scispace - formally typeset
Patent

Albumin Fusion Proteins

Reads0
Chats0
TLDR
The present invention encompasses albumin fusion proteins as discussed by the authors, as well as vectors containing these nucleic acids, host cells transformed with the nucleic acid vectors, and methods of making the fusion proteins of the invention.
Abstract
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention.

read more

Citations
More filters
Patent

Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same

TL;DR: In this paper, the present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polyptides, and vectors and host cells comprising those nucleic amino acid sequences.
PatentDOI

Costimulatory b7-h1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target

TL;DR: In this article, the authors present methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7H1-receptor interaction, and methods of selecting candidate subjects likely to benefit from cancer immunotherapy.
Patent

Anti-pd-l1 antibodies and their use to enhance t-cell function

TL;DR: In this paper, anti-PD-L1 antibodies are used to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
Patent

IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME

TL;DR: In this article, a variant Fc region comprising at least one amino acid modification relative to a wild-type Fc regions was proposed, which was used for the treatment or prevention of a disease or disorder where an enhanced efficacy of effector cell function mediated by FcγR is desired.
Patent

Compositions and methods for the diagnosis and treatment of tumor

TL;DR: In this article, an antibody drug conjugate composition of matter useful for the diagnosis and treatment of tumors in mammals and methods of using those compositions of matter for the same were described.
References
More filters
Book

Molecular Cloning: A Laboratory Manual

TL;DR: Molecular Cloning has served as the foundation of technical expertise in labs worldwide for 30 years as mentioned in this paper and has been so popular, or so influential, that no other manual has been more widely used and influential.
Book

Antibodies: A Laboratory Manual

Ed Harlow, +1 more
TL;DR: A second edition of Antibodies: A Laboratory Manual is being published in September 2013, Revised, extended and updated by Edward Greenfield of the Dana-Farber Cancer Center, the material has been recast with extensive new information and new chapters have been added.
Book

Current protocols in immunology

TL;DR: Current Protocols in Immunology is a three-volume looseleaf manual that provides comprehensive coverage of immunological methods from classic to the most cutting edge, including antibody detection and preparation, assays for functional activities of mouse and human cells involved in immune responses, and animal models of autoimmune and inflammatory diseases.
Book

Molecular Cell Biology

TL;DR: Molecular cell biology, Molecular cell biology , مرکز فناوری اطلاعات و اصاع رسانی, کδاوρزی
Related Papers (5)