Current Insights into Potential Effects of Micro-Nanoplastics on Human Health by in-vitro Tests
Marta Llorca,Marinella Farré +1 more
- Vol. 3
TLDR
In this article, the knowledge of human exposure routes and the recent results on the toxicological effects of micro-and nanoplastics in human health are presented and discussed, and the current limitations and the main gaps in the body of knowledge are summarised.Abstract:
Humans are exposed to micro- and nanoplastics (MNPLs) through inhalation, ingestion and, to a lesser extent, dermal contact. In recent years, new insights indicate the potential of MNPLs to cause damages to human health. Particle toxicity can include oxidative stress, inflammatory lesions, and then increased internalization or translocation through tissues. On the other hand, plastic additives are used in plastic particles, once internalized, can release toxic substances. It is noteworthy that the potential effects of MNPLs encompass a wide range of polymers and chemical additives, showing various physicochemical and toxicological properties, and the size, shape and surface properties are other variables influencing their effects. In spite of the research carried out recently, MNPLs research is in its early stages, and further investigation is required. In this review article, the knowledge of human exposure routes and the recent results on the toxicological effects of MNPLs in human health are presented and discussed. Finally, the current limitations and the main gaps in the body of knowledge are summarised.read more
Citations
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Journal ArticleDOI
Impact of Micro- and Nanoplastics on Mitochondria
TL;DR: The impact of micro- and nanoplastics on mitochondria is discussed and current knowledge in this field is reviewed to reflect growing global environmental threats with potential health risks.
Journal ArticleDOI
The Biological Effects of Polystyrene Nanoplastics on Human Peripheral Blood Lymphocytes
Andrea Cancemi,David R. Kaplan +1 more
TL;DR: In this paper , the authors assessed the cytotoxic and genotoxic potential of polystyrene nanoplastics (PSNPs) at different concentrations (2000μg/mL, 1000μg /mL, and 500μg)/mL by using chromosomal aberration (CA) and cytokinesis-block micronucleus assays (CBMN) on human peripheral lymphocytes.
Journal ArticleDOI
Elimination of microplastics from the aquatic milieu: A dream to achieve.
Anirban Goutam Mukherjee,Uddesh Ramesh Wanjari,Pragya Bradu,Megha Patil,Antara Biswas,Reshma Murali,Kaviyarasi Renu,Abhijit Dey,Balachandar Vellingiri,Ganesan Raja,Mahalaxmi Iyer,Abilash Valsala Gopalakrishnan +11 more
TL;DR: In this article , a review provides in-depth knowledge of how microplastics interact with different toxic organic chemicals, antibiotics, and heavy metals in the aquatic environment and its consequences.
Journal ArticleDOI
Bioanalytical approaches for the detection, characterization, and risk assessment of micro/nanoplastics in agriculture and food systems
Chenxu Yu,Paul Takhistov,Evangelyn C. Alocilja,J. I. Reyes De Corcuera,Margaret W. Frey,Carmen L. Gomes,Y. Mao,Eric S. McLamore,Mengshi Lin,Olga V. Tsyusko,Tzuen-Rong J. Tzeng,Jeong Yeol Yoon,Anhong Zhou +12 more
TL;DR: It is concluded that detecting the presence and understanding the impact of MP/NP throughout the agricultural and food supply chain require the development of novel deployable analytical methods and sensors, the combination of high-precision lab analysis with rapid onsite screening, and a data hub that hosts and curates data for future analysis.
Journal ArticleDOI
Impacts of microplastics on immunity
Wenjie Yang,Nahar Jannatun,Yanqiao Zeng,Ting Chu Ken Liu,Guofang Zhang,Chunying Chen,Yang Li +6 more
TL;DR: There is an urgent need to be aware of the harm of MPs to the human immune system and more studies about immunological assessments, and further elucidate the immunological hazards and risks of humans that exposed to MPs.
References
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