Journal ArticleDOI
Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Ying Wan,Joe A. Vinson,Terry D. Etherton,John Proch,Sheryl A. Lazarus,Penny M. Kris-Etherton +5 more
TLDR
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility, increasing serum total antioxidant capacity and HDL-cholesterol concentrations, and not adversely affecting prostaglandins.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2001-11-01. It has received 342 citations till now. The article focuses on the topics: Dark chocolate & Oxygen radical absorbance capacity.read more
Citations
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Journal ArticleDOI
Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer
Penny M. Kris-Etherton,Kari D Hecker,Andrea Bonanome,Stacie M. Coval,Amy E. Binkoski,Kirsten F Hilpert,Amy E. Griel,Terry D. Etherton +7 more
TL;DR: Many bioactive compounds are extranutritional constituents that typically occur in small quantities in foods and are grouped accordingly as phenolic compounds, including their subcategory, flavonoids as discussed by the authors.
Journal ArticleDOI
Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Gary Williamson,Claudine Manach +1 more
TL;DR: It is time to rethink the design of in vitro and in vivo studies, so that these issues are carefully considered, and the length of human intervention studies should be increased, to more closely reflect the long-term dietary consumption of polyphenols.
Journal ArticleDOI
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Silvina B. Lotito,Balz Frei +1 more
TL;DR: It is concluded that the large increase in plasma total antioxidant capacity observed after the consumption of flavonoid-rich foods is not caused by the flavonoids themselves, but is likely the consequence of increased uric acid levels.
Journal ArticleDOI
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?
TL;DR: It is argued that tocopherols and tocotrienols may also exert direct beneficial effects in the gastrointestinal tract and that their return to theintestinal tract by the liver through the bile may be physiologically advantageous.
Journal ArticleDOI
Polyphenols and prevention of cardiovascular diseases.
TL;DR: Future intervention studies should include a detailed assessment of the bioavailability of polyphenols, and more studies with purepolyphenols will also be needed to establish their role in the prevention of cardiovascular diseases.
References
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Journal ArticleDOI
Chocolate as a source of tea flavonoids.
TL;DR: Chocolate contributed 20% of the catechin intake in a representative sample of the Dutch population, and tea contributes 55%.
Book ChapterDOI
Role of flavonoids and iron chelation in antioxidant action.
TL;DR: This chapter discusses the role of flavonoids and iron chelation in antioxidant action, and uses rat as a biological model where lipid peroxidation is induced by iron in its complexed form with nitrilotriacetic acid.
Journal ArticleDOI
Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation
TL;DR: Low-density lipoprotein oxidation was measured in vitro to determine intraindividual variability and to relate oxidation to linoleic acid enrichment and was not significantly altered by the linoleate-rich diet.
Journal ArticleDOI
The role of fatty acid saturation on plasma lipids, lipoproteins, and apolipoproteins: I. Effects of whole food diets high in cocoa butter, olive oil, soybean oil, dairy butter, and milk chocolate on the plasma lipids of young men☆
Penny M. Kris-Etherton,Penny M. Kris-Etherton,Janice Derr,Janice Derr,Diane C. Mitchell,Diane C. Mitchell,Vikkie A. Mustad,Vikkie A. Mustad,Mary E. Russell,Mary E. Russell,Elaine McDonnell,Elaine McDonnell,Deborah Salabsky,Deborah Salabsky,Thomas A. Pearson,Thomas A. Pearson +15 more
TL;DR: Evaluating the cholesterolemic effects of whole-food diets high in stearic acid found low-density lipoprotein (LDL) cholesterol levels paralleled the changes in plasma total cholesterol levels, in general.
Journal ArticleDOI
Antioxidant capacity and polyphenolic components of teas: implications for altering in vivo antioxidant status.
TL;DR: In this article, the Oxygen Radical Absorbance Capacity (ORAC) assay was used to determine the total antioxidant capacity of tea, and the results showed that green and black tea had a mean ORAC of 761.1 +/- 85.3 micromol Trolox equivalents (TE) per g dry matter.