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Open AccessJournal ArticleDOI

Biocompatible and biodegradable nanoparticles for enhancement of anti-cancer activities of phytochemicals.

TLDR
Nanotechnology opens a door for developing phytochemical-loaded nanoparticles for prevention and treatment of cancer.
About
This article is published in Chinese Journal of Natural Medicines.The article was published on 2015-09-01 and is currently open access. It has received 91 citations till now. The article focuses on the topics: Solid lipid nanoparticle & Drug carrier.

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Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges

TL;DR: The origin and structure of exosomes as well as their biological functions are outlined and specific applications of exOSomes as drug delivery systems in pharmaceutical drug development are focused on.
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Exosomes: new molecular targets of diseases

TL;DR: This review focuses on the functional use of exosomes in therapy and the potential advantages and challenges in using exosome for therapeutic purposes.
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Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases.

TL;DR: An updated review of this fast-progressing field of EVs and their role in brain diseases, particularly focusing in their therapeutic applications, and recently-emerged promising derivations are discussed.
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Green synthesis, characterization and catalytic degradation studies of gold nanoparticles against congo red and methyl orange.

TL;DR: Novel and greener method for synthesis of gold nanoparticles (AuNPs) using 5,7-dihydroxy-6-metoxy-3',4'methylenedioxyisoflavone (Dalspinin), isolated from the roots of Dalbergia coromandeliana was carried out for the first time.
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Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E

TL;DR: Resveratrol-loaded solid lipid nanoparticles functionalized with apolipoprotein E which can be recognized by the LDL receptors overexpressed on the blood–brain barrier were functionalized to protect it from degradation in the blood stream.
References
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Cancer statistics, 2016

TL;DR: Overall cancer incidence trends are stable in women, but declining by 3.1% per year in men, much of which is because of recent rapid declines in prostate cancer diagnoses, and brain cancer has surpassed leukemia as the leading cause of cancer death among children and adolescents.
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Cancer statistics, 2015.

TL;DR: The overall cancer death rate decreased from 215.1 (per 100,000 population) in 1991 to 168.7 in 2011, a total relative decline of 22%.
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Recent advances with liposomes as pharmaceutical carriers.

TL;DR: For further successful development of this field, promising trends must be identified and exploited, albeit with a clear understanding of the limitations of these approaches.
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Bioavailability of curcumin: problems and promises.

TL;DR: Enhanced bioavailability of curcumin in the near future is likely to bring this promising natural product to the forefront of therapeutic agents for treatment of human disease.
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Drug Delivery Systems: Entering the Mainstream

TL;DR: There is considerable interest in exploiting the advantages of DDS for in vivo delivery of new drugs derived from proteomics or genomics research and for their use in ligand-targeted therapeutics.
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