Journal ArticleDOI
A Comparison of Quality of Life Scores in Patients With Angina Pectoris After Angioplasty Compared With After Medical Therapy Outcomes of a Randomized Clinical Trial
TLDR
In this article, the authors compared the impact of percutaneous transluminal coronary angioplasty (PTCA) and medical therapy in patients with angina pectoris.Abstract:
Background Evaluations of therapy for the treatment of angina have traditionally consisted of a combination of objective measures, such as exercise tolerance, and subjective markers, such as angina attack rate. Recently, the need to assess “how patients feel”—their quality of life (QOL)—has been regarded with increasing importance. Standard instruments are available to assess QOL and its change after therapeutic intervention. Although QOL instruments have been used to assess the efficacy of percutaneous transluminal coronary angioplasty (PTCA), they have not been used previously to compare the impact of PTCA with that of medical therapy in patients with angina pectoris. We report on the changes in self-assessed QOL among patients randomly assigned to treatment by PTCA or medical therapy and relate these measurements to changes in exercise performance and coronary angiograms. Methods and Results Patients with stable angina, a positive exercise tolerance test, and at least 70% stenosis (index lesion) in the...read more
Citations
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Journal ArticleDOI
Effect of PCI on Quality of Life in Patients with Stable Coronary Disease
William S. Weintraub,John A. Spertus,Paul Kolm,David J. Maron,Zefeng Zhang,Claudine Jurkovitz,Wei Zhang,Pamela M. Hartigan,Cheryl Lewis,Emir Veledar,James M. Bowen,Sandra B. Dunbar,Christi Deaton,Stanley E. Kaufman,Robert A. O'Rourke,Ron Goeree,Paul G. Barnett,Koon K. Teo,William E. Boden +18 more
TL;DR: Among patients with stable angina, both thosetreated with PCI and those treated with optimal medical therapy alone had marked improvements in health status during follow-up, and similar incremental benefits from PCI were seen in some but not all RAND-36 domains.
Journal ArticleDOI
Trial of invasive versus medical therapy in elderly patients with chronic symptomatic coronary-artery disease (TIME): a randomised trial.
TL;DR: Patients aged 75 years or older with angina despite standard drug therapy benefit more from revascularisation than from optimised medical therapy in terms of symptom relief and quality of life.
Journal ArticleDOI
Exercise training intervention after coronary angioplasty: the ETICA trial ☆
Romualdo Belardinelli,Ivana Paolini,G Cianci,Roberto Piva,Demetrios Georgiou,Augusto Purcaro +5 more
TL;DR: Moderate ET improves functional capacity and QOL after PTCA or CS and during the follow-up, trained patients had fewer events and a lower hospital readmission rate than controls, despite an unchanged restenosis rate.
Journal ArticleDOI
A Comparison of Coronary-Artery Stenting with Angioplasty for Isolated Stenosis of the Proximal Left Anterior Descending Coronary Artery
Francesco Versaci,Achille Gaspardone,Fabrizio Tomai,Filippo Crea,Luigi Chiariello,Pier A. Gioffrè +5 more
TL;DR: In patients with symptomatic isolated stenosis of the proximal left anterior descending coronary artery, stenting had advantages over standard coronary angioplasty in that it was associated with both a lower rate of restenosis and a better clinical outcome.
Journal ArticleDOI
Outcome of elderly patients with chronic symptomatic coronary artery disease with an invasive vs optimized medical treatment strategy: one-year results of the randomized TIME trial.
Matthias Pfisterer,Peter Buser,Stefan Osswald,Urs Allemann,Wolfgang Amann,Walter Angehrn,Eric Eeckhout,Paul Erne,Werner Estlinbaum,Gabriela M. Kuster,Tiziano Moccetti,Barbara Naegeli,Peter Rickenbacher +12 more
TL;DR: 1-year outcomes in elderly patients with chronic angina are similar with regard to symptoms, quality of life, and death or nonfatal infarction with invasive vs optimized medical strategies based on this intention-to-treat analysis.
References
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Journal ArticleDOI
Measuring health-related quality of life.
TL;DR: Patients, clinicians, and health care administrators are all keenly interested in the effects of medical interventions on HRQL, because increasing efforts exist to incorporate HRQLs as measures of the quality of care and of clinical effectiveness, and because payers are beginning to use HRQL information in reimbursement decisions.
Journal ArticleDOI
A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators.
TL;DR: For patients with single-vessel coronary artery disease, PTCA offers earlier and more complete relief of angina than medical therapy and is associated with better performance on the exercise test.
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