Journal ArticleDOI
A new antibacterial chromone derivative from mangrove-derived fungus Penicillium aculeatum (No. 9EB).
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TLDR
One new chromone derivative, (2ʹS*)-2-(2-hydroxypropyl)-5-methyl-7, 8-dihydroxy-chromone, together with three known compounds, bacillisporin A, bacsporin B and 5-carboxyphthalide were obtained from the mangrove-derived fungus Penicillium aculeatum by the detailed analysis of comprehensive spectroscopic data.About:
This article is published in Natural Product Research.The article was published on 2017-02-01. It has received 23 citations till now. The article focuses on the topics: Chromone & Derivative (chemistry).read more
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Journal ArticleDOI
Secondary Metabolites of Mangrove-Associated Strains of Talaromyces
TL;DR: The present paper offers a review of the research on the characterization and biological activities of secondary metabolites from manglicolous strains of species belonging to the genus Talaromyces and considers the opportunity for a more reliable identification of this biological material in the light of recent taxonomic revisions.
Journal ArticleDOI
Recent progress of antibacterial natural products: Future antibiotics candidates.
Jiangkun Dai,Jiangkun Dai,Jiangkun Dai,Rui Han,Yujie Xu,Na Li,Junru Wang,Wenjia Dan,Wenjia Dan +8 more
TL;DR: 256 natural products from 11 structural classes in the period of 2016-01/2020 selected by SciFinder with new compounds or new structures and MICs lower than 10 μg/mL or 10 μM as criterions will provide some effective antibacterial lead compounds for medicinal chemists.
Journal ArticleDOI
Marine Pharmacology in 2016-2017: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.
Alejandro M. S. Mayer,Aimee J Guerrero,Abimael D. Rodríguez,Orazio Taglialatela-Scafati,Fumiaki Nakamura,Nobuhiro Fusetani +5 more
TL;DR: In 2016–2017, the preclinical marine natural product pharmacology pipeline generated both novel pharmacology as well as potentially new lead compounds for the growing clinical marine pharmaceutical pipeline, and thus sustained with its contributions the global research for novel and effective therapeutic strategies for multiple disease categories.
Journal ArticleDOI
Human health-related properties of chromones: an overview
Amirhossein Nazhand,Alessandra Durazzo,Massimo Lucarini,Raffaele Romano,Maria Alessandra Mobilia,Angelo A. Izzo,Antonello Santini +6 more
TL;DR: The biological and pharmacological performance of chromones, including their anti-inflammatory, anticancer, anti-oxidant, and anti-microbial activities are scanned.
Journal ArticleDOI
Fungal Diversity in Intertidal Mudflats and Abandoned Solar Salterns as a Source for Biological Resources.
Young Mok Heo,Hanbyul Lee,Kyeongwon Kim,Sun Lul Kwon,Min Young Park,Ji Eun Kang,Gyu Hyeok Kim,Beom Seok Kim,Jae Jin Kim +8 more
TL;DR: This study provides reliable fungal diversity information for mudflats and abandoned salterns and shows that they are highly valuable for bioprospecting not only for novel microorganisms but also for novel bioactive compounds.
References
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Journal ArticleDOI
Marine natural products.
TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
Journal ArticleDOI
A simple and reproducible 96 well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing
Christopher G. Pierce,Priya Uppuluri,Amanda R Tristan,Floyd L. Wormley,Eilidh Mowat,Gordon Ramage,Jose L. Lopez-Ribot +6 more
TL;DR: This technique simplifies biofilm formation and quantification, making it more reliable and comparable among different laboratories, a necessary step toward the standardization of antifungal susceptibility testing of biofilms.
Journal ArticleDOI
Exploring marine resources for bioactive compounds.
Paula Kiuru,M. Valeria DʼAuria,Christian D. Muller,Päivi Tammela,Heikki Vuorela,Jari Yli-Kauhaluoma +5 more
TL;DR: Marine research is expected to offer novel marine-based lead compounds for industries and strengthen their product portfolios related to pharmaceutical, nutraceutical, cosmetic, food processing, material and biosensor applications.
Journal ArticleDOI
Asperterpenoid A, a New Sesterterpenoid as an Inhibitor of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B from the Culture of Aspergillus sp. 16-5c
Xishan Huang,Hongbo Huang,Hanxiang Li,Xuefeng Sun,Huarong Huang,Yongjun Lu,Yongcheng Lin,Yuhua Long,Zhigang She +8 more
TL;DR: Asperterpenoid A exhibited strong inhibitory activity against Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) with an IC(50) value of 2.2 μM.
Journal ArticleDOI
Asperterpenols A and B, new sesterterpenoids isolated from a mangrove endophytic fungus Aspergillus sp. 085242.
Ze'en Xiao,Huarong Huang,Chang-Lun Shao,Xuekui Xia,Lin Ma,Xishan Huang,Yongjun Lu,Yongcheng Lin,Yuhua Long,Zhigang She +9 more
TL;DR: Two novel sesterterpenoids with an unusual 5/8/6/6 tetracyclic ring skeleton were isolated from a mangrove endophytic fungus Aspergillus sp.