Journal ArticleDOI
Dendrimers in oncology: an expanding horizon.
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This article is published in Chemical Reviews.The article was published on 2009-04-23. It has received 459 citations till now. The article focuses on the topics: Horizon (archaeology).read more
Citations
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Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology.
Kim E. Sapsford,W. Russ Algar,Lorenzo Berti,Kelly Boeneman Gemmill,Brendan J. Casey,Eunkeu Oh,Michael H. Stewart,Igor L. Medintz +7 more
TL;DR: Chemistries that Facilitate Nanotechnology Kim E. Sapsford,† W. Russ Algar, Lorenzo Berti, Kelly Boeneman Gemmill,‡ Brendan J. Casey,† Eunkeu Oh, Michael H. Stewart, and Igor L. Medintz .
Journal ArticleDOI
Dendron-Mediated Self-Assembly, Disassembly, and Self-Organization of Complex Systems
Brad M. Rosen,Christopher J. Wilson,Daniela A. Wilson,Mihai Peterca,Mohammad R. Imam,Virgil Percec +5 more
TL;DR: The structural origin of chirality in different supramolecular structures through combinations of structural analysis methods has been investigated in this article, where the most ideal building blocks would need to display shape persistence in solution and in the solid state, since only this feature provides access to the use of complementary methods of structural analyses.
Journal ArticleDOI
The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy
Tennyson L. Doane,Clemens Burda +1 more
TL;DR: This critical review will present the role of nanoparticles (NPs) in the directions that are vital to the new field of nanomedicine, including imaging and drug delivery, and review recent advances in major NP based biomedical applications.
Journal ArticleDOI
Dendrimer as nanocarrier for drug delivery
TL;DR: The present review highlights the contribution of dendrimers in the field of nanotechnology with intent to aid the researchers in exploring dendrisers inThe field of drug delivery.
Journal ArticleDOI
Nanomaterials: Applications in Cancer Imaging and Therapy
TL;DR: A brief description of cancer pathology and the characteristics that are important for tumor‐targeted NM design are provided, followed by an overview of the different types of NMs explored to date, covering synthetic aspects and approaches explored.
References
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Remington : The Science and Practice of Pharmacy
TL;DR: Remington: The Science and Practice of Pharmacy now includes six months free online access to Facts and Comparisons's DrugfactsPlus, the leading source of drug information and pharmacist tools on the Internet.
Journal ArticleDOI
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine
Otmane Boussif,Frank Lezoualc'h,Maria Antonietta Zanta,Mojgan Mergny,Daniel Scherman,Barbara A. Demeneix,Jean-Paul Behr +6 more
TL;DR: Together, these properties make PEI a promising vector for gene therapy and an outstanding core for the design of more sophisticated devices because its efficiency relies on extensive lysosome buffering that protects DNA from nuclease degradation, and consequent lysOSomal swelling and rupture that provide an escape mechanism for the PEI/DNA particles.
Journal ArticleDOI
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review.
TL;DR: The basic characteristics of the EPR effect, particularly the factors involved, are described, as well as its modulation for improving delivery of macromolecular drugs to the tumor.
Journal ArticleDOI
Block copolymer micelles for drug delivery: design, characterization and biological significance
TL;DR: The utility of polymeric micelles formed through the multimolecular assembly of block copolymers as novel core-shell typed colloidal carriers for drug and gene targeting and their feasibility as non-viral gene vectors is highlighted.
Journal ArticleDOI
A new class of polymers: Starburst-dendritic macromolecules
Donald A. Tomalia,H. Baker,James R Dewald,Michael B. Hall,G. Kallos,Steven J. Martin,J. Roeck,J. Ryder,Patrick B. Smith +8 more
TL;DR: Starburst polymers as mentioned in this paper are a class of topological macromolecules which are derived from classical monomers/oligomers by their extraordinary symmetry, high branching and maximized terminal functionality density.
Related Papers (5)
Dendrimers in biomedical applications--reflections on the field.
Sonke Svenson,Donald A. Tomalia +1 more