Journal ArticleDOI
Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Ying Wan,Joe A. Vinson,Terry D. Etherton,John Proch,Sheryl A. Lazarus,Penny M. Kris-Etherton +5 more
TLDR
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility, increasing serum total antioxidant capacity and HDL-cholesterol concentrations, and not adversely affecting prostaglandins.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2001-11-01. It has received 342 citations till now. The article focuses on the topics: Dark chocolate & Oxygen radical absorbance capacity.read more
Citations
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Journal ArticleDOI
Chocolate and Cardiovascular Health: Is It Too Good To Be True?
TL;DR: Several unresolved issues are raised that suggest the need for additional research and product development in this area of flavonoids, particularly catechin and epicatechin.
Journal ArticleDOI
Protective Role of Catechin on d-Galactosamine Induced Hepatotoxicity Through a p53 Dependent Pathway
P. Vasanth Raj,K. Nitesh,Sagar Shanti Mal Gang,V. Hitesh Jagani,H Raghu Chandrashekhar,J. Venkata Rao,C. Mallikarjuna Rao,Nayanabhirama Udupa +7 more
TL;DR: It was found that increases in the liver enzyme activity and decrease in antioxidant enzyme activity by d-GalN were significantly restricted by oral pretreatment with catechin, and disruption of mitochondrial membrane potential, up regulation of p53, Bax and down regulation of Bcl-2 mRNA levels in the hepatotoxicity of d-galactosamine intoxicated rats were effectively prevented by Pretreatment with Catechin.
Journal ArticleDOI
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar-Unilever rats.
Jean-François Bisson,Maria-Alba Guardia-Llorens,Sophie Hidalgo,Pascale Rozan,Michaël Messaoudi +4 more
TL;DR: Acticoa powder at 24 mg/kg protected rats from prostate carcinogenesis when chronically given before the initiation and promotion phases of induction.
Journal ArticleDOI
Caracterización de la fibra de cacao y su efecto sobre la capacidad antioxidante en suero de animales de experimentación
Elena Lecumberri,Raquel Mateos,Sonia Ramos,Margarita Alía,Pilar Rupérez,Luis Goya,M. Izquierdo-Pulido,Laura Bravo +7 more
TL;DR: In this article, the effect of the administration of a polyphenolic extract of this cocoa fiber on the antioxidant capacity of the serum in rats was investigated, which was determined by means of its reduction power and the capacity to scavenge free radicals.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
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Beyond cholesterol, modifications of low-density lipoprotein that increase its atherogenicity
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Continuous monitoring of in vitro oxidation of human low density lipoprotein.
TL;DR: The kinetics of the oxidation of human low densit) lipoprotein (LDL) can be measured continuously by monitoring the change of the 234 nm diene absorption as discussed by the authors.
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Polyphenolic Flavanols as Scavengers of Aqueous Phase Radicals and as Chain-Breaking Antioxidants
N. Salah,Nicholas J. Miller,George Paganga,Lilian B. M. Tijburg,G.P. Bolwell,Catherine Rice-Evans +5 more
TL;DR: Against propagating lipid peroxyl radical species, epicatechin and catechin are as effective as ECG and EGCG, the least efficacious being EGC and GA.