Journal ArticleDOI
An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release
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TLDR
The doped rare earths endow the platform with dual-modal up-conversion luminescent (UCL) and computer tomography (CT) imaging properties, thus achieving the target of imaging-guided synergistic therapy under by a single NIR light.About:
This article is published in Biomaterials.The article was published on 2015-09-01. It has received 186 citations till now. The article focuses on the topics: Photothermal therapy & Photothermal effect.read more
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Nanotechnology for Multimodal Synergistic Cancer Therapy
TL;DR: In this review, state-of-the-art studies concerning recent advances in nanotechnology-mediated multimodal synergistic therapy will be systematically discussed, with an emphasis on the construction of multifunctional nanomaterials for realizing bimodal and trimodal synergy therapy.
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Black Phosphorus Nanosheet‐Based Drug Delivery System for Synergistic Photodynamic/Photothermal/Chemotherapy of Cancer
Wansong Chen,Jiang Ouyang,Hong Liu,Min Chen,Ke Zeng,Jianping Sheng,Zhenjun Liu,Yajing Han,Liqiang Wang,Juan Li,Liu Deng,You-Nian Liu,Shaojun Guo +12 more
TL;DR: The synergistic photodynamic/photothermal/chemotherapy makes BP-based drug delivery system a multifunctional nanomedicine platform, and the intrinsic photothermal and photodynamic effects of BP enhance the antitumor activities.
Journal ArticleDOI
Recent advances in functional nanomaterials for light–triggered cancer therapy
TL;DR: An in–depth review of major breakthroughs in recent advanced functional nanomaterials for photo–triggered therapy is presented, and an outlook of the future directions of the rapidly growing functional nanomechanical directions is given.
Journal ArticleDOI
Nanomaterials as photothermal therapeutic agents.
TL;DR: This review article summarizes the current status of employing nanomaterials with photothermal effects for anti-cancer treatment and Mechanisms of the photothermal effect and various factors affecting photothermal performance will be discussed.
Journal ArticleDOI
Precise nanomedicine for intelligent therapy of cancer
Huabing Chen,Zhanjun Gu,An Hongwei,An Hongwei,Chunying Chen,Chunying Chen,Jie Chen,Jie Chen,Ran Cui,Siqin Chen,Wei-Hai Chen,Xuesi Chen,Xuesi Chen,Xiaoyuan Chen,Zhuo Chen,Baoquan Ding,Qian Dong,Qin Fan,Ting Fu,Da-Yong Hou,Qiao Jiang,Hengte Ke,Xiqun Jiang,Gang Liu,Suping Li,Tianyu Li,Zhuang Liu,Guangjun Nie,Muhammad Ovais,Muhammad Ovais,Dai-Wen Pang,Nasha Qiu,Youqing Shen,Huayu Tian,Huayu Tian,Chao Wang,Hao Wang,Zi-Qi Wang,Huaping Xu,Jiang Fei Xu,Xiangliang Yang,Shuang Zhu,Xianchuang Zheng,Xian-Zheng Zhang,Yanbing Zhao,Weihong Tan,Weihong Tan,Xi Zhang,Yuliang Zhao +48 more
TL;DR: The recent advances of intelligent cancer nanomedicine are demonstrated, and the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanotechine including various imaging and therapeutic applications, as well as nanotoxicity is discussed.
References
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Journal ArticleDOI
Thermo- and pH-responsive polymers in drug delivery.
TL;DR: The majority of examples, discussed in this paper, deal with pH-responsive drug delivery system, and Thermo-responsive polymer is also covered to a large extent, as well as double-responsive system.
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Upconversion nanophosphors for small-animal imaging
Jing Zhou,Zhuang Liu,Fuyou Li +2 more
TL;DR: In this critical review, recent reports regarding the synthesis of water-soluble UCNPs and their surface modification and bioconjugation chemistry are summarized and the applications ofUCNPs for small-animal imaging, including tumor-targeted imaging, lymphatic imaging, vascular imaging and cell tracking are reviewed in detail.
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Upconversion nanoparticles in biological labeling, imaging, and therapy
TL;DR: Recent developments in optical biolabeling and bio-imaging involving upconversion nanoparticles are reviewed, simultaneously bringing to the forefront the desirable characteristics, strengths and weaknesses of these luminescent nanomaterials.
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Recent Progress in Rare Earth Micro/Nanocrystals: Soft Chemical Synthesis, Luminescent Properties, and Biomedical Applications
TL;DR: Synthesis, Luminescent Properties, and Biomedical Applications Shili Gai,‡ Chunxia Li,† Piaoping Yang,*,‡ and Jun Lin*,† † state Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.
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Nanoparticles in photodynamic therapy: an emerging paradigm.
TL;DR: A functional classification for nanoparticles in PDT is introduced to divide them into passive carriers and active participants in photosensitizer excitation, and these active or second-generation PDT nanoparticles probably offer the best hope for extending the reach of PDT to regions deep in the body.