Journal ArticleDOI
Differentiation of neuronal stem cells into motor neurons using electrospun poly-L-lactic acid/gelatin scaffold.
Loïc Binan,Charlène Tendey,Gregory De Crescenzo,Rouwayda El Ayoubi,Abdellah Ajji,Mario Jolicoeur +5 more
TLDR
It is elucidated that a combination of electrospun fiber scaffolds, neural stem cells, and controlled delivery of instructive cues could lead to the development of a better strategy for peripheral nerve injury repair.About:
This article is published in Biomaterials.The article was published on 2014-01-01. It has received 114 citations till now. The article focuses on the topics: Neural stem cell & Purmorphamine.read more
Citations
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Journal ArticleDOI
Poly(lactic acid) nanofibrous scaffolds for tissue engineering.
TL;DR: The latest advances in the use of PLA nanofibrous scaffolds for musculoskeletal, nervous, cardiovascular, and cutaneous tissue engineering are presented and perspectives on their future use are offered.
Journal ArticleDOI
Electrospinning versus microfluidic spinning of functional fibers for biomedical applications.
TL;DR: An overview of the two spinning methods including the spinning principle, their unique features and materials selections are presented and several applications of fibers spun by both methods, especially in tissue engineering, organ function regeneration and drug delivery are introduced.
Journal ArticleDOI
Electrospinning: An enabling nanotechnology platform for drug delivery and regenerative medicine.
TL;DR: How the 3D printing technology can contribute to the improvement of traditional electrospinning technology for the fabrication of 3D electrospun nanofiber materials as drug delivery devices/implants, scaffolds or living tissue constructs is emphasized.
Journal ArticleDOI
Current and novel polymeric biomaterials for neural tissue engineering
TL;DR: Most of neural tissue engineering applications are in pre-clinical study, in particular for use in the central nervous system, however collagen polymer conduits aimed at regeneration of peripheral nerves have already been successfully tested in clinical trials.
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Current advances in electrospun gelatin-based scaffolds for tissue engineering applications
TL;DR: In this mini-review, electrospun gelatin-based scaffolds for a variety of tissue engineering applications, such as bone, cartilage, skin, nerve, and ocular and vascular tissue engineering, are reviewed and discussed.
References
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Journal ArticleDOI
Hydrogels in drug delivery: progress and challenges
Todd Hoare,Daniel S. Kohane +1 more
TL;DR: Recent progress in overcoming challenges with regards to effectively delivering hydrogels inside the body without implantation, prolonging the release kinetics of drugs fromhydrogels, and expanding the nature of drugs which can be delivered using hydrogel-based approaches is discussed.
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Electrospinning: Applications in drug delivery and tissue engineering
TL;DR: This review summarizes the most recent and state of the art work in electrospinning and its uses in tissue engineering and drug delivery and its ability to fabricate fibers with diameters on the nanometer size scale.
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In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
TL;DR: An in vivo genetic fate-mapping strategy is adopted, using Gli1 (GLI-Kruppel family member) as a sensitive readout of Shh activity, to systematically mark and follow the fate of ShH-responding cells in the adult mouse forebrain.
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The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation
TL;DR: C cultured rat hippocampus-derived adult NSCs on laminin-coated electrospun Polyethersulfone fiber meshes with average fiber diameters indicated fiber topography can play a vital role in regulating differentiation and proliferation of rNSCs in culture.