irwin Klein,Peter Laurberg,I. Ross McDougall,Victor M. Montori,Scott A. Rivkees,Douglas S. Ross,Julie Ann Sosa,Marius N. Stan +12 more
TL;DR: Evidence-based clinical guidelines for the management of thyrotoxicosis are described that would be useful to generalist and subspeciality physicians and others providing care for patients with this condition.
Journal ArticleDOI
Relation between therapy for hyperthyroidism and the course of Graves' ophthalmopathy.
Luigi Bartalena,Claudio Marcocci,Fausto Bogazzi,Luca Manetti,Maria Laura Tanda,Enrica Dell'Unto,G. Bruno-Bossio,Marco Nardi,Maria Pia Bartolomei,A Lepri,Giuseppe Rossi,Enio Martino,Aldo Pinchera +12 more
TL;DR: Radioiodine therapy for Graves' hyperthyroidism is followed by the appearance or worsening of ophthalmopathy more often than is therapy with methimazole, and this can be prevented by the administration of prednisone.
Journal ArticleDOI
Pathogenesis of Graves' ophthalmopathy.
TL;DR: Once initiated, the orbital immune process frequently takes on a momentum of its own, leading to non-specific but nonetheless harmful consequences such as tissue hypoxia, oxygen free radical damage and fibrogenic tissue remodeling.