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Journal ArticleDOI

Cardiovascular Comorbidity in COPD: Systematic Literature Review

TLDR
Available observational data support the hypothesis that COPD is associated with an increased risk of CVD, and two studies found a relationship between the severity of airflow limitation and CVD risk.
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This article is published in Chest.The article was published on 2013-10-01. It has received 251 citations till now. The article focuses on the topics: Rate ratio & COPD.

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Citations
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Journal ArticleDOI

Coronary heart disease and heart failure in asthma, COPD and asthma-COPD overlap.

TL;DR: Risks of coronary heart disease and heart failure were increased in asthma, COPD and ACO and it is suggested that cardiovascular risk factors should be assessed systematically in individuals with obstructive airway disease with the potential to facilitate targeted treatments.
Journal ArticleDOI

Subclinical atherosclerosis risk markers in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.

TL;DR: Findings indicate that COPD, even in mild to moderate patients, had greater impaired markers of subclinical atherosclerosis and cardiovascular risk, and Meta-regression analysis revealed that spirometry (as expressed by FEV1%predicted) might influence on PWV.
Journal ArticleDOI

Shared mechanisms of multimorbidity in COPD, atherosclerosis and type-2 diabetes: the neutrophil as a potential inflammatory target.

TL;DR: This review explores the current scientific evidence for inflammation, cellular ageing and cellular processes, such as reactive oxygen species production and phenotypic changes in the pathogenesis of COPD, T2D and atherosclerosis; highlighting common mechanisms shared across these diseases.
Journal ArticleDOI

Association between chronic obstructive pulmonary disease and serum lipid levels: a meta-analysis

TL;DR: Excluding the impact of hypolipidemic treatment on serum lipid profile, TG levels were higher in patients with COPD than in healthy individuals, suggesting that physicians should screen COPD patients for elevated TG levels to reduce the risk of cardiovascular morbidity and mortality.
Journal ArticleDOI

Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan.

TL;DR: The prevalence of airflow limitation in this study indicates that a quarter of outpatients with CVD have COPD, almost all of whom are undiagnosed, which suggests that it is important to look routinely for COPD in CVD outpat patients.
References
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Journal ArticleDOI

Association between chronic obstructive pulmonary disease and systemic inflammation: a systematic review and a meta-analysis

TL;DR: Reduced lung function is associated with increased levels of systemic inflammatory markers which may have important pathophysiological and therapeutic implications for subjects with stable COPD.
Journal ArticleDOI

Prevalence and outcomes of diabetes, hypertension and cardiovascular disease in COPD.

TL;DR: Subjects with GOLD stage 3 or 4 COPD had a higher prevalence of diabetes, which contributes to a higher risk of adverse outcomes of mortality and hospitalisations, and subjects with impaired lung function had more comorbid disease.
Journal ArticleDOI

Mortality in COPD: Role of comorbidities.

TL;DR: The current paper reviews the role of comorbidities in chronic obstructive pulmonary disease mortality, the putative underlying pathogenic link between chronic obstructives pulmonary disease and comorbrid conditions (i.e. inflammation), and the tools used to predict Chronic obstructivemonary disease mortality.
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Systemic effects of chronic obstructive pulmonary disease

TL;DR: In this article, the authors discuss the following systemic effects of chronic obstructive pulmonary disease: 1) systemic inflammation; 2) nutritional abnormalities and weight loss; 3) skeletal muscle dysfunction; 4) other potential systemic effects.
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