Journal ArticleDOI
Comparative assessment of phytochemical profile, antioxidant capacity and anti-proliferative activity in different varieties of brown rice (Oryza sativa L.)
Yue Gao,Xinbo Guo,Yu Liu,Mingwei Zhang,Ruifen Zhang,Arshad Mehmood Abbasi,Lijun You,Tong Li,Rui Hai Liu +8 more
TLDR
In general, bound fractions of brown rice depicted significant variation levels of phytochemicals, antioxidant and anti-proliferative activities, which could be significant to introduce brown rice as functional foods and to increase awareness about health benefits of whole grain.Abstract:
Consumption of brown rice is associated with reduced risk of chronic diseases, which might be attributed to the presence of unique phytochemicals. This study aimed to evaluate phytochemicals profile, cellular antioxidant and anti-proliferative activities in glutinous and non-glutinous brown rice varieties of indica and japonica subspecies. In general, bound fractions of brown rice depicted significant variation levels of phytochemicals, antioxidant and anti-proliferative activities. Anti-proliferative activity of bound fraction, total antioxidant capacity and cellular antioxidant activity of non-glutinous type were significantly higher than glutinous type (pread more
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Brown Rice Versus White Rice: Nutritional Quality, Potential Health Benefits, Development of Food Products, and Preservation Technologies.
TL;DR: The objective of this work was to review the recent advances in research performed for purposes of evaluation of nutritional value and potential health benefits of the whole BR grain and present economic and environmental benefits for the consumption of whole BR instead of the polished or white rice.
Journal ArticleDOI
Assessment of the Phenolic Profiles, Hypoglycemic Activity, and Molecular Mechanism of Different Highland Barley (Hordeum vulgare L.) Varieties.
TL;DR: Highland barley phenolics could inhibit gluconeogenesis and motivate glycogen synthesis via down-regulating the gene expression of G6Pase, PEPCK, and glycogen synthase kinase 3β (GSK3β), while activating the expression of insulin receptor substrate-1 (IRS-1), phosphatidylinositol 3 kinase (PI3K), serine/threonine kinase
Journal ArticleDOI
Phytochemical profiles of rice and their cellular antioxidant activity against ABAP induced oxidative stress in human hepatocellular carcinoma HepG2 cells.
Ersheng Gong,Chengmei Liu,Bin Li,Wei Zhou,Hongyu Chen,Tong Li,Jianyong Wu,Zicong Zeng,Yuehua Wang,Xu Si,Yuxi Lang,Ye Zhang,Weijia Zhang,Guowen Zhang,Shunjing Luo,Rui Hai Liu +15 more
TL;DR: Black rice had the highest total phenolic content and total flavonoid content in free and bound fractions, followed by red rice, brown rice, and polished rice, which contained much more free phenolic compounds than other rice samples.
Journal ArticleDOI
Whole Grain Brown Rice Extrudate Ameliorates the Symptoms of Diabetes by Activating the IRS1/PI3K/AKT Insulin Pathway in db/db Mice.
TL;DR: Results indicate that BRD exhibits antidiabetic potential by activating the IRS1/PI3K/AKT signaling pathway, further regulating the expression of the FOXO1 gene and p-GSK3 protein and thus inhibiting hepatic gluconeogenesis, increasing hepatic glycogen storage and improving insulin resistance.
References
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Journal ArticleDOI
Antiproliferative potential and DNA scission inhibitory activity of phenolics from whole millet grains
TL;DR: It is demonstrated that millet phenolics may be effective in the prevention of cancer initiation and progression in vitro and may serve as a nutraceutical and functional food ingredient in health promotion and disease risk reduction.
Journal ArticleDOI
A modified methylene blue assay for accurate cell counting
TL;DR: This work intended to explore an adaptation of the methylene blue assay to overcome the existing limitations of the procedure, enabling application to a broader range of cell densities and various cell culture plates and was found to be more efficient, accurate and sensitive.
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Diet and risk of chronic diseases: results from the first 8 years of follow-up in the EPIC-Potsdam study
TL;DR: Overall, a healthy diet was characterized by a high consumption of whole-grain bread, raw vegetables and a low consumption of red meat and possibly butter, which is generally in line with previous findings.
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Dynamic changes in the free and bound phenolic compounds and antioxidant activity of brown rice at different germination stages
Ti Huihui,Ruifen Zhang,Mingwei Zhang,Qing Li,Zhencheng Wei,Yan Zhang,Tang Xiaojun,Yuanyuan Deng,Lei Liu,Ma Yongxuan +9 more
TL;DR: Germinated brown rice is a good source of the phenolics associated with antioxidant effects and the increase of bound phenolics exerts beneficial health effects throughout the digestive tract after absorption and may reduce mutations.
Journal ArticleDOI
Synergistic Effect of Apple Extracts and Quercetin 3-β-d-Glucoside Combination on Antiproliferative Activity in MCF-7 Human Breast Cancer Cells in Vitro
Jun Yang,Rui Hai Liu +1 more
TL;DR: The results suggest that the apple extracts plus Q3G combination possesses a synergistic effect in MCF-7 cell proliferation, which is likely to reduce the risk of cancer through dietary modification.