Journal ArticleDOI
Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Ying Wan,Joe A. Vinson,Terry D. Etherton,John Proch,Sheryl A. Lazarus,Penny M. Kris-Etherton +5 more
TLDR
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility, increasing serum total antioxidant capacity and HDL-cholesterol concentrations, and not adversely affecting prostaglandins.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2001-11-01. It has received 342 citations till now. The article focuses on the topics: Dark chocolate & Oxygen radical absorbance capacity.read more
Citations
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Journal ArticleDOI
Plasma LDL and HDL Cholesterol and Oxidized LDL Concentrations Are Altered in Normo- and Hypercholesterolemic Humans after Intake of Different Levels of Cocoa Powder
Seigo Baba,Midori Natsume,Akiko Yasuda,Yuko Nakamura,Takaaki Tamura,Naomi Osakabe,Minoru Kanegae,Kazuo Kondo +7 more
TL;DR: It is suggested that polyphenolic substances derived from cocoa powder may contribute to a reduction in LDL cholesterol, an elevation in HDL cholesterol, and the suppression of oxidized LDL.
Journal ArticleDOI
Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players.
Cesar G. Fraga,Lucas Actis-Goretta,Javier I. Ottaviani,Fernando Carrasquedo,Silvina B. Lotito,Sheryl A. Lazarus,Harold H. Schmitz,Carl L. Keen +7 more
TL;DR: FCMC consumption was associated with changes in several variables often associated with cardiovascular health and oxidant stress, and the presence of significant quantities of flavanols in FCMC is likely to have been one of the contributing factors to these results.
Journal ArticleDOI
Cocoa products decrease low density lipoprotein oxidative susceptibility but do not affect biomarkers of inflammation in humans
TL;DR: It is concluded that cocoa products supplementation in humans affects LDL oxidizability, but not urinary F(2) isoprostanes or markers of inflammation, and there was no effect of chocolate on urinary F (2) wasoprostane levels or on markers ofinflammation.
Journal ArticleDOI
The Emerging Role of Flavonoid‐Rich Cocoa and Chocolate in Cardiovascular Health and Disease
TL;DR: Increasing evidence from experimental and clinical studies using cocoa-derived products and chocolate suggest an important role for these high-flavanol-containing foods in heart and vascular protection.
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Flavanol-rich cocoa drink lowers plasma F(2)-isoprostane concentrations in humans.
Ingrid Wiswedel,Daniela Hirsch,Siegfried Kropf,Martin Gruening,Eberhard Alexander Pfister,Tankred Schewe,Helmut Sies +6 more
TL;DR: It is concluded that dietary flavanols, using cocoa drink as example, can lower the plasma level of F(2)-isoprostanes, indicators of in vivo lipid peroxidation.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
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Beyond cholesterol, modifications of low-density lipoprotein that increase its atherogenicity
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Continuous monitoring of in vitro oxidation of human low density lipoprotein.
TL;DR: The kinetics of the oxidation of human low densit) lipoprotein (LDL) can be measured continuously by monitoring the change of the 234 nm diene absorption as discussed by the authors.
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Polyphenolic Flavanols as Scavengers of Aqueous Phase Radicals and as Chain-Breaking Antioxidants
N. Salah,Nicholas J. Miller,George Paganga,Lilian B. M. Tijburg,G.P. Bolwell,Catherine Rice-Evans +5 more
TL;DR: Against propagating lipid peroxyl radical species, epicatechin and catechin are as effective as ECG and EGCG, the least efficacious being EGC and GA.