Journal ArticleDOI
Breast cancer screening with tomosynthesis--initial experiences.
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TLDR
The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study.Abstract:
Experiences gained so far using tomosynthesis for breast cancer screening will be reported. A short summary of results from preparatory studies will also be presented. The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study. Over 2000 women have been examined so far with BT and DM. The BT reading is significantly more time-consuming than the DM reading. Preparatory studies have shown that BT has a higher diagnostic precision and higher accuracy of size measurements and stage determination than DM. There is potential to use lower compression force with BT compared with DM, without decreasing the diagnostic accuracy. BT might play an important role in clinical as well as screening mammography. A large-scale population-based study to investigate BT as a screening modality is underway.read more
Citations
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Journal ArticleDOI
Integration of 3D digital mammography with tomosynthesis for population breast-cancer screening (STORM): a prospective comparison study.
Stefano Ciatto,Nehmat Houssami,Daniela Bernardi,Francesca Caumo,Marco Pellegrini,Silvia Brunelli,Paola Tuttobene,Paola Bricolo,Carmine Fantò,Marvi Valentini,Stefania Montemezzi,Petra Macaskill +11 more
TL;DR: Integrated 2D and 3D mammography improves breast-cancer detection and has the potential to reduce false positive recalls.
Journal ArticleDOI
Digital Breast Tomosynthesis: State of the Art.
TL;DR: The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening.
Journal ArticleDOI
Overview of the evidence on digital breast tomosynthesis in breast cancer detection.
Nehmat Houssami,Per Skaane +1 more
TL;DR: Preliminary data from population screening trials suggest that the integration of DBT with conventional DM may substantially improve breast cancer detection, although final results are not yet available, and many logistical issues need further evaluation to determine the potential implications and cost of combined 2D + 3D mammographic screening.
Journal ArticleDOI
The TOMMY trial: a comparison of TOMosynthesis with digital MammographY in the UK NHS Breast Screening Programme - a multicentre retrospective reading study comparing the diagnostic performance of digital breast tomosynthesis and digital mammography with digital mammography alone.
Fiona J. Gilbert,Lorraine Tucker,Maureen G. C. Gillan,Paula Willsher,Julie Cooke,Karen A Duncan,Michael J Michell,Hilary M Dobson,Yit Yoong Lim,Hema Purushothaman,Celia Strudley,Susan M. Astley,Oliver Morrish,Kenneth C. Young,Stephen W. Duffy +14 more
TL;DR: The specificity of DBT and 2D was better than 2D alone but there was only marginal improvement in sensitivity, and the performance of synthetic 2D appeared to be comparable to standard 2D.
Journal ArticleDOI
Breast screening using 2D-mammography or integrating digital breast tomosynthesis (3D-mammography) for single-reading or double-reading--evidence to guide future screening strategies
Nehmat Houssami,Petra Macaskill,Daniela Bernardi,Francesca Caumo,Marco Pellegrini,Silvia Brunelli,Paola Tuttobene,Paola Bricolo,Carmine Fantò,Marvi Valentini,Stefano Ciatto +10 more
TL;DR: Estimated FP:TP ratios showed that 2D/3D-mammography screening strategies had more favourable FP to TP trade-off and higher sensitivity, applying single-reading or double-reading, relative to 2D-northern Italy population-based screening services.
References
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BookDOI
European guidelines for quality assurance in breast cancer screening and diagnosis
I Amendoeira,Nicholas Perry,Mireille J. M. Broeders,C de Wolf,Sven Törnberg,Robert Holland,L. von Karsa +6 more
TL;DR: The present supplements to the fourth edition of the European guidelines for quality assurance in breast cancer screening and diagnosis lay a cornerstone for a new, completely revised fifth editions of the guidelines.
Journal ArticleDOI
Digital tomosynthesis in breast imaging.
Loren T. Niklason,B T Christian,L E Niklason,Daniel B. Kopans,D E Castleberry,Beale Opsahl-Ong,C E Landberg,Priscilla J. Slanetz,Angela A. Giardino,Richard D. Moore,D Albagli,M C DeJule,Paul Fitzgerald,D F Fobare,B W Giambattista,R F Kwasnick,J Liu,S J Lubowski,G E Possin,J F Richotte,C Y Wei,R F Wirth +21 more
TL;DR: Tomosynthesis may improve the specificity of mammography with improved lesion margin visibility and may improve early breast cancer detection, especially in women with radiographically dense breasts.
Journal ArticleDOI
Digital breast tomosynthesis: initial experience in 98 women with abnormal digital screening mammography.
TL;DR: In this article, the authors compared the image quality of tomosynthesis with that of conventional mammography and estimated the recall rate of screening when Tomosynthesis is used in addition to mammography.
Journal ArticleDOI
Tomographic mammography using a limited number of low-dose cone-beam projection images
Tao Wu,Alex Stewart,Martin Stanton,Thomas G. McCauley,Walter Charles Phillips,Daniel B. Kopans,Richard H. Moore,Jeffrey Wayne Eberhard,Beale Opsahl-Ong,Loren T. Niklason,Mark B. Williams +10 more
TL;DR: A method is described for using a limited number of low-dose radiographs to reconstruct the three-dimensional distribution of x-rays attenuation in the breast, using x-ray cone-beam imaging, an electronic digital detector, and constrained nonlinear iterative computational techniques.