Biomedical Applications of Supramolecular Systems Based on Host-Guest Interactions.
Xing Ma,Yanli Zhao +1 more
TLDR
Host−Guest Supramolecular Chemistry A 1.1.1: Aims to explore the role of “ghostly” particles in the determination of chiral stationary phases and their role in the “spatially modified” states.Abstract:
1. Host−Guest Supramolecular Chemistry A 1.read more
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Supramolecular Amphiphiles Based on Host-Guest Molecular Recognition Motifs.
Journal ArticleDOI
Supramolecular photosensitizers rejuvenate photodynamic therapy.
TL;DR: Recent progress made in the development of supramolecular PSs for rejuvenating PDT will be presented and a view of future advances that will likely be made in this area and their potential clinical applications are provided.
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Supramolecular Polymers in Aqueous Media
TL;DR: This review discusses one-dimensional supramolecular polymers that form in aqueous media and focuses on recent studies that address key challenges in the field, providing mechanistic understanding, rational polymer design, important functionality, robustness, or unusual thermodynamic and kinetic properties.
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Smart Nanoparticles for Drug Delivery Application: Development of Versatile Nanocarrier Platforms in Biotechnology and Nanomedicine
TL;DR: Recent advances of smart nanocarriers composed of organic and inorganic materials offering a wide range of functional nanoplatforms for smart application in biotechnology and nanomedicine are highlighted.
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Surveying macrocyclic chemistry: from flexible crown ethers to rigid cyclophanes
TL;DR: This Review surveys the recent developments of the chemistry of naturally occurring cyclodextrins, along with a variety of synthetic flexible and rigid macrocycles that have drawn their inspiration from Pedersen's ground-breaking discovery of crown ethers in the mid-1960s.
References
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Journal ArticleDOI
Photodynamic therapy of cancer: An update†‡
Patrizia Agostinis,Kristian Berg,Keith A. Cengel,Thomas H. Foster,Albert W. Girotti,Sandra O. Gollnick,Stephen M. Hahn,Michael R. Hamblin,Michael R. Hamblin,Asta Juzeniene,David Kessel,Mladen Korbelik,Johan Emelian Moan,Johan Emelian Moan,Pawel Mroz,Dominika Nowis,Jacques Piette,Brian C. Wilson,Jakub Golab,Jakub Golab +19 more
TL;DR: The photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic procedure that can exert a selective cytotoxic activity toward malignant cells as discussed by the authors, which can prolong survival in patients with inoperable cancers and significantly improve quality of life.
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A species of small antisense RNA in posttranscriptional gene silencing in plants.
TL;DR: The 25-nucleotide antisense RNA detected in transgene-induced PTGS is likely synthesized from an RNA template and may represent the specificity determinant of PTGS.
PatentDOI
Self-assembly and mineralization of peptide-amphiphile nanofibers
TL;DR: In this paper, pH-induced self-assembly of a peptide-amphiphile was used to make a nanostructured fibrous scaffold reminiscent of extracellular matrix.
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Supramolecular Chemistry—Scope and Perspectives Molecules, Supermolecules, and Molecular Devices (Nobel Lecture)
TL;DR: Developments in molecular and supramolecular design and engineering open perspectives towards the realization of molecular photonic, electronic, and ionic devices that would perform highly selective recognition, reaction, and transfer operations for signal and information processing at the molecular level.
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Drug-like properties and the causes of poor solubility and poor permeability
TL;DR: There are currently about 10000 drug-like compounds, and true diversity does not exist in experimental combinatorial chemistry screening libraries because current ADME experimental screens are multi-mechanisms, and predictions get worse as more data accumulates.