Antimicrobial properties of N-carboxybutyl chitosan.
Riccardo A.A. Muzzarelli,R. Tarsi,O Filippini,Eleonora Giovanetti,G Biagini,Pietro E. Varaldo +5 more
TLDR
Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations, which are of importance in defining the suitability of N- carboxy butyl ch itosan as a wound dressing.Abstract:
N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.read more
Citations
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Journal ArticleDOI
Chitosan as Antimicrobial Agent: Applications and Mode of Action
TL;DR: The current review of 129 references describes the biological activity of several chitosan derivatives and the modes of action that have been postulated in the literature.
Journal ArticleDOI
Chitosan chemistry and pharmaceutical perspectives.
TL;DR: Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. S. Nagar, Punjab-160 062, India, Institute of Biochemistry, Faculty of Medicine, Polytechnic University, Via Ranieri 67, IT-60100 Ancona, Italy, and Department of Medicinal Chemistry & Natural Products,The Hebrew University of Jerusalem, School of Pharmacy-Faculty of medicine, Jerusalem 91120, Israel.
Journal ArticleDOI
Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications
Islem Younes,Marguerite Rinaudo +1 more
TL;DR: Several selected pharmaceutical and biomedical applications are presented, in which chitin and chitosan are recognized as new biomaterials taking advantage of their biocompatibility and biodegradability.
Journal ArticleDOI
Preparation and antibacterial activity of chitosan nanoparticles.
TL;DR: Results show that chitosan nanoparticles and copper-loaded nanoparticles could inhibit the growth of various bacteria tested and exposed to S. choleraesuis led to the disruption of cell membranes and the leakage of cytoplasm.
Journal ArticleDOI
A review of the biomaterials technologies for infection-resistant surfaces.
TL;DR: Among the new strategies, the use of phages or of antisense peptide nucleic acids are discussed, as well as the possibility to modulate the local immune response by active cytokines, to contrast the establishment of an implant infection.
References
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Book ChapterDOI
Chitosan and Other Polyamines: Antifungal Activity and Interaction with Biological Membranes
J. L. Leuba,P. Stossel +1 more
TL;DR: The antifungal effect of chitin was indirect, via antagonistic soil microorganisms, and suppressed total fungal population and stimulated lytic and antibiotic-producing microorganisms such as actinomycetes.
Journal ArticleDOI
Chitosan-Alginate Complex Coacervate Capsules: Effects of Calcium Chloride, Plasticizers, and Polyelectrolytes on Mechanical Stability
Mary M. Daly,Dietrich Knorr +1 more
TL;DR: In this article, a capsule is formed by dropwise addition of a 3% chitosan (polycation) solution into a 0.75% alignate (polyanion) solution.
Book ChapterDOI
Biomedical applications of chitin and chitosan
G. Graham Allan,L.C. Altman,R.E. Bensinger,Debidas Ghosh,Y. Hirabayashi,A. N. Neogi,S. Neogi +6 more
TL;DR: A strategy for the commercialization of chitin and chitosan is outlined starting from the concept that the development of low- volume, high-value speciality applications should precede the creation of high-volume, low-value commodity markets.
Journal ArticleDOI
Formation of spherical chitosan biocatalysts by ionotropic gelation
K.-D. Vorlop,J. Klein +1 more
TL;DR: A new immobilization method is described using the ionotropic gelation of a polycation (chitosan) with different multivalent anionic counterions to immobilize E-coli cells with tryptophan synthetase.
Journal Article
Effects of oxidized cellulose and microfibrillar collagen on infection.
TL;DR: The present study suggests an advantage of oxidized cellulose as compared with microfibrillar collagen from the standpoint of infection, in which a subcutaneous wound model was used.