Journal ArticleDOI
Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds—a critical review
TLDR
A literature review on QAC chemical structure, fields of application, mechanism of action, susceptibility testing, prevalence, and co- or cross-resistance to antibiotics found that there is a lack of standardised procedures for interpreting susceptibility test results.About:
This article is published in International Journal of Antimicrobial Agents.The article was published on 2012-05-01. It has received 461 citations till now.read more
Citations
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Journal ArticleDOI
Antibacterial surfaces: the quest for a new generation of biomaterials.
TL;DR: Several recent efforts to design a new generation of antibacterial surfaces, which are based on mimicking the surface nanotopography of natural surfaces, are considered.
Journal ArticleDOI
Graphene quantum dots-band-aids used for wound disinfection.
TL;DR: To assess the antibacterial efficacy of the designed system in actual wound disinfection, the GQD-Band-Aids are prepared and show excellent antibacterial property with the assistance of H2O2 at low dose in vivo.
Journal ArticleDOI
Review of Antimicrobial Resistance in the Environment and Its Relevance to Environmental Regulators
TL;DR: It is argued that the lack of environment-facing mitigation actions included in existing AMR action plans is likely a function of the authors' poor fundamental understanding of many of the key issues and the science to inform policy is lacking and this needs to be addressed.
Journal ArticleDOI
Microbes in the neonatal intensive care unit resemble those found in the gut of premature infants
Brandon Brooks,Brian Firek,Christopher S. Miller,Christopher S. Miller,Itai Sharon,Brian C. Thomas,Robyn Baker,Michael J. Morowitz,Jillian F. Banfield +8 more
TL;DR: This first matched fecal-BE time series analysis of two preterm VLBW neonates housed in a neonatal intensive care unit (NICU) over the first month of life reveals a suite of genes that confer resistance to antibiotics and sterilizing agents, which likely offer a competitive advantage in the NICU environment.
Journal ArticleDOI
Bifunctionalized mesoporous silica-supported gold nanoparticles: intrinsic oxidase and peroxidase catalytic activities for antibacterial applications.
TL;DR: Taking advantage of their prominent enzyme activities, the MSN-AuNPs show excellent antibacterial properties against both Gram-negative and Gram-positive bacteria.
References
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Journal ArticleDOI
Characterization of a New Metallo-β-Lactamase Gene, blaNDM-1, and a Novel Erythromycin Esterase Gene Carried on a Unique Genetic Structure in Klebsiella pneumoniae Sequence Type 14 from India
Dongeun Yong,Mark Toleman,Christian G. Giske,Hyun Sun Cho,Kristina Sundman,Kyungwon Lee,Timothy R. Walsh +6 more
TL;DR: A Swedish patient of Indian origin traveled to New Delhi, India, and acquired a urinary tract infection caused by a carbapenem-resistant Klebsiella pneumoniae strain that typed to the sequence type 14 complex, showing broad resistance carried on these plasmids.
Book
Disinfection, sterilization, and preservation
TL;DR: Infection, sterilization, and preservation, Disinfection, Sterility, and Preservation, کتابخانه دیجیتال جندی اهواز.
Journal ArticleDOI
Multidrug-resistance efflux pumps ? not just for resistance
TL;DR: Evidence is presented that multidrug-resistance efflux pumps have roles in bacterial pathogenicity and it is proposed that these pumps therefore have greater clinical relevance than is usually attributed to them.
Journal ArticleDOI
Cationic antiseptics: diversity of action under a common epithet.
Peter Gilbert,Louise E. Moore +1 more
TL;DR: Action mechanisms for cationic antimicrobials are examined and key differences that render them distinct categories of antibacterial agent are highlighted that have profound implications in terms of cross-resistance.
Book
Pharmaceuticals in the environment : sources, fate, effects and risks
TL;DR: This work discusses the potential benefits of Small Animal Models for the Aquatic Hazard Assessment of Human Pharmaceuticals, and strategies for Reducing the Input of Pharmaceuticals into the Environment.
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Cationic antiseptics: diversity of action under a common epithet.
Peter Gilbert,Louise E. Moore +1 more