Journal ArticleDOI
Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Ying Wan,Joe A. Vinson,Terry D. Etherton,John Proch,Sheryl A. Lazarus,Penny M. Kris-Etherton +5 more
TLDR
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility, increasing serum total antioxidant capacity and HDL-cholesterol concentrations, and not adversely affecting prostaglandins.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2001-11-01. It has received 342 citations till now. The article focuses on the topics: Dark chocolate & Oxygen radical absorbance capacity.read more
Citations
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Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action
David Vauzour,Ana Rodriguez-Mateos,Giulia Corona,Maria Jose Oruna-Concha,Jeremy P. E. Spencer +4 more
TL;DR: The role that polyphenols play in the prevention of cancer, cardiovascular disease and neurodegeneration is provided and epidemiological data, human intervention study findings, as well as animal and in vitro studies in support of these actions are presented.
Journal ArticleDOI
Functional Foods: Benefits, Concerns and Challenges—A Position Paper from the American Council on Science and Health
TL;DR: This review categorizes a variety of functional foods according to the type of evidence supporting their functionality, the strength of that evidence and the recommended intakes.
Journal ArticleDOI
Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials
Lee Hooper,Colin D. Kay,Asmaa Abdelhamid,Paul A. Kroon,Jeffrey S Cohn,Eric B. Rimm,Aedin Cassidy +6 more
TL;DR: Chocolate or cocoa improved FMD regardless of the dose consumed, whereas doses >50 mg epicatechin/d resulted in greater effects on systolic and diastolic BP, and previously unreported promising effects on insulin and HOMA-IR were found.
Journal ArticleDOI
Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adults.
Mary B. Engler,Marguerite M. Engler,Chung Y. Chen,Mary J. Malloy,Amanda E.M. Browne,Elisa Y. Chiu,Ho-Kyung Kwak,Paul E. Milbury,Steven M. Paul,Jeffrey B. Blumberg,Michele Mietus-Snyder +10 more
TL;DR: Flavonoid-rich dark chocolate improves endothelium-dependent flow-mediated dilation of the brachial artery and is associated with an increase in plasma epicatechin concentrations in healthy adults.
Journal ArticleDOI
Cocoa intake, blood pressure, and cardiovascular mortality: the Zutphen Elderly Study.
TL;DR: In a cohort of elderly men, cocoa intake is inversely associated with blood pressure and 15-year cardiovascular and all-cause mortality.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
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Beyond cholesterol, modifications of low-density lipoprotein that increase its atherogenicity
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Continuous monitoring of in vitro oxidation of human low density lipoprotein.
TL;DR: The kinetics of the oxidation of human low densit) lipoprotein (LDL) can be measured continuously by monitoring the change of the 234 nm diene absorption as discussed by the authors.
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Polyphenolic Flavanols as Scavengers of Aqueous Phase Radicals and as Chain-Breaking Antioxidants
N. Salah,Nicholas J. Miller,George Paganga,Lilian B. M. Tijburg,G.P. Bolwell,Catherine Rice-Evans +5 more
TL;DR: Against propagating lipid peroxyl radical species, epicatechin and catechin are as effective as ECG and EGCG, the least efficacious being EGC and GA.