Journal ArticleDOI
Bioavailability enhancement of curcumin by complexation with phosphatidyl choline.
Nishant Gupta,Vinod Kumar Dixit +1 more
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The results of ex vivo study show that CU-PC complex has significantly increased absorption compared with curcumin, when given in equimolar doses, and enhanced bioavailability and improved pharmacokinetics.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 2011-05-01. It has received 106 citations till now. The article focuses on the topics: Curcumin & Bioavailability.read more
Citations
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Journal ArticleDOI
Curcumin—From Molecule to Biological Function
TL;DR: This Review describes the development of curcumin from a "traditional" spice and food coloring to a "modern" biological regulator.
Journal ArticleDOI
Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment
TL;DR: This review mainly focuses on the anti-inflammatory potential of curcumin and recent developments in dosage form and nanoparticulate delivery systems with the possibilities of therapeutic application ofCurcumin for the prevention and/or treatment of cancer.
Journal ArticleDOI
The Molecular Basis for the Pharmacokinetics and Pharmacodynamics of Curcumin and Its Metabolites in Relation to Cancer
TL;DR: This review addresses the oncopharmacological properties of curcumin at the molecular level, whereby the phenotypical/biological changes induced in cancer cells upon completion of theCurcumin-triggered signaling cascade(s) are addressed in the framework of the hallmarks of cancer.
Journal ArticleDOI
Oral bioavailability of curcumin: problems and advancements
TL;DR: Recent studies in the design and development of oral delivery systems for curcumin to enhance the solubility and oral bioavailability, including liposomes, nanoparticles and polymeric micelles, phospholipid complexes, and microemulsions are summarized.
Journal ArticleDOI
Epigenetic diet: impact on the epigenome and cancer
TL;DR: Dietary factors that have been demonstrated to influence the epigenome and that may be used in conjunction with other cancer prevention and chemotherapeutic therapies are focused on.
References
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Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
Book ChapterDOI
Preparation of isolated rat liver cells.
TL;DR: This chapter discusses preparation of isolated rat liver cells by incubation of rat liver minces with pronase, which results in most of the liver parenchyma is digested, while nonparenchymal cells remain intact and can be recovered from the incubate.
Journal ArticleDOI
Bioavailability of curcumin: problems and promises.
TL;DR: Enhanced bioavailability of curcumin in the near future is likely to bring this promising natural product to the forefront of therapeutic agents for treatment of human disease.
Journal Article
Anticancer potential of curcumin: preclinical and clinical studies.
TL;DR: Evidence has also been presented to suggest that curcumin can suppress tumor initiation, promotion and metastasis, and Pharmacologically,Curcumin has been found to be safe.
Journal ArticleDOI
Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers
TL;DR: The study shows that in the dosages used, piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.