Does regional anaesthesia and analgesia or opioid analgesia influence recurrence after primary cancer surgery? An update of available evidence
TLDR
Just how anaesthesia and analgesia impact cancer recurrence and consequent survival is very topical, as understanding the potential mechanisms and interactions has an impact on the anaesthetist's ability to contribute to the successful outcome of oncological interventions.About:
This article is published in Best Practice & Research Clinical Anaesthesiology.The article was published on 2013-12-01 and is currently open access. It has received 51 citations till now. The article focuses on the topics: Perioperative.read more
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Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice
Aarne Feldheiser,O. Aziz,Gabriele Baldini,B Cox,Kch C. H. Fearon,Ls S. Feldman,Tj J. Gan,Rh H. Kennedy,Olle Ljungqvist,Dn N. Lobo,Timothy E. Miller,Ff F. Radtke,T. Ruiz Garces,T. Schricker,Mj J. Scott,Jk K. Thacker,Lm M. Ytrebø,Franco Carli +17 more
TL;DR: Clinical considerations and recommendations for anaesthetic practice in patients undergoing gastrointestinal surgery with an Enhanced Recovery after Surgery (ERAS) programme are proposed.
Journal ArticleDOI
Can anesthetic-analgesic technique during primary cancer surgery affect recurrence or metastasis?
TL;DR: Current laboratory research suggests that perioperative interventions may impact recurrence or metastasis through effects on cancer cell signalling, the immune response, or modulation of the neuroendocrine stress response.
Journal ArticleDOI
Perioperative Anesthesia Care and Tumor Progression.
TL;DR: In this paper, the authors discuss the most recent up-to-date findings focused on the currently available "best clinical practice" regarding perioperative anesthesia care bundle factors and their effect on tumor progression.
Identification of early-stage colorectal cancer patients at risk of relapse post-resection by immunobead reverse transcription-PCR analysis of peritoneal lavage fluid for malignant cells
Julia M. Lloyd,Cassandra M. McIver,Sally-Anne Stephenson,Peter Hewett,Nicholas Rieger,Jennifer E. Hardingham +5 more
TL;DR: In this paper, tumor-associated markers were used to detect disseminated malignant cells and identify a subgroup of patients with early-stage colorectal cancer that were at risk of relapse.
Journal ArticleDOI
Anesthetic technique and cancer recurrence in oncologic surgery: unraveling the puzzle.
TL;DR: Preclinical and retrospective studies highlight a potential benefit of anesthetic technique in reducing cancer-related mortality and recurrence by attenuating immunosuppression following surgical treatment in patients with specific types of cancer.
References
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The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited
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Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer
Franck Pagès,Anne Berger,Matthieu Camus,Fátima Sánchez-Cabo,Anne Costes,Robert Molidor,Bernhard Mlecnik,Amos Kirilovsky,Malin Nilsson,Diane Damotte,Tchao Meatchi,Patrick Bruneval,Paul-Henri Cugnenc,Zlatko Trajanoski,Wolf H. Fridman,Jérôme Galon +15 more
TL;DR: Signs of an immune response within colorectal cancers are associated with the absence of pathological evidence of early metastatic invasion and with prolonged survival.
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Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
TL;DR: The characterization and suppressive mechanisms used by myeloid-derived suppressor cells to block tumor immunity are reviewed and the mechanisms by which inflammation promotes tumor progression through the induction of MDSC are described.
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Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial.
Jack Cuzick,Ivana Sestak,Michael Baum,Aman U. Buzdar,Anthony Howell,Mitch Dowsett,John F. Forbes +6 more
TL;DR: The Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial as discussed by the authors was designed to compare the efficacy and safety of anastrozole (1 mg) with tamioxifen (20 mg) as adjuvant treatment for postmenopausal women with early stage breast cancer.
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