Journal ArticleDOI
Epidemiology and Clinical Features of Sporadic Hepatitis E as Compared with Hepatitis A
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TLDR
Hepatitis E is a more severe disease entity as compared with hepatitis A and significant proportion of them are imported cases from an endemic area.About:
This article is published in The American Journal of Gastroenterology.The article was published on 2006-02-01. It has received 80 citations till now. The article focuses on the topics: Hepatitis E virus & Viral hepatitis.read more
Citations
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Journal ArticleDOI
Acute Hepatitis E Infection Accounts for Some Cases of Suspected Drug-Induced Liver Injury
Timothy Davern,Naga Chalasani,Robert J. Fontana,Paul H. Hayashi,Petr Protiva,David E. Kleiner,Ronald E. Engle,Hanh Nguyen,Suzanne U. Emerson,Robert H. Purcell,Hans L. Tillmann,Jiezhun Gu,Jose Serrano,Jay H. Hoofnagle +13 more
TL;DR: HEV infection contributes to a small but important proportion of cases of acute liver injury that are suspected to be drug induced, andSerologic testing for HEV infection should be performed, particularly if clinical features are compatible with acute viral hepatitis.
Journal ArticleDOI
Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention.
TL;DR: Hepatitis E virus (HEV) is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries as mentioned in this paper.
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Fulminant liver failure from acute autochthonous hepatitis E in France: description of seven patients with acute hepatitis E and encephalopathy.
Jean-Marie Péron,Christophe Bureau,Hélène Poirson,Jean-Michel Mansuy,Laurent Alric,J. Selves,E. Dupuis,Jacques Izopet,Jean-Pierre Vinel +8 more
TL;DR: When compared with patients with a mild form of acute hepatitis E, active alcohol abuse and chronic liver disease were more frequent in patients with the severe form and death was more frequent.
Journal ArticleDOI
Fulminant Hepatitis A Virus Infection in the United States: Incidence, Prognosis, and Outcomes
Ryan M. Taylor,Timothy J. Davern,Santiago J. Munoz,Stephen Huy Han,Brendan M. McGuire,Anne M. Larson,Linda S. Hynan,William M. Lee,Robert J. Fontana +8 more
TL;DR: A prognostic index consisting of 4 clinical and laboratory features predicted the likelihood of transplant/death significantly better than other published models suggesting that disease specific prognostic models may be of value in non‐acetaminophen ALF.
Journal ArticleDOI
Randomized-controlled phase II clinical trial of a bacterially expressed recombinant hepatitis E vaccine.
Jun Zhang,Chong-bo Liu,Rong-Cheng Li,Yimin Li,Yingjie Zheng,Yan-ping Li,Dong Luo,Bai-bin Pan,Yi Nong,Shengxiang Ge,Junhui Xiong,James Wai-Kuo Shih,Mun-Hon Ng,Ningshao Xia +13 more
TL;DR: The results showed that the candidate recombinant hepatitis E vaccine is safe and immunogenic for humans and suggest that it could prevent new HEV infection.
References
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Journal ArticleDOI
Zoonotic transmission of hepatitis E virus from deer to human beings
TL;DR: Findings provide direct evidence for HEV infection to be a zoonosis among people who had eaten uncooked deer meat 6-7 weeks before and patients' family members who ate none or very little of the deer meat remained uninfected.
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Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food
Yasuyuki Yazaki,Hitoshi Mizuo,Masaharu Takahashi,Tsutomu Nishizawa,Nobuhiko Sasaki,Yuhko Gotanda,Hiroaki Okamoto +6 more
TL;DR: Results indicate that inadequately cooked pig liver may transmit HEV to humans.
Short Communication Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food
Yasuyuki Yazaki,Hitoshi Mizuo,Masaharu Takahashi,Tsutomu Nishizawa,Nobuhiko Sasaki,Yuhko Gotanda,Hiroaki Okamoto +6 more
TL;DR: In this article, the presence of hepatitis E virus (HEV) RNA by RT-PCR was found in packages of raw pig liver sold in grocery stores as food in Hokkaido.
Journal ArticleDOI
Prevalence of Antibodies to Hepatitis E Virus in Veterinarians Working with Swine and in Normal Blood Donors in the United States and Other Countries
Xiang-Jin Meng,Barry Wiseman,François Elvinger,D. K. Guenette,Thomas E. Toth,Ronald E. Engle,Suzanne U. Emerson,Robert H. Purcell +7 more
TL;DR: There was a difference in anti- HEV prevalence in both swine veterinarians and blood donors among the eight selected states, with subjects from Minnesota six times more likely to be anti-HEV positive than those from Alabama, and age was not a factor in the observed differences.
Journal ArticleDOI
Epidemic and endemic hepatitis in india: evidence for a non-a, non-b hepatitis virus ætiology
DorisC. Wong,DorisC. Wong,Robert H. Purcell,Robert H. Purcell,Mandyam Ammanjee Sreenivasan,Mandyam Ammanjee Sreenivasan,Subba Rama Prasad,Subba Rama Prasad,KhorshedM. Pavri,KhorshedM. Pavri +9 more
TL;DR: 69 serum pairs from two common-source water-borne outbreaks and one series of endemic cases of hepatitis in three parts of India were tested for hepatitis A and hepatitis B virus infections and none of the patients had evidence of HAV infection.