Differential patterns of cortical reorganization following constraint-induced movement therapy during early and late period after stroke: A preliminary study.
Lumy Sawaki,Andrew J. Butler,Xiaoyan Leng,Peter A. Wassenaar,Yusif Mohammad,Sarah Blanton,Krishnankutty Sathian,Deborah S. Nichols-Larsen,Steven L. Wolf,David C. Good,George F. Wittenberg +10 more
TLDR
CIMT appears to lead to greater improvement in motor function in the early phase after stroke, and the contrast between larger functional gains in theEarly group vs larger map changes in the late group may indicate that mechanisms of recovery change over the several months following stroke or that map changes are a time-dependent epiphenomenon.Abstract:
OBJECTIVE
Constraint-induced movement therapy (CIMT) leads to improvement in upper extremity movement and cortical reorganization after stroke. Direct comparison of the differential degree of cortical reorganization according to chronicity in stroke subjects receiving CIMT has not been performed and was the purpose of this study. We hypothesized that a higher degree of cortical reorganization would occur in the early (less than 9 months post-stroke) compared to the late group (more than 12 months post-stroke).read more
Citations
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Journal ArticleDOI
Spontaneous and Therapeutic-Induced Mechanisms of Functional Recovery After Stroke
TL;DR: Sp spontaneous and therapeutic-induced mechanisms driving post-stroke functional recovery are discussed while underscoring several potential restorative therapies and biomarkers.
Journal ArticleDOI
Dose and timing in neurorehabilitation: prescribing motor therapy after stroke.
TL;DR: It is suggested that substantially more movement practice may be necessary to achieve better outcomes for people living with the disabling consequences of stroke and clinical investigations are needed to determine the dose-response relationships and examine the potential dose-timing interaction in humans.
Journal ArticleDOI
Constraint‐induced movement therapy for upper extremities in people with stroke
TL;DR: CIMT was associated with limited improvements in motor impairment and motor function, but that these benefits did not convincingly reduce disability, differs from the result of the previous meta-analysis where there was a suggestion that CIMT might be superior to traditional rehabilitation.
Journal ArticleDOI
TMS measures of motor cortex function after stroke: A meta-analysis
TL;DR: The neurophysiological effects of stroke are primarily localised to the affected hemisphere, and there is no clear evidence for hyper-excitability of the unaffected hemisphere or imbalanced interhemispheric inhibition, which indicates that facilitating affected M1 excitability directly may be more beneficial than suppressing unaffected M2 excitability for promoting post-stroke recovery.
Journal ArticleDOI
Skilled Bimanual Training Drives Motor Cortex Plasticity in Children With Unilateral Cerebral Palsy.
Kathleen M. Friel,Kathleen M. Friel,Hsing-Ching Kuo,Jason R. Fuller,Claudio L Ferre,Marina de Brito Brandão,Jason B. Carmel,Yannick Bleyenheuft,Jaimie Gowatsky,Arielle D. Stanford,Stefan B. Rowny,Bruce Luber,Bruce D. Bassi,David L. K. Murphy,Sarah H. Lisanby,Andrew M. Gordon +15 more
TL;DR: These findings uncover a dichotomy of plasticity: the unstructured practice group improved hand function but did not show changes in motor maps, which is important for driving motor cortex plasticity in children with USCP.
References
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Journal ArticleDOI
Heart Disease and Stroke Statistics—2007 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Wayne D. Rosamond,Katherine M. Flegal,Gary Friday,Karen L. Furie,Alan S. Go,Kurt J. Greenlund,Nancy Haase,Michael Ho,Virginia J. Howard,Bret Kissela,Steven J. Kittner,Donald M. Lloyd-Jones,Mary M. McDermott,James B. Meigs,Claudia S. Moy,Graham Nichol,Christopher J. O'Donnell,Véronique L. Roger,John S. Rumsfeld,Paul D. Sorlie,Julia Steinberger,Thomas Thom,Sylvia Wasserthiel-Smoller,Yuling Hong +23 more
TL;DR: This chapter describes the most important sources and the types of data the AHA uses from them and other government agencies to derive the annual statistics in this Update.
Journal ArticleDOI
Heart Disease and Stroke Statistics—2008 Update A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Wayne Rosamond,Katherine M. Flegal,Karen L. Furie,Alan S. Go,Kurt J. Greenlund,Nancy Haase,Susan M. Hailpern,Michael Ho,Virginia J. Howard,Bret Kissela,Steven J. Kittner,Donald M. Lloyd-Jones,Mary M. McDermott,James B. Meigs,Claudia S. Moy,Graham Nichol,Christopher J. O'Donnell,Véronique L. Roger,Paul D. Sorlie,Julia Steinberger,Thomas Thom,Matthew Wilson,Yuling Hong +22 more
TL;DR: Each year the American Heart Association brings together the most up-to-date statistics on heart disease, stroke, and their risk factors and presents them in its Heart Disease and Stroke Statistical Update.
Book
Motor Control and Learning: A Behavioral Emphasis
TL;DR: This chapter discusses the evolution of a field of study, methodology for Studying, and methods for studying human information processing and motor learning.
Journal ArticleDOI
Non-invasive electrical and magnetic stimulation of the brain, spinal cord and roots: basic principles and procedures for routine clinical application. Report of an IFCN committee
Paolo Maria Rossini,A.T. Barker,Alfredo Berardelli,Maria D. Caramia,Giuseppe Caruso,Roger Q. Cracco,Milan R. Dimitrijevic,Mark Hallett,Yoichi Katayama,Carl Hermann Lücking,A. Maertens de Noordhout,C. D. Marsden,N. M. F. Murray,John C. Rothwell,Michael Swash,C. Tomberg +15 more
TL;DR: This year's jurors included A.M.
Journal ArticleDOI
Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation After Brain Damage
TL;DR: 10 principles of experience-dependent neural plasticity and considerations in applying them to the damaged brain are reviewed from the perspective of basic neuroscientists but in a manner intended to be useful for the development of more effective clinical rehabilitation interventions.