Glaucomatous damage of the macula
Donald C. Hood,Ali S. Raza,Carlos Gustavo De Moraes,Carlos Gustavo De Moraes,Jeffrey M. Liebmann,Jeffrey M. Liebmann,Robert Ritch,Robert Ritch +7 more
TLDR
Clinicians need to be aware that glaucomatous damage to the macula is common, can occur early in the disease, and can be missed and/or underestimated with standard VF tests that use a 6° grid, such as the 24-2 VF test.About:
This article is published in Progress in Retinal and Eye Research.The article was published on 2013-01-01 and is currently open access. It has received 660 citations till now. The article focuses on the topics: Macula Lutea.read more
Citations
More filters
Journal ArticleDOI
Efficacy of a Deep Learning System for Detecting Glaucomatous Optic Neuropathy Based on Color Fundus Photographs.
TL;DR: A deep learning system can detect referable GON with high sensitivity and specificity and coexistence of high or pathologic myopia is the most common cause resulting in false-negative results.
Journal ArticleDOI
At the interface of sensory and motor dysfunctions and Alzheimer's disease
Mark W. Albers,Grover C. Gilmore,Jeffrey Kaye,Claire Murphy,Arthur Wingfield,David A. Bennett,Adam L. Boxer,Aron S. Buchman,Karen J. Cruickshanks,Davangere P. Devanand,Charles J. Duffy,Christine M. Gall,George A. Gates,Ann-Charlotte Granholm,Takao K. Hensch,Roee Holtzer,Bradley T. Hyman,Frank R. Lin,Ann C. McKee,John C. Morris,Ronald C. Petersen,Lisa C. Silbert,Robert G. Struble,John Q. Trojanowski,Joe Verghese,Donald A. Wilson,Shunbin Xu,Li I. Zhang +27 more
TL;DR: It is clear that sensory and motor regions of the central nervous system are affected by AD pathology and that interventions targeting amelioration of sensory‐motor deficits in AD may enhance patient function as AD progresses.
Journal ArticleDOI
Projection-Resolved Optical Coherence Tomography Angiography of Macular Retinal Circulation in Glaucoma
Hana L. Takusagawa,Liang Liu,Kelly N. Ma,Yali Jia,Simon S. Gao,Miao Zhang,Beth Edmunds,Mansi Parikh,Shandiz Tehrani,John C. Morrison,David Huang +10 more
TL;DR: Reflectance-compensated SVC VD measurement by PR-OCTA detected glaucoma with high accuracy and could be useful in the clinical evaluation of glAUcoma.
Journal ArticleDOI
Improving our understanding, and detection, of glaucomatous damage: An approach based upon optical coherence tomography (OCT).
TL;DR: It is illustrated that local thinning of the circumpapillary retinal nerve fiber layer around the optic disc can vary in location, depth, and/or width, as well as homogeneity of damage, and why one should expect a wide range of visual field patterns and why they should not be placed into discrete categories.
Journal ArticleDOI
Glaucoma: the retina and beyond.
Benjamin M. Davis,Laura Crawley,Milena Pahlitzsch,Fatimah Zara Javaid,Maria Francesca Cordeiro,Maria Francesca Cordeiro +5 more
TL;DR: The current understanding of the potential mechanisms underlying RGC and axonal loss in glaucoma is outlined, and an overview of recent developments in techniques for monitoring RGC health is provided, including recent progress towards the development of RGC specific contrast agents.
References
More filters
Journal ArticleDOI
Topography of ganglion cells in human retina.
TL;DR: The spatial distribution of presumed ganglion cells and displaced amacrine cells in unstained whole mounts of six young normal human retinas whose photoreceptor distributions had previously been characterized was quantified, suggesting meridianal differences in convergence onto individual ganglION cells.
Journal ArticleDOI
Reproducibility of Nerve Fiber Layer Thickness Measurements Using Optical Coherence Tomography
Joel S. Schuman,Tamar Pedut-Kloizman,Ellen Hertzmark,Michael R. Hee,J. R. Wilkins,Jeffery G. Coker,Carmen A. Puliafito,James G. Fujimoto,Eric A. Swanson +8 more
TL;DR: Nerve fiber layer thickness can be reproducibly measured using OCT; internal is superior to external fixation; each circle diameter tested provides adequate reproducibility.
Journal ArticleDOI
Mapping the visual field to the optic disc in normal tension glaucoma eyes
TL;DR: A clinically useful map that relates visual field test points to regions of the optic nerve head (ONH) has been produced that will aid clinical evaluation of glaucoma patients and suspects, as well as form the basis for investigations of the relationship between retinal light sensitivity and ONH structure.
Journal ArticleDOI
Regional Differences in the Structure of the Lamina Cribrosa and Their Relation to Glaucomatous Optic Nerve Damage
Harry A. Quigley,Earl M. Addicks +1 more
TL;DR: Using a new technique for scanning electron microscopic examination of human optic nerve heads, regional differences were found in the fine structure of the lamina cribrosa that may explain the characteristic pattern of early glaucomatous field loss.
Journal ArticleDOI
Determinants of Normal Retinal Nerve Fiber Layer Thickness Measured by Stratus OCT
Donald L. Budenz,Douglas R. Anderson,Rohit Varma,Joel S. Schuman,Louis B. Cantor,Jonathan Savell,David S. Greenfield,Vincent Michael Patella,Harry A. Quigley,James M. Tielsch +9 more
TL;DR: Retinal nerve fiber layer thickness, as measured by Stratus OCT, varies significantly with age, ethnicity, axial length, and optic disc area, and these variables may need to be taken into account when evaluating patients for diagnosis and follow-up of glaucoma.