Andrographolide engineered gold nanoparticle to overcome drug resistant visceral leishmaniasis.
Suvadra Das,Asim Halder,Saptarshi Mandal,Mohammad A. Jafar Mazumder,Tanmoy Bera,Arup Mukherjee,Partha Roy +6 more
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TLDR
This study aims to arrive at terpenoid andrographolide engineered gold nanoparticle (AGAunps) facile synthesis and its efficacy evaluations against wild and drug resistant VL strains for the first time.Abstract:
Visceral leishmaniasis (VL) is World Health Organization designated most serious leishmaniasis with an annual mortality rate of 50,000. Even after country specific eradication programs, the disease...read more
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7,8-dihydroxyflavone-functionalized gold nanoparticles target the arginase enzyme of Leishmania donovani.
Pragya Prasanna,Prakash Kumar,Saptarshi Mandal,Tanvi Payal,Saurabh Kumar,Sk. Ugir Hossain,Prolay Das,V Ravichandiran,Debabrata Mandal +8 more
TL;DR: In this article, the efficacy and possible mechanism of action of 7,8-dihydroxyflavone (DHF) and DHF synthesized gold nanoparticles (GNPs) against the parasite Leishmania donovani were analyzed.
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The Adroitness of Andrographolide as a Natural Weapon Against Colorectal Cancer.
TL;DR: In this article, the authors provided an overview of the importance of one such medicinal herb of Chinese and Indian origin: Andrographis paniculate on colorectal cancer with special emphasis on its principal bioactive component andrographolide (AGP) and its underlying mechanisms of action.
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Biofunctionalized silver and gold nanoparticles as potential curative agents
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Metallic Nanoparticles: A New Frontier in the Fight Against Leishmaniasis.
Rhanoica Oliveira Guerra,José Rodrigues do Carmo Neto,Tarcísio de Albuquerque Martins,Thais S. Farnesi-de-Assunção,Virmondes Rodrigues Junior,Carlo José Freire de Oliveira,Anielle Christine Almeida Silva,Marcos Vinicius da Silva +7 more
TL;DR: This review explores the progress of the use of metallic nanoparticles as a new tool in the treatment of leishmaniasis, as well as discusses the gaps in knowledge that need to be addressed to consolidate a safe, effective, and definitive therapeutic intervention against these infections.
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Phytochemical-conjugated bio-safe gold nanoparticles in breast cancer: a comprehensive update
TL;DR: This review marks the first attempt to explore the potential of phytochemical-derived nano-gold in breast cancer treatment by exploring diverse phytochemicals-based synthesis routes to arrive at nano-dimensional gold with spotlight on reaction mechanisms, reaction variables, specific advantages, toxicity and their influence in Breast cancer conditions.
References
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Green synthesis of metal nanoparticles using plants
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