Journal ArticleDOI
Effects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humans
Ying Wan,Joe A. Vinson,Terry D. Etherton,John Proch,Sheryl A. Lazarus,Penny M. Kris-Etherton +5 more
TLDR
Cocoa powder and dark chocolate may favorably affect cardiovascular disease risk status by modestly reducing LDL oxidation susceptibility, increasing serum total antioxidant capacity and HDL-cholesterol concentrations, and not adversely affecting prostaglandins.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2001-11-01. It has received 342 citations till now. The article focuses on the topics: Dark chocolate & Oxygen radical absorbance capacity.read more
Citations
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Cocoa Polyphenols and Inflammatory Markers of Cardiovascular Disease
Nasiruddin Khan,Olha Khymenets,Mireia Urpi-Sarda,Sara Tulipani,Mar Garcia-Aloy,María Monagas,Ximena Mora-Cubillos,Rafael Llorach,Cristina Andres-Lacueva +8 more
TL;DR: Accumulated evidence on related anti-inflammatory effects of cocoa polyphenols is summarized in the present review.
Journal ArticleDOI
The anti-inflammatory properties of cocoa flavanols.
TL;DR: Flavanol-rich cocoa could be a potential candidate for the treatment, or possibly prevention, of the broad array of chronic diseases that are linked to dysfunctional inflammatory responses, and additional research in well-designed human clinical experiments would be a welcome addition to the evidence base.
Journal ArticleDOI
Bioactive polyphenols and cardiovascular disease: chemical antagonists, pharmacological agents or xenobiotics that drive an adaptive response?
Katarzyna Goszcz,Garry G. Duthie,Derek Stewart,Derek Stewart,Stephen J. Leslie,Stephen J. Leslie,Ian L. Megson +6 more
TL;DR: The implications are that in vitro antioxidant measures as predictors of polyphenol protective activity in vivo hold little relevance and that closer attention needs to be paid to bioavailable metabolites to understand the mode of action of these diet‐derived components.
Journal ArticleDOI
Proanthocyanidins: Biological Activities Associated with Human Health
TL;DR: Results from a variety of experiments indicate proanthocyanidins may modulate several reactions involved in cancer processes, and a crucial research need is to identify further biologically active components of proanthic flavans so that mechanisms of action at the tissue, cellular, and subcellular levels can be elucidated.
Journal ArticleDOI
Hepatoprotective Effect of Green Tea (Camellia sinensis) Extract against Tamoxifen-induced Liver Injury in Rats
TL;DR: The data obtained from this study speculated that 1.5 % GTE has the capacity to scavenge free radical and can protect against oxidative stress induced by TAM intoxication and could be useful in alleviating tamoxifen-induced liver injury in rats.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
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Beyond cholesterol, modifications of low-density lipoprotein that increase its atherogenicity
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Continuous monitoring of in vitro oxidation of human low density lipoprotein.
TL;DR: The kinetics of the oxidation of human low densit) lipoprotein (LDL) can be measured continuously by monitoring the change of the 234 nm diene absorption as discussed by the authors.
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Polyphenolic Flavanols as Scavengers of Aqueous Phase Radicals and as Chain-Breaking Antioxidants
N. Salah,Nicholas J. Miller,George Paganga,Lilian B. M. Tijburg,G.P. Bolwell,Catherine Rice-Evans +5 more
TL;DR: Against propagating lipid peroxyl radical species, epicatechin and catechin are as effective as ECG and EGCG, the least efficacious being EGC and GA.