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CT Radiomics Signature of Tumor and Peritumoral Lung Parenchyma to Predict Nonsmall Cell Lung Cancer Postsurgical Recurrence Risk.

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TLDR
Combination of the tumoral and peritumoral RS with TNM staging system outperformedTNM staging alone in individualized recurrence risk estimation of patients with surgically treated NSCLC.
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This article is published in Academic Radiology.The article was published on 2020-04-01. It has received 59 citations till now. The article focuses on the topics: TNM staging system.

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Predicting cancer outcomes with radiomics and artificial intelligence in radiology.

TL;DR: In this article, the authors discuss the next generation of challenges in clinical decision-making that AI tools can solve using radiology images, such as prognostication of outcome across multiple cancers, prediction of response to various treatment modalities, discrimination of benign treatment confounders from true progression, identification of unusual response patterns and prediction of the mutational and molecular profile of tumours.
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Radiomics as a personalized medicine tool in lung cancer: Separating the hope from the hype.

TL;DR: Radiomics studies in NSCLC suffer from a number of limitations, and identification of limitations can help future studies to expedite biomarker translation.
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CT-based radiomics for prediction of histologic subtype and metastatic disease in primary malignant lung neoplasms.

TL;DR: Several radiomic features significantly associated with distant metastasis, nodal metastases, and histology were discovered in this work, presenting great potential as imaging biomarkers for pathological diagnosis and target therapy decision.
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CT-Imaging Based Analysis of Invasive Lung Adenocarcinoma Presenting as Ground Glass Nodules Using Peri- and Intra-nodular Radiomic Features.

TL;DR: The gross radiomic signature of intra- and peri-nodular regions improved the prediction ability and aided predicting the invasiveness of lung adenocarcinoma appearing as GGN.
References
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Journal ArticleDOI

Global cancer statistics, 2012

TL;DR: A substantial portion of cancer cases and deaths could be prevented by broadly applying effective prevention measures, such as tobacco control, vaccination, and the use of early detection tests.
Journal ArticleDOI

Radiomics: Images Are More than Pictures, They Are Data.

TL;DR: This report describes the process of radiomics, its challenges, and its potential power to facilitate better clinical decision making, particularly in the care of patients with cancer.
BookDOI

Regression Modeling Strategies

TL;DR: Regression models are frequently used to develop diagnostic, prognostic, and health resource utilization models in clinical, health services, outcomes, pharmacoeconomic, and epidemiologic research, and in a multitude of non-health-related areas.
Journal ArticleDOI

Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer

TL;DR: Compared with lobectomy, limited pulmonary resection does not confer improved perioperative morbidity, mortality, or late postoperative pulmonary function and lobectomy still must be considered the surgical procedure of choice for patients with peripheral T1 N0 non-small cell lung cancer.
Journal ArticleDOI

Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

TL;DR: The Clatterbridge Cancer Centre and Liverpool Heart and Chest Hospital, Liverpool; University of Aberdeen, Aberdeen, UK; Center for Medical Imaging, University of Groningen, Groningen; Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands; and Department of Thoracic Surgery, University Hospitals of Leicester NHS Trust, Leicester, UK.
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