Journal ArticleDOI
B-type natriuretic peptide (BNP), not ANP, is the principal cardiac natriuretic peptide in vertebrates as revealed by comparative studies.
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TLDR
Comparison studies have revealed that BNP is the only cardiac NP that exists in all tetrapods and teleosts, and it appears that B NP plays pivotal roles in the cardiovascular and body fluid regulation as shown in mammals.About:
This article is published in General and Comparative Endocrinology.The article was published on 2011-05-01. It has received 50 citations till now.read more
Citations
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Journal ArticleDOI
Evolution and development of the building plan of the vertebrate heart.
TL;DR: It is concluded that most features of the high-performance hearts of mammals and birds can be traced back to less developed traits in the hearts of ectothermic vertebrates.
Journal ArticleDOI
Identifying the Evolutionary Building Blocks of the Cardiac Conduction System
Bjarke Jensen,Bjarke Jensen,Bastiaan J. Boukens,Alex V. Postma,Quinn D. Gunst,Maurice J.B. van den Hoff,Antoon F.M. Moorman,Tobias Wang,Vincent M. Christoffels +8 more
TL;DR: This study uncovers the evolutionary building plan of heart and indicates that the building blocks of the conduction system of adult ectothermic vertebrates and embryos of endotherms are similar.
Journal ArticleDOI
Structure and function of the Nppa-Nppb cluster locus during heart development and disease.
TL;DR: Recent insights are provided into the dynamic and complex regulation of Nppa and Nppb during heart development and hypertrophy, and the association of this gene cluster with the cardiomyocyte-intrinsic program of heart regeneration.
Journal ArticleDOI
Human and equine cardiovascular endocrinology: beware to compare
Nicky Van Der Vekens,Ingrid Hunter,Jens P. Goetze,Annelies Decloedt,Dominique De Clercq,Gunther van Loon +5 more
TL;DR: Comparison between human and equine cardiac biomarker studies show important species differences, which can partly be explained by variations in physiology or pathophysiology.
Journal ArticleDOI
Impact of age, phenotype and cardio‐renal function on plasma C‐type and B‐type natriuretic peptide forms in an adult population
Timothy C. R. Prickett,Robert C. Olney,Vicky A. Cameron,M. J. Ellis,Arthur Mark Richards,Eric A. Espiner +5 more
TL;DR: Variations in plasma concentrations of C‐type natriuretic peptide in healthy adults inhealthy adults are ill‐defined, limiting their clinical application.
References
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Journal ArticleDOI
The stress response in fish
TL;DR: Although the species studied comprise a small and nonrepresentative sample of the almost 20,000 known teleost species, there are many indications that the stress response is variable and flexible in fish, in line with the great diversity of adaptations that enable these animals to live in a large variety of aquatic habitats.
Journal ArticleDOI
A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats
A. J. De Bold,A. J. De Bold,H.B. Borenstein,H.B. Borenstein,A. T. Veress,A. T. Veress,H. Sonnenberg,H. Sonnenberg +7 more
TL;DR: It is concluded that the atrial extract contained an extremely powerful inhibitor of renal tubular NaCl re absorption, which caused a rapid, more than 30-fold increase of sodium and chloride excretions, while urine volume and potassium excretion doubled.
Journal ArticleDOI
A new natriuretic peptide in porcine brain
TL;DR: The brain natriuretic peptide (BNP) as mentioned in this paper was identified in porcine brain of a novel peptide of 26 amino acid residues, eliciting a pharmacological spectrum very similar to that of ANP.
Journal ArticleDOI
Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide.
Masashi Mukoyama,Kazumasa Nakao,Kiminori Hosoda,Shin Ichi Suga,Yoshihiko Saito,Yoshihiro Ogawa,Gotaro Shirakami,Michihisa Jougasaki,K Obata,Hirofumi Yasue +9 more
TL;DR: Results indicate that BNP is a novel cardiac hormone secreted predominantly from the ventricle, and that the synthesis, secretion and clearance of BNP differ from those of ANP, suggesting discrete physiological and pathophysiological roles of HBNP in a dual natriuretic peptide system.
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Purification and complete amino acid sequence of α-human atrial natriuretic polypeptide (α-hANP)
Kenji Kangawa,Hisayuki Matsuo +1 more
TL;DR: A survey for natriuretic factors in human atrial extract was performed by using in vitro assay for the relaxant effect on the contractility of chick rectum.
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