Journal ArticleDOI
Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries.
Gaby Danan,Christian Bénichou +1 more
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In this paper, a new method for drug causality assessment is described and applied to reports of acute liver injuries, using reports with positive rechallenge as external standard.About:
This article is published in Journal of Clinical Epidemiology.The article was published on 1993-11-01. It has received 1291 citations till now. The article focuses on the topics: Adverse drug reaction.read more
Citations
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A prospective study of the incidence of drug-induced liver injury by the modern volatile anaesthetics sevoflurane and desflurane.
Bridget Bishop,Nicholas Hannah,Adam Doyle,Adam Doyle,Francesco Amico,Brad Hockey,David Moore,Siddharth Sood,Siddharth Sood,Alexandra Gorelik,Alexandra Gorelik,Danny Liew,Danny Liew,Danny Liew,Dolores B. Njoku,Amanda Nicoll +15 more
TL;DR: Volatile anaesthetics are known to cause drug‐induced liver injury, a hepatotoxic reaction characterised by antibodies to trifluoroacetylated lipid and protein adducts and cytochrome p450 2E1.
Journal ArticleDOI
Antimitochondrial Rather than Antinuclear Antibodies Correlate with Severe Drug-Induced Liver Injury.
TL;DR: A closer look in a causality proven DILI cohort provided no evidence that presence of ANA titers is specific for DILi by a certain medication.
Journal ArticleDOI
Drug-induced liver injury in Australia, 2009–2020: the increasing proportion of non-paracetamol cases linked with herbal and dietary supplements
Emily Nash,Abdul-Hamid Sabih,John David Chetwood,Georgette Wood,Keval Pandya,Terry Yip,Avik Majumdar,Avik Majumdar,Geoffrey W. McCaughan,Geoffrey W. McCaughan,Simone I. Strasser,Simone I. Strasser,Ken Liu,Ken Liu +13 more
TL;DR: In this article, the authors compared the characteristics and outcomes of drug-induced liver injury (DILI) caused by paracetamol and non-paracetamols medications, particularly herbal and dietary supplements.
Journal ArticleDOI
Methylprednisolone-induced acute liver injury in a patient treated for multiple sclerosis relapse.
TL;DR: An immune rebound phenomenon could be responsible for rare but true hepatotoxicity of high-dose methylprednisolone therapy in patients treated for multiple sclerosis relapse.
Journal ArticleDOI
[Adverse drugs reactions: diagnosis and assessment].
TL;DR: ADR-associated drugs come predominantly from the class of non-steroidal antiinflammatory drugs, anticoagulants, acetylsalicylic acid and cardiovascular drugs and they present as gastrointestinal bleeding and adverse cardiovascular effects.
References
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Journal Article
Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France
Journal ArticleDOI
Causality assessment of adverse reactions to drugs--II. An original model for validation of drug causality assessment methods: case reports with positive rechallenge.
TL;DR: It is concluded that adverse drug reaction reports with a positive rechallenge can provide a standard for validation of causality assessment methods, and RUCAM applied to drug-induced liver injuries has been validated.
Journal ArticleDOI
An Algorithm for the Operational Assessment of Adverse Drug Reactions: I. Background, Description, and Instructions for Use
TL;DR: An algorithm is developed that provides detailed operational criteria for ranking the probability of causation when ADR is suspected between a drug and a clinical manifestation.
Journal ArticleDOI
Toward the operational identification of adverse drug reactions.
Fred E. Karch,Louis Lasagna +1 more
TL;DR: A decision table algorithm approach is presented toward the development of an operational system for the identification of adverse drug reactions that incorporates an estimate of the certainty of the link between the untoward clinical event and the suspect drug, and examines the underlying causes of the identified drug reactions.
Journal ArticleDOI
Assessing methods for causality assessment of suspected adverse drug reactions
Tom A. Hutchinson,David A. Lane +1 more
TL;DR: Six alternative criteria are described that attempt to address a potential user's main concerns--the need to know whether to believe the results in general and in a particular case and focus on the internal structure of a method rather than its output.
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Raúl J. Andrade,M. Isabel Lucena,M. Carmen Fernández,G. Pelaez,Ketevan Pachkoria,Elena García-Ruiz,B. García-Muñoz,Rocío González-Grande,Angeles Pizarro,José Antonio Durán,Manuel Jimenez,Luis Rodrigo,Manuel Romero-Gómez,J.M. Navarro,Ramon Planas,Joan Costa,Africa Borras,Aina Soler,Javier Salmerón,Rafael Martín-Vivaldi +19 more