Journal ArticleDOI
A Simple, Efficient and Green Procedure for the Knoevenagel Condensation of Aldehydes with N-Methylpiperazine at Room Temperature under Solvent-Free Conditions
Chhanda Mukhopadhyay,Arup Datta +1 more
TLDR
In this article, Knoevenagel condensation of aromatic, aliphatic, and heteroaromatic aldehydes with active methylene compounds such as ethylcyanoacetate, malononitrile, and cyanoacetamide proceed very smoothly at room temperature by simply mixing the ingredients together under solvent-free conditions.About:
This article is published in Synthetic Communications.The article was published on 2008-08-18. It has received 35 citations till now. The article focuses on the topics: Knoevenagel condensation & Malononitrile.read more
Citations
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Journal ArticleDOI
Efficient and reusable amine-functionalized polyacrylonitrile fiber catalysts for Knoevenagel condensation in water
Guowei Li,Jia Xiao,Wenqin Zhang +2 more
TL;DR: A series of new fiber catalysts has been synthesized by aminating a commercially available polyacrylonitrile fiber with polyamines such as diethylenetriamine and triethylenetetramine as discussed by the authors.
Journal ArticleDOI
Rapid and efficient Knoevenagel condensation catalyzed by a novel protic ionic liquid under ultrasonic irradiation
TL;DR: An efficient and reusable protic-ionic-liquid solvent-catalyst system, HMTA-AcOH-H2O, has been developed and used in the Knoevenagel condensation reaction of aromatic aldehydes with ethyl 2-cyanoacetate as discussed by the authors.
Journal ArticleDOI
Synthesis of 3-(2-furylmethylene)-2,4-pentanedione using DL-Alanine functionalized MCM-41 catalyst via Knoevenagel condensation reaction
TL;DR: In this article, an alanine functionalized MCM-41 (Alanine-MCM41) was used as a solid base catalysts for the Knoevenagel condensation of furfural and acetylacetone under solvent free condition.
Journal ArticleDOI
Green and efficient Knoevenagel condensation catalysed by a DBU based ionic liquid in water
TL;DR: An efficient and facile protocol for the Knoevenagel condensation of aromatic aldehydes with active methylene compounds with task specific ionic liquid 1,8-diazabicyclo[5.4.0]-undec-... was proposed in this paper.
Journal ArticleDOI
A new silica based substituted piperidine derivative catalyzed expeditious room temperature synthesis of homo and hetero bis-Knoevenagel condensation products
Chhanda Mukhopadhyay,Suman Ray +1 more
TL;DR: In this paper, a new silica based piperidine derivative has been designed, synthesized and characterized by solid state carbon 13 CP MAS NMR, BET surface area analysis, IR, TGA studies, elemental analysis and pH experiment.
References
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Journal ArticleDOI
Efficient Green Procedure for the Knoevenagel Condensation under Solvent‐Free Conditions
TL;DR: In this article, Knoevenagel condensation of aromatic aldehydes with active methylene compounds under solvent free conditions to synthesize arylidene compounds by grinding in the presence of TEBA at room temperature has been described.
Journal ArticleDOI
Traceless solid-phase synthesis of 2-amino-5-alkylidene-thiazol-4-ones
TL;DR: In this article, 2-Amino-5-alkylidene-thiazol-4-ones bearing two diversity points are prepared by a solid-phase strategy exploiting rhodanine as the starting material.
Journal ArticleDOI
A Practical Knoevenagel Condensation Catalyzed by PEG400 and Anhydrous K2CO3 Without Solvent
TL;DR: In this article, the condensation of aromatic aldehydes with active methylene compounds under solvent-free conditions to synthesize arylidene compounds in good to excellent yields using powdered anhydrous K2CO3 and PEG400 as catalysts has been described.
Journal ArticleDOI
Solvent-free bentonite-catalyzed condensation of malonic acid and aromatic aldehydes under microwave irradiation
TL;DR: In this article, the condensation between malonic acid and aromatic aldehydes was studied in the presence of bentonite and various diacids were prepared in good yields and in very short reaction times under microwave irradiation.
Related Papers (5)
Ionic Liquid as Catalyst and Reaction Medium – A Simple, Efficient and Green Procedure for Knoevenagel Condensation of Aliphatic and Aromatic Carbonyl Compounds Using a Task‐Specific Basic Ionic Liquid
Brindaban C. Ranu,Ranjan Jana +1 more