Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT
Donald L. Budenz,Douglas R. Anderson,Rohit Varma,Joel S. Schuman,Louis B. Cantor,Jonathan Savell,David S. Greenfield,Vincent Michael Patella,Harry A. Quigley,James M. Tielsch +9 more
Reads0
Chats0
TLDR
Retinal nerve fiber layer thickness, as measured by Stratus OCT, varies significantly with age, ethnicity, axial length, and optic disc area, and these variables may need to be taken into account when evaluating patients for diagnosis and follow-up of glaucoma.About:
This article is published in Ophthalmology.The article was published on 2007-06-01 and is currently open access. It has received 634 citations till now. The article focuses on the topics: Optic disk & Optic disc.read more
Citations
More filters
Journal ArticleDOI
Glaucomatous damage of the macula
Donald C. Hood,Ali S. Raza,Carlos Gustavo De Moraes,Carlos Gustavo De Moraes,Jeffrey M. Liebmann,Jeffrey M. Liebmann,Robert Ritch,Robert Ritch +7 more
TL;DR: Clinicians need to be aware that glaucomatous damage to the macula is common, can occur early in the disease, and can be missed and/or underestimated with standard VF tests that use a 6° grid, such as the 24-2 VF test.
Journal ArticleDOI
A framework for comparing structural and functional measures of glaucomatous damage
Donald C. Hood,Randy H. Kardon +1 more
TL;DR: A framework is proposed for understanding what is meant by the question, 'Does structural damage precede functional damage in glaucoma?' and the need to distinguish between "statistical" and "relational" meanings of this question.
Journal ArticleDOI
Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis
Axel Petzold,Johannes F. de Boer,Sven Schippling,Patrik Vermersch,Randy H. Kardon,Ari J. Green,Peter A. Calabresi,Chris H. Polman +7 more
TL;DR: The estimated RNFL thinning in patients with MS is greater than the extent expected in normal ageing, probably because of retrograde trans-synaptic degeneration and progressive loss of retinal ganglion cells, in addition to the more pronounced thinning caused by optic neuritis if present.
Journal ArticleDOI
Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study.
Christopher Kai-Shun Leung,Carol Y. Cheung,Robert N. Weinreb,Quanliang Qiu,Quanliang Qiu,Shu Liu,Haitao Li,Guihua Xu,Guihua Xu,Ning Fan,Ning Fan,Lina Huang,Chi Pui Pang,Dennis S.C. Lam +13 more
TL;DR: Although the diagnostic performance and the strength of the structure-function association were comparable between Cirrus HD-OCT and Stratus OCT RNFL measurements, Cirrus' measurement variability demonstrated lower measurement variability compared withstratus OCT with significant differences at 1, 3, 4, and 8 to 11 o'clock.
Journal ArticleDOI
Optical Coherence Tomography Angiography Vessel Density in Healthy, Glaucoma Suspect, and Glaucoma Eyes.
Adeleh Yarmohammadi,Linda M. Zangwill,Alberto Diniz-Filho,Min Hee Suh,Patricia Isabel C. Manalastas,Naeem Fatehee,Siamak Yousefi,Akram Belghith,Luke J. Saunders,Felipe A. Medeiros,David Huang,Robert N. Weinreb +11 more
TL;DR: Optical coherence tomography angiography vessel density had similar diagnostic accuracy to RNFL thickness measurements for differentiating between healthy and glaucoma eyes, suggesting that OCT-A measurements reflect damage to tissues relevant to the pathophysiology of OAG.
References
More filters
Journal ArticleDOI
Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Book ChapterDOI
Optical Coherence Tomography
Eric A. Swanson,J. Izatt,M. Bee,David Huang,Charles P. Lin,Carmen A. Puliafito,Carmen A. Puliafito,James G. Fujimoto +7 more
TL;DR: Optical coherence tomography (OCT) has developed rapidly since its first realisation in medicine and is currently an emerging technology in the diagnosis of skin disease as mentioned in this paper, where OCT is an interferometric technique that detects reflected and backscattered light from tissue.
Journal ArticleDOI
The Ocular Hypertension Treatment Study: A Randomized Trial Determines That Topical Ocular Hypotensive Medication Delays or Prevents the Onset of Primary Open-Angle Glaucoma
Michael A. Kass,Dale K. Heuer,Eve J. Higginbotham,Chris A. Johnson,John L. Keltner,J. Philip Miller,Richard K. Parrish,M. Roy Wilson,Mae O. Gordon +8 more
TL;DR: Topical ocular hypotensive medication was effective in delaying or preventing the onset of POAG in individuals with elevated IOP, and clinicians should consider initiating treatment for individuals with ocular hypertension who are at moderate or high risk for developing POAG.
Journal ArticleDOI
Primary open-angle glaucoma.
Robert N. Weinreb,Peng T. Khaw +1 more
TL;DR: Improvements in therapy consist of more effective and better-tolerated drugs to lower intraocular pressure, and more effective surgical procedures to directly treat and protect the retinal ganglion cells that are damaged in glaucoma.
Journal ArticleDOI
Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma.
TL;DR: Estimates suggest that visual field sensitivity in automated testing begins to decline soon after the initial loss of ganglion cells in human eyes with glaucoma, and that this decline is most pronounced in areas that had 0-dB sensitivity in the field test.