Journal ArticleDOI
Causality assessment of adverse reactions to drugs--I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries.
Gaby Danan,Christian Bénichou +1 more
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TLDR
In this paper, a new method for drug causality assessment is described and applied to reports of acute liver injuries, using reports with positive rechallenge as external standard.About:
This article is published in Journal of Clinical Epidemiology.The article was published on 1993-11-01. It has received 1291 citations till now. The article focuses on the topics: Adverse drug reaction.read more
Citations
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Journal ArticleDOI
Drug-Induced Liver Injury Network Causality Assessment: Criteria and Experience in the United States
TL;DR: This review will discuss the DILIN expert opinion process, its strengths and weaknesses, psychometric performance and future.
Journal ArticleDOI
Drug induced liver injury: accuracy of diagnosis in published reports.
TL;DR: Alternative diagnoses are common in primarily suspected DILI cases and should be excluded early in future cases, requiring a thorough clinical and causality assessment.
Journal ArticleDOI
Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb Polygonum multiflorum
Jia-bo Wang,Zhi-Jie Ma,Zhi-Jie Ma,Ming Niu,Yun Zhu,Qingsheng Liang,Yan-ling Zhao,Jingyuan Song,Zhao-fang Bai,Yaming Zhang,Ping Zhang,Na Li,Ya-kun Meng,Qi Li,Lu-shan Qin,Guangju Teng,Jun-ling Cao,Bao-Sen Li,Shilin Chen,Yonggang Li,Zheng-sheng Zou,Honghao Zhou,Xiao-He Xiao +22 more
TL;DR: Screening methods for Heshouwu DILI diagnosis addresses safety concerns regarding stilbene-containing herbal medicines and dietary supplements and excludes Toxin (heavy metals, pesticides, and mycotoxins) contamination.
Journal ArticleDOI
Acute liver failure induced by idiosyncratic reaction to drugs: Challenges in diagnosis and therapy
Shannan R. Tujios,William M. Lee +1 more
TL;DR: DILI that reaches the threshold of ALF will more often than not require transplantation, since survival without transplant is around 25%.
Journal ArticleDOI
Herbal hepatotoxicity: a hidden epidemic
TL;DR: The problem of the lacks of standardization of herbal drugs, the lack of randomized clinical trials regarding the majority of these products, the unawareness of risks by the patients who buy and use them, and the problem of underreporting are discussed.
References
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Journal Article
Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France
Journal ArticleDOI
Causality assessment of adverse reactions to drugs--II. An original model for validation of drug causality assessment methods: case reports with positive rechallenge.
TL;DR: It is concluded that adverse drug reaction reports with a positive rechallenge can provide a standard for validation of causality assessment methods, and RUCAM applied to drug-induced liver injuries has been validated.
Journal ArticleDOI
An Algorithm for the Operational Assessment of Adverse Drug Reactions: I. Background, Description, and Instructions for Use
TL;DR: An algorithm is developed that provides detailed operational criteria for ranking the probability of causation when ADR is suspected between a drug and a clinical manifestation.
Journal ArticleDOI
Toward the operational identification of adverse drug reactions.
Fred E. Karch,Louis Lasagna +1 more
TL;DR: A decision table algorithm approach is presented toward the development of an operational system for the identification of adverse drug reactions that incorporates an estimate of the certainty of the link between the untoward clinical event and the suspect drug, and examines the underlying causes of the identified drug reactions.
Journal ArticleDOI
Assessing methods for causality assessment of suspected adverse drug reactions
Tom A. Hutchinson,David A. Lane +1 more
TL;DR: Six alternative criteria are described that attempt to address a potential user's main concerns--the need to know whether to believe the results in general and in a particular case and focus on the internal structure of a method rather than its output.
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