Developing a Set of Core Outcomes for Trials in Hemodialysis: An International Delphi Survey.
Nicole Evangelidis,Nicole Evangelidis,Allison Tong,Allison Tong,Braden Manns,Brenda R. Hemmelgarn,David C. Wheeler,Peter Tugwell,Sally Crowe,Tess Harris,Wim Van Biesen,Wolfgang C. Winkelmayer,Bénédicte Sautenet,Donal O'Donoghue,Helen Tam-Tham,Sajeda Youssouf,Sreedhar Mandayam,Angela Ju,Angela Ju,Carmel M. Hawley,Carmel M. Hawley,Carol A. Pollock,David Harris,David W. Johnson,David W. Johnson,Dena E. Rifkin,Francesca Tentori,John W M Agar,Kevan R. Polkinghorne,Martin Gallagher,Peter G. Kerr,Stephen P. McDonald,Stephen P. McDonald,Kirsten Howard,Martin Howell,Martin Howell,Jonathan C. Craig,Jonathan C. Craig +37 more
TLDR
A consensus-based prioritized list of core outcomes for trials in hemodialysis will improve the relevance, efficiency, and comparability of trial evidence to facilitate treatment decisions and patients/caregivers gave higher priority to lifestyle-related outcomes than health professionals.About:
This article is published in American Journal of Kidney Diseases.The article was published on 2017-10-01 and is currently open access. It has received 187 citations till now. The article focuses on the topics: Health care & Family caregivers.read more
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Australian Workshops on Patients’ Perspectives on Hemodialysis and Incremental Start
K. Hegerty,A. Jaure,Nicole Scholes-Robertson,Kirsten Howard,Angela Ju,Nicole Evangelidis,Martin Wolley,Amanda Baumgart,David W. Johnson,Carmel M. Hawley,Donna Reidlinger,Laura E. Hickey,Alyssa Welch,Yeoungjee Cho,Peter G. Kerr,Matthew A Roberts,Jenny I. Shen,Jonathan C. Craig,Rathika Krishnasamy,Andrea K. Viecelli +19 more
TL;DR: Patients with kidney failure preferred an incremental start to HD to minimize disruption to daily living and reduce the negative impacts on their education, ability to work, and family life as discussed by the authors .
Journal ArticleDOI
Nutrition impact symptom clusters in a cohort of Indigenous Australian hemodialysis patients: new insights into the management of malnutrition?
TL;DR: Malnourished patients experienced a significantly greater symptom burden in this study, and the small evidence base about the nutrition impact symptom burden of Indigenous hemodialysis patients is extended.
Journal ArticleDOI
Study protocol for Vascular Access outcome measure for function: a vaLidation study In hemoDialysis (VALID)
Andrea K. Viecelli,Armando Teixeira-Pinto,Andrea Valks,Richard Baer,Roy Cherian,Pietro E. Cippà,Jonathan C. Craig,Ranil DeSilva,A. Jaure,David W. Johnson,Charani Kiriwandeniya,Pascal Kopperschmidt,Timmy Lee,Charmaine E. Lok,Krishan K. Madhan,Alistair R. Mallard,Veronica Oliver,Kevan R. Polkinghorne,Robert R. Quinn,Donna Reidlinger,Matthew A Roberts,Bénédicte Sautenet,Lai Seong Hooi,Rob Smith,Maarten G. J. Snoeijs,J. Tordoir,Tushar J. Vachharajani,Raymond Vanholder,Liza A. Vergara,Martin Wilkie,Bing Yang,Theodore H. Yuo,Li-Ling Zou,Carmel M. Hawley,Laura Robison,Alyssa Welch,Sunil Badve,Neil Boudville,Katrina L. Campbell,Yeoungjee Cho,Michael Collins,Magid Fahim,Meg Jardine,Dianne Du Toit,Michelle Mayne,Kim Stevenson,Rachel Kalpana James,Quynh Vu,Karyn Allen,Leanne Glancy,Jijo Kumbikkal,Sharan Burton,Lisa E. Gordon,Kyle Matthew McCarthy,Cathy Forrester,Sally E. Lima,O. Bourgault,Claire Drouault,Fanny Teasdale,Liu Wen Jiun,Jamian Abidin,Cheng Jin Kiang,Lee Soon Leng,Yuana Mohd Yusoff,Adriana Ciochina,Magda M. van Loon,Ronald Ophelders,Marie-José Vleugels,P. Ferrari,Marie Brodeur,Davide Giunzioni,Christine Bressan Molfese,Chris Blackwell,Louese Dunn,Laura M. Gillis,Barry Gray,Sarah Jenkins +76 more
TL;DR: A validated, patient-important outcome measure for vascular access (VA) that can be easily measured in research and practice to harvest reliable and relevant evidence for informing patient-centered hemodialysis care is lacking as discussed by the authors .
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Treatment decision-making and care among older adults with kidney failure: protocol for a multicentre, prospective observational cohort study with nested substudies and linked qualitative research (the Elderly Advanced CKD Programme)
Amanda N. Siriwardana,Nicholas A Gray,Angela Makris,Chenlei Li,Kenneth Yong,Yachna Mehta,J. Ramos,Gian Luca Di Tanna,Chris Gianacas,I. Y. Addo,Sarah Roxburgh,Vasi Naganathan,Celine Foote,Martin Gallagher +13 more
TL;DR: The Outcomes of Older patients with Kidney failure (OUTLOOK) as discussed by the authors is a multicentre prospective observational cohort study that will enrol 800 patients ≥75 years with kidney failure across a minimum of six sites in Australia.
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A Delphi Study to Prioritize Evidence-Based Strategies for Cardiovascular Disease Care in India
Kavita Singh,Nikhil Srinivasapura Venkateshmurthy,Rahul Rahul,Mark D. Huffman,Nikhil Tandon,Dorairaj Prabhakaran +5 more
TL;DR: In this article , the authors identified and prioritized evidence-based quality improvement strategies for CVD care in India using a modified two-round Delphi process in which, they asked 46 experts (clinicians, researchers, program implementers and policy makers) to rate 25 proven clinical care strategies grouped into: (1) patient support, (2) information communication technology (ICT), (3) group problem solving, (4) training, and (5) multicomponent strategy on a scale of 1 (highest/best)-5 (lowest/worst) on priority, relative advantage, and feasibility.
References
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An Experimental Application of the Delphi Method to the Use of Experts
Norman Crolee Dalkey,Olaf Helmer +1 more
TL;DR: The DELPHI method was devised in order to obtain the most reliable opinion consensus of a group of experts by subjecting them to a series of questionnaires in depth interspersed with controlled opinion feedback as mentioned in this paper.
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Avoidable waste in the production and reporting of research evidence
Iain Chalmers,Paul Glasziou +1 more
TL;DR: “Research results should be easily accessible to people who need to make decisions about their own health...
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How to increase value and reduce waste when research priorities are set
Iain Chalmers,Michael B. Bracken,Ben Djulbegovic,Silvio Garattini,Jonathan Grant,A Metin Gülmezoglu,David W. Howells,John P. A. Ioannidis,Sandy Oliver +8 more
TL;DR: This report discusses how avoidable waste can be considered when research priorities are set and recommends ways to improve the yield from basic research, and the transparency of processes by which funders prioritise important uncertainties should be increased.
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Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis
Evolve Trial Investigators,Glenn M. Chertow,Geoffrey A. Block,Ricardo Correa-Rotter,Tilman B. Drüeke,J. Floege,William G. Goodman,Charles A. Herzog,Yumi Kubo,Gérard M. London,Kenneth W. Mahaffey,Mix Tc,Sharon M. Moe,Marie-Louise Trotman,David C. Wheeler,Patrick S. Parfrey +15 more
TL;DR: In an unadjusted intention-to-treat analysis, cinacalcet did not significantly reduce the risk of death or major cardiovascular events in patients with moderate- to-severe secondary hyperparathyroidism who were undergoing dialysis.
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Developing Core Outcome Measurement Sets for Clinical Trials: OMERACT Filter 2.0
Maarten Boers,John R. Kirwan,George A. Wells,Dorcas E. Beaton,Laure Gossec,Maria Antonietta D'Agostino,Philip G. Conaghan,Clifton O. Bingham,Peter Brooks,Robert Landewé,Lyn March,Lyn March,Lee S. Simon,Jasvinder A. Singh,Jasvinder A. Singh,Vibeke Strand,Peter Tugwell +16 more
TL;DR: The OMERACT Filter 2.0 explicitly describes a comprehensive conceptual framework and a recommended process to develop core outcome measurement sets for rheumatology likely to be useful as a template in other areas of health care.
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