Journal ArticleDOI
Eco-friendly and Efficient Synthesis of Pyrano[2,3-d] pyrimidinone and Tetrahydrobenzo[b]pyran Derivatives in Water
TLDR
Tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone derivatives were synthesized efficiently in the presence of KAl(SO4)2.12H2O (alum) in water.Abstract:
Tetrahydrobenzo[b]pyran and pyrano[2,3-d]pyrimidinone derivatives were synthesized efficiently in the presence of KAl(SO4)2.12H2O (alum) in water. Green media, lack of toxicity, short reaction times, easy work-up and high yields are some advantages of this method.read more
Citations
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Journal ArticleDOI
Sulfonic acid-functionalized mesoporous silica (SBA-Pr-SO3H) as solid acid catalyst in organic reactions
TL;DR: In this article, a review of the catalytic activity of sulfonic acid-functionalized SBA-15 has been performed and it has been shown that the SBA can be easily removed from the reaction mixture by simple filtration, recovered and reused without significant loss of activity.
Journal ArticleDOI
Green approach towards the facile synthesis of dihydropyrano(c)chromene and pyrano[2,3-d]pyrimidine derivatives and their biological evaluation
TL;DR: A simple and efficient one-pot synthesis of heteroaryl-substituted dihydropyrano(c)chromenes and pyrano[2,3-d]pyrimidines has been developed as discussed by the authors.
Journal ArticleDOI
Nano α-Al2O3supported ammonium dihydrogen phosphate (NH4H2PO4/Al2O3): preparation, characterization and its application as a novel and heterogeneous catalyst for the one-pot synthesis of tetrahydrobenzo[b]pyran and pyrano[2,3-c]pyrazole derivatives
TL;DR: In this article, a simple, efficient, and environmentally benign route was developed for the preparation of 2-amino-3-cyano-4-aryl-7,7-dimethyl-5,6,7,8-tetrahydrobenzo[b]pyrans and 6amino,5-cyclohexanedione or 3-methyl-1-phenyl-2-pyrazoline-5-one with good yields.
Journal ArticleDOI
Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr-SO3H) and their docking and urease inhibitory activity
Ghodsi Mohammadi Ziarani,Sakineh Faramarzi,Shima Asadi,Alireza Badiei,Roya Bazl,Massoud Amanlou +5 more
TL;DR: The compounds with electron donating group and higher hydrophobic interaction with active site of enzyme prevents hydrolysis of substrate and reduced urease inhibitory activity are reported.
Journal ArticleDOI
Silica-coated magnetic NiFe2O4 nanoparticles-supported H3PW12O40; synthesis, preparation, and application as an efficient, magnetic, green catalyst for one-pot synthesis of tetrahydrobenzo[b]pyran and pyrano[2,3-c]pyrazole derivatives
Behrooz Maleki,Hossein Eshghi,Mohammad Barghamadi,Negar Nasiri,Amir Khojastehnezhad,Samaneh Sedigh Ashrafi,Omid Pourshiani +6 more
TL;DR: In this paper, a powerful, magnetic, supported, acid catalyst, NiFe2O4@SiO2−H3PW12O40, was prepared by chemical support of Keggin (H3pW12o40) heteropolyacid (HPA) on silica-coated NiFe 2O4 magnetic nanoparticles.
References
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Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
TL;DR: Reaction of R,â-Unsaturated Carbonyl Compounds 3127: Reaction of R-UnSaturated Carbonies 3127 7.1.6.
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Organic Synthesis “On Water”
Arani Chanda,Valery V. Fokin +1 more
TL;DR: The currently burgeoning field of organic synthesis in aqueous media encompasses a large family of reactions, and water is still not commonly used as a sole solvent for organic synthesis, at least in part because most organic compounds do not dissolve in water to a significant extent.
BookDOI
Organic synthesis in water
TL;DR: Aqueous transition metal catalyzed carbon-carbon bond pairing reactions in aqueous medium were studied in this paper, where base-catalyzed Aldol-and Michael-type condensations were used.
Journal ArticleDOI
Synthesis and pharmacological activity of 2-oxo-(2H) 1-benzopyran-3-carboxamide derivatives
TL;DR: In this article, the synthesis and biological activity of heterocyclic compounds synthesized by carbon suboxide was investigated and some 2-oxo (2H) 1-benzopyran-3-carboxamide derivatives were screened.
Journal ArticleDOI
Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine
TL;DR: In this paper, the synthesis of 2,4-diamino-7,8-dihydro-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine (BW301U, 7) by a route that has general applicability to the preparation of many 6-(substituted benzyl) 5-methyl pyridines is described.