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Angiogenesis: from plants to blood vessels

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TLDR
More evidence-based research and chemical optimization of these compounds could further enhance the effectiveness of these plant-based medicines in angiotherapy.
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This article is published in Trends in Pharmacological Sciences.The article was published on 2006-06-01. It has received 233 citations till now.

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Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

TL;DR: In this paper, the authors discuss how nutraceuticals, such as allicin, apigenin, berberine, butein, caffeic acid, capsaicin, catechin gallate, celastrol, curcumin, epigallocatechin gallates, fisetin, flavopiridol, gambogic acid and genistein, plumbagin, quercetin quercETin, resveratrol, sanguinarine, silibinin, sulforaphane, tax
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Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy

TL;DR: ROS act as a double-edged sword, similar to tumor necrosis factor-α, inflammation, and NF-κB, which provides a great challenge for researchers whose aim is to exploit ROS stress for the development of cancer therapies.
Book ChapterDOI

Ginsenosides: Chemistry, biosynthesis, analysis and potential health effects

TL;DR: Analytical techniques for the analysis of ginsenosides that are described in this chapter are thin-layer chromatography, high-performance liquid chromatography combined with various detectors, gas chromatography), colorimetry, enzyme immunoassays (EIA), capillary electrophoresis (CE), nuclear magnetic resonance (NMR) spectroscopy, and spectrophotometric methods.
Journal ArticleDOI

Ginseng Compounds: An Update on Their Molecular Mechanisms and Medical Applications

TL;DR: The general purpose of this update is to provide information of recently described effects of ginsenosides on antioxidation, vascular system, signal transduction pathways and interaction with receptors.
Journal ArticleDOI

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease.

TL;DR: The mechanism of efficiency of Radix Curcumae formula for the prevention of CCVD is explained, and the potential targets of the Chinese medicines are predicted, which facilitates to elucidate the compatible mechanism of the complex prescription, i.e., "jun-chen-zuo-shi".
References
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Journal ArticleDOI

Tumor Angiogenesis: Therapeutic Implications

TL;DR: This new capillary growth is even more vigorous and continuous than a similar outgrowth of capillary sprouts observed in 2016 and is likely to be accompanied by neovascularization.
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The druggable genome

TL;DR: An assessment of the number of molecular targets that represent an opportunity for therapeutic intervention is crucial to the development of post-genomic research strategies within the pharmaceutical industry.
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Angiogenesis as a therapeutic target

TL;DR: Therapeutic angiogenesis (promoting new vessel growth to treat ischaemic disorders) is an exciting frontier of cardiovascular medicine, but further understanding of the mechanisms of vascular morphogenesis is needed first.