Efficacy and Durability of Radiofrequency Ablation for Barrett’s Esophagus: Systematic Review and Meta-analysis
TLDR
Treatment of BE with RFA results in CE-D and CE-IM in a high proportion of patients, with few recurrences of IM after treatment and a low rate of adverse events.About:
This article is published in Clinical Gastroenterology and Hepatology.The article was published on 2013-10-01 and is currently open access. It has received 256 citations till now. The article focuses on the topics: Retrospective cohort study & Barrett's esophagus.read more
Citations
More filters
Journal ArticleDOI
Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial
K. Nadine Phoa,Frederike G. Van Vilsteren,Bas L. Weusten,Raf Bisschops,Erik J. Schoon,Krish Ragunath,Grant Fullarton,Massimiliano di Pietro,Narayanasamy Ravi,Mike Visser,G. Johan A. Offerhaus,Cees A. Seldenrijk,Sybren L. Meijer,Fiebo J.W. ten Kate,Jan G.P. Tijssen,Jacques J. Bergman +15 more
TL;DR: Radiofrequency ablation resulted in a reduced risk of neoplastic progression over 3 years of follow-up and the data and safety monitoring board recommended early termination of the trial due to superiority of ablation for the primary outcome and the potential for patient safety issues if the trial continued.
Journal ArticleDOI
Epidemiology, Diagnosis, and Management of Esophageal Adenocarcinoma.
TL;DR: The prognosis is based on tumor stage; patients with T1a tumors have an excellent prognosis, whereas few patients with advanced disease have long-term survival.
Journal ArticleDOI
Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma
Caryn S. Ross-Innes,Jennifer Becq,Andrew Warren,R. Keira Cheetham,Helen Northen,Maria O'Donovan,Shalini Malhotra,Massimiliano di Pietro,Sergii Ivakhno,Miao He,Jamie M J Weaver,Andy G. Lynch,Zoya Kingsbury,Mark T. Ross,Sean Humphray,David Bentley,Rebecca C. Fitzgerald +16 more
TL;DR: From a clinical perspective, the histopathological assessment of dysplasia appears to be a poor reflection of the molecular disarray within the Barrett's epithelium, and a molecular Cytosponge technique overcomes sampling bias and has the capacity to reflect the entire clonal architecture.
Journal ArticleDOI
Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Screening, Diagnosis, and Therapy
TL;DR: The state-of-the-art technologies for early diagnosis and minimally invasive treatment of esophageal cancer using resection and ablation technologies supported by evidence from randomized controlled trials are reviewed.
Journal ArticleDOI
Adverse Events After Radiofrequency Ablation in Patients With Barrett's Esophagus: A Systematic Review and Meta-analysis.
Bashar J. Qumseya,Sachin Wani,Madhav Desai,Amira Qumseya,Paul A. Bain,Prateek Sharma,Herbert C. Wolfsen +6 more
TL;DR: The relative risk for adverse events from RFA is found to be about 4-fold higher with EMR than without; factors associated with these events should be discussed with patients before endoscopic eradication therapy.
References
More filters
Journal ArticleDOI
Meta-Analysis in Clinical Trials*
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
Journal ArticleDOI
Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
Journal ArticleDOI
Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI
The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions.
Sara H. Downs,Nick Black +1 more
TL;DR: It is shown that it is feasible to develop a checklist that can be used to assess the methodological quality not only of randomised controlled trials but also non-randomised studies and it is possible to produce a Checklist that provides a profile of the paper, alerting reviewers to its particular methodological strengths and weaknesses.
Journal ArticleDOI
Transformations Related to the Angular and the Square Root
Murray F. Freeman,John W. Tukey +1 more
TL;DR: In this paper, an empirical study of a number of approximations for variance stabilization is presented, some intended for significance and confidence work and others for variance stabilisation for Poisson data.
Related Papers (5)
Radiofrequency Ablation in Barrett's Esophagus with Dysplasia
Nicholas J. Shaheen,Prateek Sharma,Bergein F. Overholt,Herbert C. Wolfsen,Richard E. Sampliner,Kenneth K. Wang,Joseph A. Galanko,Mary P. Bronner,John R. Goldblum,Ana E. Bennett,Blair A. Jobe,Glenn M. Eisen,M. Brian Fennerty,John G. Hunter,David E. Fleischer,Virender K. Sharma,Robert H. Hawes,Brenda J. Hoffman,Richard I. Rothstein,Stuart R. Gordon,Hiroshi Mashimo,Kenneth J. Chang,V. Raman Muthusamy,Steven A. Edmundowicz,Stuart J. Spechler,Ali A. Siddiqui,Rhonda F. Souza,Anthony Infantolino,Gary W. Falk,Michael B. Kimmey,Ryan D. Madanick,Amitabh Chak,Charles J. Lightdale +32 more