Journal ArticleDOI
Early administration of intravenous magnesium to high-risk patients with acute myocardial infarction in the Magnesium in Coronaries (MAGIC) Trial: a randomised controlled trial.
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TLDR
Early administration of magnesium in high-risk patients with STEMI has no effect on 30-day mortality, and in current coronary care practice there is no indication for the routine administration of intravenous magnesium in patients withSTEMI.About:
This article is published in The Lancet.The article was published on 2002-10-19. It has received 163 citations till now. The article focuses on the topics: Placebo & Reperfusion therapy.read more
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Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
Jonathan A C Sterne,Alex J. Sutton,John P. A. Ioannidis,Norma Terrin,David R. Jones,Joseph Lau,James R. Carpenter,Gerta Rücker,Roger M. Harbord,Christopher H. Schmid,Jennifer Tetzlaff,Jonathan J Deeks,Jaime Peters,Petra Macaskill,Guido Schwarzer,Sue Duval,Douglas G. Altman,David Moher,Julian P T Higgins +18 more
TL;DR: How to interpret funnel plot asymmetry, recommends appropriate tests, and explains the implications for choice of meta-analysis model are described.
Journal ArticleDOI
Myocardial Reperfusion Injury
TL;DR: This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention.
Journal ArticleDOI
2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
Sana M. Al-Khatib,William G. Stevenson,Michael J. Ackerman,William J. Bryant,David J. Callans,Anne B. Curtis,Barbara J. Deal,Timm Dickfeld,Michael E. Field,Gregg C. Fonarow,Anne M. Gillis,Christopher B. Granger,Stephen C. Hammill,Mark A. Hlatky,Jose A. Joglar,G. Neal Kay,Daniel D. Matlock,Robert J. Myerburg,Richard L. Page +18 more
TL;DR: The next chair and vice-chair will be announced at a special meeting of the American Academy of Anti-Accident and Accident Medicine (AACC) board of directors in New York later this month.
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Magnesium in Man: Implications for Health and Disease
TL;DR: An extensive and comprehensive overview of Mg(2+) research over the last few decades is provided, focusing on the regulation of M g(2+) homeostasis in the intestine, kidney, and bone and disturbances which may result in hypomagnesemia.
Journal ArticleDOI
Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial
Shamir R. Mehta,Salim Yusuf,Rafael Diaz,Jun Zhu,Prem Pais,Denis Xavier,Ernesto Paolasso,Rashid J. Ahmed,Changchun Xie,Khawar Kazmi,Javed Tai,Andrés Orlandini,Janice Pogue,Lisheng Liu,L. Cronin,Rakesh Gupta,K. K. Haridas,T. M. Jaison,Prashant P. Joshi,Prafulla Kerkar,A. K. Maity,S. C. Manchanda,Sudhir Naik,Dorairaj Prabhakaran,Seemala Saikrishna Reddy,Bateshwar Prasad Singh,S. Thanikachalam,D. Xavier,X. J. Bai,T. Chen,J. J. Cui,T. X. Cui,S. Y. Fu,H. Ge,Q. L. Li,S. M. Li,W. Li,Y. Q. Li,L. Liu,Y. H. Liu,Z. R. Lu,S. P. Ma,D. Qiao,Y. C. Song,N. L. Sun,L. H. Wang,S. W. Wang,W. Wang,Y. Wang,N. Wu,Y. S. Wu,C. B. Xu,S. C. Xu,Z. M. Xu,G. J. Yang,H. S. Yang,C. Z. Zhang,S. T. Zhang,W. J. Zhang,J. C. Zhou,J. Zhu,Wael Almahmeed,Alvaro Avezum,P. Castro,Ramón Corbalán,R. Pitarch Flors,B. M. Lombana,L. Marano,Darren K. McGuire,E. Paolasso,J. E. Isea Perez,L. Soares Piegas,F. Van de Werf,Harvey D. White,Mohammad Zubaid,A. M. Faruqi,I. Rasool,K. Soomro,H. ul Banna,S. Yusuf,S. R. Mehta,R. J. Ahmed,S. Pavlov,J. Pogue,F. Zhao,I. Tsuluca,M. Molec,I. Holadyk-Gris,K. Ahmed,P. Pais,D. Freeda,S. Lidwin,M. Chenniappan,B. Isaac,S. S. Iyengar,Pradeep Joshi,Shriprakash Kalantri,Susmita Kaushik,U. K. Mahorkar,J. Narendra,Sanjoy K. Paul,M. J. Santhosh,B. K.S. Sastry,S. B. Siwach,K. Varghese,H. Yang,Y. Yang,X. Zhang,H. Tan,J. Tang,X. Li,L. Yan,Y. Zhang,J. Li,M. Y. Bai,Y. Q. Jiang,S. Y. Lang,X. Y. Shi,Z. R. Tian,K. Wang,D. H. Yan,S. Y. Yu,Álvaro Pascual,H. Ozcoidi,Carmen de la Cuesta,D. Wojdyla,G. M. Font,M. I. Genisans,I. Chandna,M. Rafiq,N. Dadani,S. S. Fatima,S. Rehman,S. Adil,K. Bhojomal,Abdul Hameed,S. A. Khan,P. Sleight,C. Baigent,Jack Hirsh,W. Taylor,G. Tognoni,P. Bacher,N. Bender,U. Legler,U. Magin,U. Raschke,M. San Mauro,M. A. Brito,A. Alves De Lima,R. A. Ahuad Guerrero,R. Nordaby,R. J. Barcudi,J. Bono,R. E. Ledesma,H. R. Ramos,A. Caccavo,S. M. Macin,S. N. Ferreyra Cantante,G. D. Caime,L. R. Cartasegna,O. A. Perrino,A. J. Gambarte,E. Marzetti,M. Garrido,R. J. Balado,Cláudia B.R. Martinez,A. A. Fernandez,E. Ferro Queirel,J. O. Balbi,G. Amuchastegui,G. Covelli,A. Gentile,C. E. Girino,Job E. Lopez,R. Monti,A. D. Orlandini,O. Pellizon,J L Ramos,G. Zapata,C. A. Cuneo,J. A. Sanchez,J. P. Albisu,M. A. Berli,M. A. Hominal,R. A. Peleteiro Mariño,V. Mezzina,E. M. Avila,P. Baselga,C. R. Castellanos,H. L. Luciardi,L. L. Lobo Marquez,J. Muntaner,E. M. Good God,G. Reis,D. M. Mello Soares,Luiz Carlos Bodanese,E. Manenti,L. Prestes,J. G. De Castro Amino,R. Uchoa Azevedo,Antonio Carlos Carvalho,R. F. Ramos,M. Alcaino,P. Castro Galvez,R. Corbalán Herreros,H. Liu,R. Wang,Z. C. Liu,X. Tian,G. Wang,Z. Nan,J. Zhang,C. Zai,W. Chen,M. Gao,D. Hu,S. Jia,D. X. Li,Q. Li,S. L. Liu,Y. Sun,B. Wang,G. F. Xie,Z. Xu,X. Yang,M. Zhao,X. Zhao,Z. Fang,S. Y. Liu,Z. Ma,Y. Jiang,Z. Zhen,F. Huo,H. G. Yang,Y. Miao,C. M. Yang,X. Chi,Z. X. Liu,S. Zhou,F. S. Zhou,R. Guo,K. Jing,S. Ren,J. Zhao,H. Bai,C. Cheng,J. Cheng,X. Hao,H. Li,W. G. Li,S. Wang,W. Zhang,L. Li,S. Fu,J. Shao,X. Tan,S. Chen,J. Fu,Q. Zheng,J. Ma,H. Chen,H. Ma,L. Gong,Z. Zhang,F. Li,B. Yang,L. S. Zhou,Z. Wang,X. Sun,G. Tao,Q. Wang,X. Guo,X. Wang,K. Zai,Q. Cui,S. Fan,W. Liu,Q. Meng,G. Qi,Y. Qin,N. Wang,G. Xu,X. Yin,Q. Zhang,S. Zhang,R. Liu,F. Wang,W. K. Li,H. Zhang,X. Xu,R. Ma,F. Guan,T. Yang,R. Zhqo,J. Huang,A. Li,J. Zhou,X. You,L. Hao,F. Zhangfang,X. Ma,C. Shen,Z. Hou,N. F. Zho,G. Huang,P. Guo,J. Lou,Q. P. Wang,X. Jiang,Z. Li,D. Tian,Z. D. Wu,M. G. Yang,Z. C. Li,S. G. Yang,Y. Tu,C. He,Y. Cao,Y. Han,Jinhai Yang,S. Dong,D. F. Li,Q. F. Zhang,Z. Fan,D. Q. An,J. Liu,G. Yang,X. C. Xu,Y. Xia,H. Xu,T. Wang,D. Li,J. Wei,P. Yang,C. Y. Liu,S. Shang,Y. G. Zhang,E. Hernandez Leyva,N. Cano Lopez,A. R. Gonzalez Medina,John Kanakakis,John N. Nanas,P. Papazoglou,J. Srinivas,B. Srinivasulu,S. Dani,J. Prajapati,G. Deepak,J. F. Shallam,K. J. Nesaraj,Ashok Kumar,Rinku Sharma,S. Balasubramaniyan,N. Chidambaram,R. Umrani,Sharad Chandra,S. Dwivedi,R. Kishore,B. J. Kumar,Y. Kumble,S. Mehrotra,P. R. Nayak,S. S. Ramesh,P. K. Shetty,S. K. Trivedi,R. Beniwal,A. Kalla,R. B. Panwar,K. G. Alexander,A. V. Bindu,A. Nambiar,D. Barkavi,A. Kalanidhi,T. Pradeep,J. Rajesh,M. Ramesh,S. Shanmugasundaram,Pradeep Kumar,G. Sidhu,Rajvir Singh,K. N. Pradeep,Anubhav Mittal,J. B. Bijapure,M. S. Rao,N. G. Mohanarjun,M. B. Rao,B. R. Babu,N. Dinesh,R. K. Jain,P. A. Jiwani,S. R. Naik,T. N.C. Padmanabhan,B. S. Raju,R. Rajaram,A. S.V.N. Rao,DC Rao,V. S.P. Rao,S. Sinha,A. Bharani,G. Verma,R. K. Tongia,Sanjay Kalra,Shweta Sharma,Ravi Mehrotra,S. Sanghvi,O. P. Soni,Atanu Biswas,J. Boben,G. Jacob,Johny Joseph,A. Puri,V. K. Puri,H. Singh,R. Calton,G. K. Aneja,P. Nyayadhish,P. J. Nathani,S. K. Rane,M. Fulwani,A. S. Jain,Amal Kumar Khan,R. G. Salkar,A. Somani,R. Wadhwani,S. D. Zawar,V. E. Shegokar,S. L. Tungikar,V. Vijan,R. Trehan,A. Garg,S. Verma,S. Borade,D. Duggal,J. Hiremath,Jagdish,V.K. Katyal,H. R. Devendrappa,Ratnakar,P. B. Latha,E. B. Manoj,P.P. Mohanan,P. Gandhimadhinathan,K. Jeremaiah,B. S.V. Raj,R. Udaysankar,J. K. Chhaparwal,S. T. Chandy,Sonia Gupta,S. Raghavan,P. Ramesh,V. S. Reddy,P. Srinivas,K. D. Rao,B. R. Malipeddi,G. S.R. Murthy,Rajnish Joshi,Supriya Patil,S. Tredici,D. Agnelli,E. Assanelli,A. Bozzano,L. Marsano,R. Crivello,A. Nejrotti,A. Abdulminem,H. Saad,J. Martinez Sanchez,J. Carrillo Calvillo,A. Hamer,H. U. Banna,J. Lopez Ferre,R. J. Freedman,N. Transk,D. Almeida,P. J.C. Lujan,C. Mata,C. Becerra,Kadir González,F. Torres,M. A. Alvarez,E. Carrillo +481 more
TL;DR: In this large, international randomized trial, high-dose GIK infusion had a neutral effect on mortality, cardiac arrest, and cardiogenic shock in patients with acute STEMI.
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ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group.
Rory Collins,Richard Peto,Marcus Flather,Sarah Parish,Peter Sleight,M Conway,A Pipilis,Colin Baigent,D Barnett,J P Boissel,Andrzej Budaj,John A. Cairns,L Ceremuzynski,Alexander T. Cohen,G Debacker,Rafael Diaz,F Dienstl,P Dove,MariaGrazia Franzosi,Genoni M,D Halon,J Heikkila,Charles H. Hennekens,J Horgan,D Hunt,R Kala,N Karatzas,Anthony C Keech,Matyas Keltai,J Kjekshus,M Kornitzer,R Koster,P Landless,P Lechleitner,Alain Leizorovicz,B Lewis,L Lundkvist,Stephen MacMahon,Aldo P. Maggioni,R Malacrida,T Meyer,Tiziano Moccetti,D Ocallaghan,Ernesto Paolasso,Leopoldo S. Piegas,A Reikvam,Paul M. Ridker,T Ryan,R Schroder,R Seabragomes,J Sousa,G Tognoni,Alexander G.G. Turpie,Valentin,J Varigos,H White,L Wilhelmsen,K Woods,Salim Yusuf,A Piombo,L Guzman,D Montenegro,G Irusta,R Schneider,C Cuneo,B Chamorro,G Espinosa,M Moreno,M Rios,Richard Doll,Keith A.A. Fox,D Julian,P Meier,E Sandoya,J Perez +74 more
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TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy.
David A. Morrow,Elliott M. Antman,Andrew Charlesworth,Richard Cairns,Sabina A. Murphy,James A. de Lemos,Robert P. Giugliano,Carolyn H. McCabe,Eugene Braunwald +8 more
TL;DR: The TIMI risk score for STEMI captures the majority of prognostic information offered by a full logistic regression model but is more readily used at the bedside, likely to be clinically useful in the triage and management of fibrinolytic-eligible patients with STEMI.
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