Journal ArticleDOI
A Systematic Review and Meta-analysis of Survival and Surgical Outcomes Following Neoadjuvant Chemoradiotherapy for Pancreatic Cancer
Jerome M. Laurence,Jerome M. Laurence,Jerome M. Laurence,Peter Duy Tran,Kavita Morarji,Guy D. Eslick,Vincent W. T. Lam,Vincent W. T. Lam,Charbel Sandroussi,Charbel Sandroussi +9 more
TLDR
The meta-analysis found that patients with unresectable pancreatic cancer who underwent neoadjuvant chemoradiotherapy achieved similar survival outcomes to patients with resectable disease, even though only 40% were ultimately resected.About:
This article is published in Journal of Gastrointestinal Surgery.The article was published on 2011-09-13. It has received 122 citations till now. The article focuses on the topics: Chemoradiotherapy & Pancreatic fistula.read more
Citations
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Recent Progress in Pancreatic Cancer
Christopher L. Wolfgang,Joseph M. Herman,Daniel A. Laheru,Alison P. Klein,Michael A. Erdek,Elliot K. Fishman,Ralph H. Hruban +6 more
TL;DR: In this paper, it is shown that multidisciplinary care that provides comprehensive and coordinated evaluation and treatment is the most effective way to manage patients with pancreatic cancer, and it is clear that multi-disciplinary care is the best way to care for patients.
Journal ArticleDOI
Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS).
Maximilian Bockhorn,Faik G. Uzunoglu,Mustapha Adham,Clem W. Imrie,Miroslav Milicevic,Aken A. Sandberg,Horacio J. Asbun,Claudio Bassi,Markus W. Büchler,Richard Charnley,Kevin C. Conlon,Laureano Fernandez Cruz,Christos Dervenis,Abe Fingerhutt,Helmut Friess,Dirk J. Gouma,Werner Hartwig,Keith D. Lillemoe,Marco Montorsi,John P. Neoptolemos,Shailesh V. Shrikhande,Kyoichi Takaori,William Traverso,Yogesh K. Vashist,Charles M. Vollmer,Charles J. Yeo,Jakob R. Izbicki +26 more
TL;DR: Current evidence justifies portomesenteric venous resection in patients with BRPC, and a new classification of extrahepatic mesentericoportal ven Mous resections is proposed by the ISGPS.
Journal ArticleDOI
Meta-analysis comparing upfront surgery with neoadjuvant treatment in patients with resectable or borderline resectable pancreatic cancer.
Eva Versteijne,J.A. Vogel,Marc G. Besselink,O.R.C. Busch,Johanna W. Wilmink,Joost G. Daams,C.H.J. van Eijck,B. Groot Koerkamp,Coen R.N. Rasch,G. van Tienhoven +9 more
TL;DR: The aim of this study was to report survival by intention to treat in a comparison of upfront surgery versus neoadjuvant treatment in resectables or borderline resectable pancreatic cancer.
Journal ArticleDOI
Pancreatic Adenocarcinoma, Version 2.2014
Margaret A. Tempero,Mokenge P. Malafa,Stephen W. Behrman,Al B. Benson,Ephraim S. Casper,E. Gabriela Chiorean,Vincent Chung,Steven J. Cohen,Brian G. Czito,Anitra Engebretson,Mary Feng,William G. Hawkins,Joseph M. Herman,John P. Hoffman,Andrew H. Ko,Srinadh Komanduri,Albert C. Koong,Andrew M. Lowy,Wen Wee Ma,Nipun B. Merchant,Sean J. Mulvihill,Peter Muscarella,Eric K. Nakakura,Jorge Obando,Martha B. Pitman,Sushanth Reddy,Aaron R. Sasson,Sarah P. Thayer,Colin D. Weekes,Robert A. Wolff,Brian M. Wolpin,Jennifer L. Burns,Deborah A. Freedman-Cass +32 more
TL;DR: These NCCN Guidelines Insights summarize major discussion points from the 2014 NCCn Pancreatic Adenocarcinoma Panel meeting, which focused mainly on the management of borderline resectable and locally advanced disease.
Journal Article
Pancreatic adenocarcinoma, version 2.2012
Margaret A. Tempero,J. Pablo Arnoletti,Stephen W. Behrman,Edgar Ben-Josef,Al B. Benson,Ephraim S. Casper,Steven J. Cohen,Brian G. Czito,Joshua D. I. Ellenhorn,William G. Hawkins,Joseph M. Herman,John P. Hoffman,Andrew H. Ko,Srinadh Komanduri,Albert C. Koong,Wen Wee Ma,Mokenge P. Malafa,Nipun B. Merchant,Sean J. Mulvihill,Peter Muscarella,Eric K. Nakakura,Jorge Obando,Martha B. Pitman,Aaron R. Sasson,Anitra Tally,Sarah P. Thayer,Samuel H. Whiting,Robert A. Wolff,Brian M. Wolpin,Deborah A. Freedman-Cass,Dorothy A. Shead +30 more
References
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Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Journal ArticleDOI
Cancer statistics, 2010
TL;DR: The American Cancer Society as mentioned in this paper estimated the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data regarding cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from National Center for Health Statistics.
Journal ArticleDOI
Practical methods for incorporating summary time-to-event data into meta-analysis
TL;DR: This practical guide should improve the quality of the analysis and subsequent interpretation of systematic reviews and meta-analyses that include time-to-event outcomes and provide a corresponding, easy- to-use calculations spreadsheet, to facilitate the computational aspects.
Journal ArticleDOI
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints.
TL;DR: A number of methods of extracting estimates of the log hazard ratio and its variance in a variety of situations are presented to improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints.
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