Journal ArticleDOI
Characterization of a novel piscidin-like antimicrobial peptide from Pseudosciaena crocea and its immune response to Cryptocaryon irritans
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TLDR
These results provided the first evidence of piscidins antiparasitic activity against marine fish ectoparasites C. irritants trophonts and indicated that Pc-pis might be an important component of the P. crocea innate immune system againstC.About:
This article is published in Fish & Shellfish Immunology.The article was published on 2013-08-01. It has received 77 citations till now. The article focuses on the topics: Signal peptide & Innate immune system.read more
Citations
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Antimicrobial Peptides from Fish
TL;DR: Some of the unique properties of fish peptides, including their ability to act even in very high salt concentrations, make them good potential targets for development as therapeutic antimicrobials.
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Antimicrobial Peptides as Mediators of Innate Immunity in Teleosts.
TL;DR: The capacity to regulate AMPs expression by exogenous factors may prove useful in modulating AMP expression in fish to prevent disease, particularly in aquaculture settings where crowded conditions and environmental stress pre-dispose these fish to infection.
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Fish antimicrobial peptides (AMP's) as essential and promising molecular therapeutic agents: A review.
Uzma Shabir,Sajad Ali,Aqib Rehman Magray,Bashir A. Ganai,Parveena Firdous,Toyeeba Hassan,Ruqeya Nazir +6 more
TL;DR: This review provides an overview of the structures, functions, and putative mechanisms of major families of fish AMPs and highlighted how fish AMP can be used as a novel therapeutic tool which is the theme of future research in drug development.
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High-Resolution Structures and Orientations of Antimicrobial Peptides Piscidin 1 and Piscidin 3 in Fluid Bilayers Reveal Tilting, Kinking, and Bilayer Immersion
B. Scott Perrin,Ye Tian,Riqiang Fu,Christopher V. Grant,Eduard Y. Chekmenev,William E. Wieczorek,Alexander E. Dao,Robert M. Hayden,Caitlin M. Burzynski,Richard M. Venable,Mukesh Sharma,Stanley J. Opella,Richard W. Pastor,Myriam Cotten +13 more
TL;DR: Structural refinement of 1H–15N dipolar couplings and 15N chemical shifts measured by oriented sample solid-state NMR and all-atom molecular dynamics simulations provide structural and orientational information of high precision and accuracy about these interfacially bound α-helical peptides.
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Transcriptome analysis of the Larimichthys crocea liver in response to Cryptocaryon irritans
Panpan Wang,Jun Wang,Yongquan Su,Yong Mao,Zhang Jianshe,Changwen Wu,Qiaozhen Ke,Kun-Huang Han,Wei-Qiang Zheng,Nen-di Xu +9 more
TL;DR: A gene expression pattern for normal and C. irritans-immunized L. croceas is characterized for the first time and sheds new light on the molecular mechanisms underlying the host-C.
References
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Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
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The role of antimicrobial peptides in animal defenses
TL;DR: It is proposed that cationic antimicrobial peptides, which are induced by LPS and are able to dampen the septic response of animal cells to LPS, have a role in feedback regulation of cytokine responses.
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Peptide antibiotics in mast cells of fish
TL;DR: It is shown that 'piscidins', a previously undiscovered family of peptide antibiotics isolated from fish, reside in mast cells, an immune cell of uncertain function that is present in all vertebrate classes.
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Discovery and characterization of two isoforms of moronecidin, a novel antimicrobial peptide from hybrid striped bass.
Xavier Lauth,Hiroko Shike,Jane C. Burns,Mark Westerman,Vaughn Ostland,James M. Carlberg,Jon C. Van Olst,Victor Nizet,Steven W. Taylor,Chisato Shimizu,Philippe Bulet +10 more
TL;DR: Moronecidin this article is a 22-residue, C-terminally amidated antimicrobial peptide from the skin and gill of hybrid striped bass.
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Purification and characterization of three isoforms of chrysophsin, a novel antimicrobial peptide in the gills of the red sea bream, Chrysophrys major
Noriaki Iijima,Norio Tanimoto,Yohko Emoto,Yohko Morita,Kazumasa Uematsu,Tomoya Murakami,Toshihiro Nakai +6 more
TL;DR: Their broad ranging bactericidal activities, combined with their localization in certain cells and eosinophilic granule cell-like cells in the gills, suggest that chrysophsins play a significant role in the innate defense system of red sea bream gills.