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Open AccessJournal ArticleDOI

Biological activities of Curcuma longa L.

TLDR
An overview of the pharmacological activities of C. longa L., showing its importance, and experiments showing the anti-parasitic, anti-inflammatory potency of curcumin and extracts of this plant by parenteral and oral application in animal models.
Abstract
There are several data in the literature indicating a great variety of pharmacological activities of Curcuma longa L. (Zingiberaceae), which exhibit anti-inflammatory, anti-human immunodeficiency virus, anti-bacteria, antioxidant effects and nematocidal activities. Curcumin is a major component in Curcuma longa L., being responsible for its biological actions. Other extracts of this plant has been showing potency too. In vitro, curcumin exhibits anti-parasitic, antispasmodic, anti-inflammatory and gastrointestinal effects; and also inhibits carcinogenesis and cancer growth. In vivo, there are experiments showing the anti-parasitic, anti-inflammatory potency of curcumin and extracts of C. longa L. by parenteral and oral application in animal models. In this present work we make an overview of the pharmacological activities of C. longa L., showing its importance.

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Journal ArticleDOI

Curcumin as “Curecumin”: From kitchen to clinic

TL;DR: Curcumin, a spice once relegated to the kitchen shelf, has moved into the clinic and may prove to be "Curecumin", a therapeutic agent in wound healing, diabetes, Alzheimer disease, Parkinson disease, cardiovascular disease, pulmonary disease, and arthritis.
Book ChapterDOI

Curcumin: The Indian solid gold

TL;DR: Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities and thus has a potential against various malignant diseases, diabetes, allergies, arthritis, Alzheimer's disease, and other chronic illnesses.
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Turmeric and curcumin: Biological actions and medicinal applications

TL;DR: Safety evaluation studies indicate that both turmeric and curcumin are well tolerated at a very high dose without any toxic effects, and have the potential for the development of modern medicine for the treatment of various diseases.
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A review on antibacterial, antiviral, and antifungal activity of curcumin.

TL;DR: Previous antimicrobial studies of curcumin are summarized towards its application in the future studies as a natural antimicrobial agent.
Journal ArticleDOI

Biological Properties of Curcumin-Cellular and Molecular Mechanisms of Action

TL;DR: The most detailed studies using curcumin include anti-inflammatory, antioxidant, anticarcinogenic, antiviral, and antiinfectious activities as discussed by the authors, and wound healing and detoxifying properties have also received considerable attention.
References
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Journal ArticleDOI

Pharmacology of Curcuma longa

TL;DR: It appears that when given orally, curcumin is far less active than after i.p. administration, and systemic effects seem to be questionable after oral application except that they occur at very low concentrations ofCurcumin, which does not exclude a local action in the gastrointestinal tract.
Journal ArticleDOI

Review on some plants of Indian traditional medicine with antioxidant activity.

TL;DR: Seven plants contain antioxidant principles, that can explain and justify their use in traditional medicine in the past as well as the present, and are viewed for their historical, etymological, morphological, phytochemical and pharmacological aspects.
Journal Article

Inhibitory Effect of Curcumin, Chlorogenic Acid, Caffeic Acid, and Ferulic Acid on Tumor Promotion in Mouse Skin by 12-O-Tetradecanoylphorbol-13-acetate

TL;DR: The effects of topically applied curcumin, chlorogenic acid, caffeic acid, or ferulic acid on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced epidermal ornithine decarboxylase activity, epidersmal DNA synthesis, and the promotion of skin tumors were evaluated in female CD-1 mice.
Journal ArticleDOI

Pharmacology of diferuloyl methane (curcumin), a non‐steroidal anti‐inflammatory agent*

TL;DR: Some pharmacological actions of curcumin (diferuloyl methane) have been examined in rats, mice and cats and it prevents the inflammation induced increase in SGOT and SGPT levels.
Journal Article

Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.

TL;DR: The inhibitory effects of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on TPA-induced tumor promotion in mouse epidermis parallel their inhibitory effect on T PA-induced epidermal inflammation and epider mal lipoxygenase and cyclo oxygengenase activities.
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