Carvedilol for Prevention of Chemotherapy-Related Cardiotoxicity: The CECCY Trial.
Mônica Samuel Avila,Silvia Moreira Ayub-Ferreira,Mauro Rogerio de Barros Wanderley Jr.,Fátima das Dores Cruz,Sara Michelly Gonçalves Brandão,Vagner Oliveira Carvalho Rigaud,Marilia Harumi Higuchi-dos-Santos,Ludhmila Abrahão Hajjar,Roberto Kalil Filho,Paulo M. Hoff,Marina Sahade,Marcela S. M. Ferrari,Romulo Leopoldo de Paula Costa,Max S. Mano,Cecilia Cruz,Maria Cristina Donadio Abduch,Marco Stephan Lofrano Alves,Guilherme Veiga Guimarães,Victor Sarli Issa,Márcio Sommer Bittencourt,Edimar Alcides Bocchi +20 more
TLDR
In this largest clinical trial of β-blockers for prevention of cardiotoxicity under contemporary ANT dosage, the use of carvedilol resulted in a significant reduction in troponin levels and diastolic dysfunction.Citations
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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Paul A. Heidenreich,Biykem Bozkurt,David Aguilar,Larry A. Allen,Joni J. Byun,Monica Colvin,Anita Deswal,Mark H. Drazner,Shannon M. Dunlay,Linda R. Evers,James C. Fang,Savitri Fedson,Gregg C. Fonarow,Salim S. Hayek,Adrian F. Hernandez,Prateeti Khazanie,Michelle M. Kittleson,Christopher S. Lee,Mark S. Link,Carmelo A. Milano,Lorraine C. Nnacheta,Alexander T. Sandhu,Lynne W. Stevenson,Orly Vardeny,Amanda R. Vest,Clyde W. Yancy +25 more
TL;DR: The "2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure" as discussed by the authors provides patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure.
Journal ArticleDOI
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
TL;DR: The 2022 guideline as discussed by the authors provides patient-centric recommendations for clinicians to prevent, diagnose, and manage patients with heart failure, with the intent to improve quality of care and align with patients' interests.
Journal ArticleDOI
Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations
Giuseppe Curigliano,Daniel J. Lenihan,Michael G. Fradley,Sarju Ganatra,Ana Barac,Anne H. Blaes,Jörg Herrmann,Charles B. Porter,Alexander R. Lyon,Patrizio Lancellotti,Aarti Patel,Jeanne M. DeCara,Joshua D. Mitchell,Eric E. Harrison,Javid Moslehi,Ronald M. Witteles,Maria Grazia Calabrò,Roberto Orecchia,E. de Azambuja,J. L. Zamorano,Ron Krone,Zaza Iakobishvili,Joseph R. Carver,Saro H. Armenian,Bonnie Ky,Daniela Cardinale,Carlo M. Cipolla,Susan Dent,Karin Jordan +28 more
TL;DR: Common CV toxicities related to cancer therapy are defined, along with suggested strategies for prevention, detection and treatment, and guidance regarding prevention, screening, monitoring and treatment of CV toxicity is provided.
Journal ArticleDOI
The updated landscape of tumor microenvironment and drug repurposing.
Ming-Zhu Jin,Weilin Jin +1 more
TL;DR: An updated image of TME with emphasis on hypoxic niche, immune microenvironment, metabolism micro environment, acidic niche, innervated niche, and mechanical microenvironment is presented and conventional drugs including aspirin, celecoxib, β-adrenergic antagonist, metformin, and statin are summarized in new antitumor application.
Journal ArticleDOI
Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: Endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association.
Biykem Bozkurt,Andrew J.S. Coats,Hiroyuki Tsutsui,Ca Magdy Abdelhamid,Stamatis Adamopoulos,Nancy M. Albert,Stefan D. Anker,John Atherton,Michael Böhm,Javed Butler,Mark H. Drazner,G. Michael Felker,Gerasimos Filippatos,Mona Fiuzat,Gregg C. Fonarow,Juan Esteban Gomez-Mesa,Paul A. Heidenreich,Teruhiko Imamura,Ewa A. Jankowska,James L. Januzzi,Prateeti Khazanie,Koichiro Kinugawa,Carolyn S.P. Lam,Yuya Matsue,Marco Metra,Tomohito Ohtani,Massimo F Piepoli,Piotr Ponikowski,Giuseppe M.C. Rosano,Yasushi Sakata,Petar M. Seferović,Randall C. Starling,John R. Teerlink,Orly Vardeny,Kazuhiro Yamamoto,Clyde W. Yancy,Jian Zhang,Shelley Zieroth +37 more
TL;DR: In this paper, a universal definition of heart failure (HF) was proposed, with symptoms and signs caused by structural and functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion.
References
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Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.
Roberto M. Lang,Luigi P. Badano,Victor Mor-Avi,Jonathan Afilalo,Anderson C. Armstrong,Laura Ernande,Frank A. Flachskampf,Elyse Foster,Steven A. Goldstein,Tatiana Kuznetsova,Patrizio Lancellotti,Denisa Muraru,Michael H. Picard,Ernst Rietzschel,Lawrence G. Rudski,Kirk T. Spencer,Wendy Tsang,Jens-Uwe Voigt +17 more
TL;DR: This document provides updated normal values for all four cardiac chambers, including three-dimensional echocardiography and myocardial deformation, when possible, on the basis of considerably larger numbers of normal subjects, compiled from multiple databases.
Journal ArticleDOI
Cancer treatment and survivorship statistics, 2016.
Kimberly D. Miller,Rebecca L. Siegel,Chun Chieh Lin,Angela B. Mariotto,Joan L. Kramer,Julia H. Rowland,Kevin Stein,Rick Alteri,Ahmedin Jemal +8 more
TL;DR: The number of cancer survivors continues to increase because of both advances in early detection and treatment and the aging and growth of the population and for the public health community to better serve these survivors, the American Cancer Society and the National Cancer Institute collaborate to estimate the number of current and future cancer survivors.
Journal ArticleDOI
Recommendations for the evaluation of left ventricular diastolic function by echocardiography
Sherif F. Nagueh,Christopher P. Appleton,Thierry C. Gillebert,Paolo Marino,Jae K. Oh,Otto A. Smiseth,Alan D. Waggoner,Frank A. Flachskampf,Patricia A. Pellikka,Arturo Evangelista +9 more
TL;DR: Recommendations for the evaluation of left ventricular diastolic function by echocardiography are made and further research is needed to determine the best method for this evaluation.
Journal ArticleDOI
Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging
Sherif F. Nagueh,Otto A. Smiseth,Christopher P. Appleton,Benjamin F. Byrd,Hisham Dokainish,Thor Edvardsen,Frank A. Flachskampf,Thierry C. Gillebert,Allan L. Klein,Patrizio Lancellotti,Paolo Marino,Jae K. Oh,Bogdan A. Popescu,Alan D. Waggoner +13 more
TL;DR: Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography and the European Association of Cardiovascular Imaging are presented.
Journal ArticleDOI
2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines
José Luis Zamorano,Patrizio Lancellotti,Daniel Rodriguez Muñoz,Victor Aboyans,Riccardo Asteggiano,Maurizio Galderisi,Gilbert Habib,Daniel J. Lenihan,Gregory Y.H. Lip,Alexander R. Lyon,Teresa López Fernández,Dania Mohty,Massimo F. Piepoli,Juan Tamargo,Adam Torbicki,Thomas M. Suter +15 more
TL;DR: This document describes the development and use of angiotensin-converting enzyme, a non-volatile substance that acts as a “spatially aggregating substance” to reduce the chances of heart attack in women.
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2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines
Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.
Juan Carlos Plana,Maurizio Galderisi,Ana Barac,Michael S. Ewer,Bonnie Ky,Marielle Scherrer-Crosbie,Javier Ganame,Igal A. Sebag,Deborah A. Agler,Luigi P. Badano,Jose Banchs,Daniela Cardinale,Joseph R. Carver,Manuel D. Cerqueira,Jeanne M. DeCara,Thor Edvardsen,Scott D. Flamm,Thomas Force,Brian P. Griffin,Guy Jerusalem,Jennifer E. Liu,Andreia Magalhaes,Thomas H. Marwick,Liza Y. Sanchez,Rosa Sicari,Hector R. Villarraga,Patrizio Lancellotti +26 more